Mitochondrial DNA replication is essential for neurogenesis but not gliogenesis in fetal neural stem cells [0.03%]
线粒体DNA复制在胎儿神经干细胞中是神经发生所必需的，而不是星形细胞发生所必需的
Meri Walter-Manucharyan,Melanie Martin,Julia Pfützner et al.
Meri Walter-Manucharyan et al.
Mitochondria are unique organelles that have their own genome (mtDNA) and perform various pivotal functions within a cell. Recently, evidence has highlighted the role of mitochondria in the process of stem cell differentiation, including di...
Lineage tracing of Shh+ floor plate cells and dynamics of dorsal-ventral gene expression in the regenerating axolotl spinal cord [0.03%]
轴棘螈脊髓再生过程中Shh+底板细胞的谱系追踪及背腹基因表达动态变化研究
Laura I Arbanas,Emanuel Cura Costa,Osvaldo Chara et al.
Laura I Arbanas et al.
Both development and regeneration depend on signaling centers, which are sources of locally secreted tissue-patterning molecules. As many signaling centers are decommissioned before the end of embryogenesis, a fundamental question is how si...
Establishment and characterization of mouse lines useful for endogenous protein degradation via an improved auxin-inducible degron system (AID2) [0.03%]
改良型 Auxin 诱导性降解系统(AID2)小鼠品系的建立及其特性分析
Hatsune Makino-Itou,Noriko Yamatani,Akemi Okubo et al.
Hatsune Makino-Itou et al.
The development of new technologies opens new avenues in the research field. Gene knockout is a key method for analyzing gene function in mice. Currently, conditional gene knockout strategies are employed to examine temporal and spatial gen...
Chicken embryo cultures in the dorsal-upward orientation for the manipulation of epiblasts [0.03%]
背向上位姿势鸡胚胎培养体系的建立及对上胚层细胞的操作研究
Kaho Konya,Yusaku Watanabe,Akihito Kawamura et al.
Kaho Konya et al.
Chicken embryos have many advantages in the study of amniote embryonic development. In particular, culture techniques developed for early-stage embryos have promoted the advancement of modern developmental studies using chicken embryos. How...
Meeting report of the 57th Annual Meeting of the Japanese Society for Developmental Biologists [0.03%]
日本发育生物学会第57届年会会议报告
Yuzuka Takeuchi
Yuzuka Takeuchi
The 57th Annual Meeting of the Japanese Society for Developmental Biologists was held at Miyako Messe and ROHM Theater Kyoto from June 19 to 22, 2024. After the COVID-19 pandemic, this was the first meeting where all restrictions were remov...
Atsushi Shibai,Chikara Furusawa
Atsushi Shibai
Experimental evolution of microbial cells provides valuable information on evolutionary dynamics, such as mutations that contribute to fitness gain under given selection pressures. Although experimental evolution is a promising tool in evol...
The self-in-the-world map emerged in the primate brain as a basis for Homo sapiens abilities [0.03%]
自我不凡的起源：灵长类动物大脑中的“自我在世地图”是智人的基础能力出现的前提
Rafael Bretas,Banty Tia,Atsushi Iriki
Rafael Bretas
The brain in the genus Homo expanded rapidly during evolution, accelerated by a reciprocated interaction between neural, cognitive, and ecological niches (triadic niche construction, or TNC). This biologically costly expansion incubated lat...
Li-Kun Phng,Benjamin M Hogan
Li-Kun Phng
In recent decades, developmental biologists have come to view vascular development as a series of progressive transitions. Mesoderm differentiates into endothelial cells; arteries, veins and lymphatic endothelial cells are specified from ea...
Kenta Watai,Kenichiro Sadamitsu,Seiji Wada et al.
Kenta Watai et al.
Parkinson's disease is a neurological disorder characterized by reduced motility, depression and dementia. Guamanian parkinsonism dementia with amyotrophic sclerosis is a local case of Parkinson's disease reported in the Western Pacific Isl...
Differential cellular stiffness across tissues that contribute to Xenopus neural tube closure [0.03%]
贡献于非洲爪蟾神经管闭合的组织之间细胞刚度的不同
Makoto Suzuki,Naoko Yasue,Naoto Ueno
Makoto Suzuki
During the formation of the neural tube, the primordium of the vertebrate central nervous system, the actomyosin activity of cells in different regions drives neural plate bending. However, how the stiffness of the neural plate and surround...