A Rising Cluster of Erythropoietin-Associated Pure Red Cell Aplasia and Subsequent Response to Roxadustat: A Case Series [0.03%]
一例促红细胞生成素相关纯红细胞再生障碍性贫血的发病及后续对罗沙司他治疗有良好反应:系列病例报告
Jayana Devathasan,Tze Liang Goh,Daniel Chou-Yen Lin et al.
Jayana Devathasan et al.
Patients with chronic kidney disease (CKD) develop anaemia in the setting of abnormal iron metabolism and reduced endogenous erythropoietin. Pure red cell aplasia (PRCA) is a condition that, in rare cases, has been associated with erythropo...
Case Reports
Nephrology (Carlton, Vic.). 2026 Feb;31(2):e70169. DOI:10.1111/nep.70169 2026
Targeting TBK1 With GSK8612 Suppresses Kidney and Cardiac Inflammation and Fibrosis in DOCA/Salt Hypertension [0.03%]
新型小分子TBK1抑制剂GSK8612可减轻DOCA盐高血压大鼠肾脏和心脏炎症及纤维化损伤
Jiamin Huang,Wei Rong,Ling Li et al.
Jiamin Huang et al.
Aim: To investigate the therapeutic potential of GSK8612, a selective TBK1 inhibitor, against the inflammatory and fibrotic pathological remodeling in the heart and kidneys induced by DOCA/salt hypertension in mice. ...
GSTO1 as a Potential Risk Factor for Diabetic Nephropathy: Evidence From Mendelian Randomisation and Multi-Omics Analyses [0.03%]
GSTO1可能是糖尿病肾病的风险因素:来自孟德尔随机化和多组学分析的证据
Jiang Tan,Sisi Lei,Liang Zhao et al.
Jiang Tan et al.
Aim: Diabetic nephropathy (DN) is a major complication of diabetes mellitus and a leading cause of end-stage renal disease (ESRD). Glutathione S-transferase omega 1 (GSTO1) is implicated in redox regulation and inflammati...
Efficacy of Desmopressin for Post-Kidney Biopsy Bleeding Complications Prevention: A Systematic Review With Frequentist and Bayesian Meta-Analysis [0.03%]
抗利尿激素预防肾穿刺术后出血的系统评价和meta分析
Jia-Jin Chen,Tao-Han Lee,Pei-Chun Lai et al.
Jia-Jin Chen et al.
Aim: Desmopressin was hypothesised to prevent post-kidney biopsy bleeding; however, its efficacy in reducing bleeding and bleeding-related complications has yet to be systematically examined. ...
Meta-Analysis
Nephrology (Carlton, Vic.). 2026 Jan;31(1):e70164. DOI:10.1111/nep.70164 2026
Renal Hypouricemia Type 2 due to a Novel Homozygous SLC2A9 Variant: Exercise-Induced Acute Kidney Injury in One of Two Affected Siblings [0.03%]
新型SLC2A9同质变异引起的肾低尿酸血症2型:一名患病兄弟的运动诱发急性肾损伤
Ignacia Pezantes,Paola Krall,Blanka Stiburkova et al.
Ignacia Pezantes et al.
We present the case of an adult male with repeated episodes of post-exercise acute renal injury. His biochemical study revealed severe hypouricemia with very high fractional excretion of urate and a genetic study showed the presence of an u...
Case Reports
Nephrology (Carlton, Vic.). 2026 Jan;31(1):e70163. DOI:10.1111/nep.70163 2026
A Comprehensive Analysis of Serum and Urine Bile Acid Profiles in Chronic Kidney Disease: An Exploratory Study of Clinical Associations [0.03%]
慢性肾脏病血清和尿液胆汁酸谱的全面分析:临床相关性的探索性研究
Takeo Koshida,Hiroshi Nittono,Hajime Takei et al.
Takeo Koshida et al.
Aim: Dysbiosis contributes to systemic inflammation and the accumulation of uremic toxins, leading to end-stage kidney disease. However, the role of bile acids (BAs), key metabolic products of the gut microbiota, in the p...
Global, Regional, and National Burden of Acute Glomerulonephritis From 1990 to 2021: A Systematic Analysis for the Global Burden of Disease Study 2021 [0.03%]
1990年至2021年全球、区域和国家急性肾小球肾炎疾病负担的系统分析:全球疾病负担研究2021年的结果
Shan Hou,Liang Zhang,Xindi Wang et al.
Shan Hou et al.
Background: This study examined recent trends in the prevalence, incidence, mortality and disability-adjusted life years (DALYs) associated with acute glomerulonephritis, a global health challenge, using data from the Glo...
Khalid A Alhasan,Walaa Alshammasi,Suha Salim et al.
Khalid A Alhasan et al.
Aim: This study aimed to determine age-related reference values, focusing on infant urinary solute-to-urinary creatinine concentration ratios (urinary calcium, urinary phosphate, urinary sodium, urinary magnesium, urinary...
Marcos Adriano Garcia Campos,Precil Diego Miranda de Meneses Neves,Érico Murilo Monteiro Cutrim et al.
Marcos Adriano Garcia Campos et al.
Aim: Collapsing glomerulopathy (CG) is a glomerular disease that progresses rapidly to renal replacement therapy (RRT). Brazil is a conducive site for studies on CG because of its significant burden of infectious diseases...
Multicenter Study
Nephrology (Carlton, Vic.). 2025 Dec;30(12):e70158. DOI:10.1111/nep.70158 2025
Dual Anti-Neutrophil Cytoplasmic Antibody and Anti-Glomerular Basement Membrane Antibody-Positive Crescentic Glomerulonephritis in a Patient With Monoclonal Gammopathy and Elevated IgG4 Levels: A Case Report and Literature Review [0.03%]
单克隆丙种球蛋白病伴IgG4升高患者的双抗体阳性的新月体性肾炎一例报告及文献复习
Yu Gu,Zhong Zhong,Na-Ya Huang et al.
Yu Gu et al.
The aetiology of crescentic glomerulonephritis is multifactorial, with anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and anti-glomerular basement membrane (GBM) antibody disease being well-documented causes. Monocl...