Regeneration of Lumbriculus variegatus requires post-amputation production of reactive oxygen species [0.03%]
活动氧在再生医蛭线虫再生中的作用
Freya R Beinart,Kathy Gillen
Freya R Beinart
Animals vary in their ability to replace body parts lost to injury, a phenomenon known as restorative regeneration. Uncovering conserved signaling steps required for regeneration may aid regenerative medicine. Reactive oxygen species (ROS) ...
The transmembrane protein TMEM196 controls cell proliferation and determines the floor plate cell lineage [0.03%]
跨膜蛋白TMEM196调控细胞增殖并决定基板细胞谱系
Yumi Matsumoto,Seiichi Tamaru,Xing Chen et al.
Yumi Matsumoto et al.
The neural tube, the embryonic precursor to the vertebrate central nervous system, comprises distinct progenitor and neuronal domains, each with specific proliferation programs. In this study, we identified TMEM196, a novel transmembrane pr...
"Fly to New World": Meeting report of the 16th Japanese Drosophila research conference (JDRC16) [0.03%]
“飞向新世界”——第十六届日本果蝇研究会议(JDRC16)会议纪要
Haruka Yoshizawa,Erina Kuranaga
Haruka Yoshizawa
The 16th Japanese Drosophila Research Conference (JDRC16) was held at the Sendai International Center from September 17 to 19 2024. It had been 2 years since the last JDRC15 held in Nagoya. The conference brought together 231 researchers, i...
Early development of the calcified exoskeleton of the polyplacophoran mollusk, with insight into the evolutionary history of shell plates and spicules [0.03%]
多板纲软体动物钙化外骨骼的早期发育及外壳板和棘的进化历史的见解
Hiroki Yoshikawa,Yoshiaki Morino,Hiroshi Wada
Hiroki Yoshikawa
Recent molecular phylogenetic studies have raised two questions about the evolutionary history of the calcified exoskeleton of mollusks. The first question concerns the homology of the two types of skeleton: whether spicules and shell plate...
Sonic Hedgehog signaling regulates the optimal differentiation pace from early-stage mesoderm to cardiogenic mesoderm in mice [0.03%]
Sonic hedgehog信号调控小鼠早期体节中心血管前体细胞分化速率
Satoshi Inoue,Moe Nosetani,Yoshiro Nakajima et al.
Satoshi Inoue et al.
Sonic Hedgehog (Shh), encoding an extracellular signaling molecule, is vital for heart development. Shh null mutants show congenital heart disease due to left-right asymmetry defects stemming from functional anomaly in the midline structure...
Meeting report about self-organization in biology: Freiburg Spemann-Mangold Centennial Symposium [0.03%]
关于生物学中的自我组织的会议报告：弗莱堡斯佩曼-孟加尔百年研讨会
Satoshi Kuwana,Yuuri Yasuoka
Satoshi Kuwana
From September 16 to 19, 2024, an international symposium to celebrate the centennial of the discovery of the gastrula organizer by Hans Spemann and Hilde Mangold, was held at the University of Freiburg, Germany, where they studied embryolo...
A comparative approach to the microstructure in the carpus and tarsus in anurans [0.03%]
两栖动物腕足和跗跖骨微细结构的比较研究
Marissa Fabrezi,Julio César Cruz
Marissa Fabrezi
Despite the significant literature about morphological features of limb skeletons involved in tetrapod limb evolution, some questions about carpal and tarsal elements remain. In anurans, the ecomorphological and biomechanical approaches stu...
Effect of Cdk1 gene disruption on cell cycle progression in newt cells [0.03%]
新免细胞中Cdk1基因敲除对细胞周期进程的影响
Yuta Nakao,Kazuko Okamoto,Ichiro Tazawa et al.
Yuta Nakao et al.
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression, in conjunction with cyclins. The cyclin-CDK system is highly conserved among eukaryotes, and CDK1 is considered essential for progression through the M phase. How...
Novel function of Hox13 in regulating outgrowth of the newt hindlimb bud through interaction with Fgf10 and Tbx4 [0.03%]
Hox13通过与Fgf10和Tbx4的相互作用调控新蹄蛙后肢芽发育的新功能
Sayo Tozawa,Haruka Matsubara,Fumina Minamitani et al.
Sayo Tozawa et al.
5'Hox genes regulate pattern formation along the axes of the limb. Previously, we showed that Hoxa13/Hoxd13 double-mutant newts lacked all digits of the forelimbs during development and regeneration, showing that newt Hox13 is necessary for...
The polycomb protein complex interacts with GATA-6/PPARα to inhibit α-MHC expression [0.03%]
Polycomb蛋白复合体与GATA-6/PPARα相互作用抑制α-MHC的表达
Fei-Fei Dai,Jing Chen,Zhen Ma et al.
Fei-Fei Dai et al.
Transcription factors collaborate with epigenetic regulatory factors to orchestrate cardiac differentiation for heart development, but the underlying mechanism is not fully understood. Here, we report that GATA-6 induces cardiac differentia...