Sonic Hedgehog signaling regulates the optimal differentiation pace from early-stage mesoderm to cardiogenic mesoderm in mice [0.03%]
Sonic hedgehog信号调控小鼠早期体节中心血管前体细胞分化速率
Satoshi Inoue,Moe Nosetani,Yoshiro Nakajima et al.
Satoshi Inoue et al.
Sonic Hedgehog (Shh), encoding an extracellular signaling molecule, is vital for heart development. Shh null mutants show congenital heart disease due to left-right asymmetry defects stemming from functional anomaly in the midline structure...
Meeting report about self-organization in biology: Freiburg Spemann-Mangold Centennial Symposium [0.03%]
关于生物学中的自我组织的会议报告：弗莱堡斯佩曼-孟加尔百年研讨会
Satoshi Kuwana,Yuuri Yasuoka
Satoshi Kuwana
From September 16 to 19, 2024, an international symposium to celebrate the centennial of the discovery of the gastrula organizer by Hans Spemann and Hilde Mangold, was held at the University of Freiburg, Germany, where they studied embryolo...
A comparative approach to the microstructure in the carpus and tarsus in anurans [0.03%]
两栖动物腕足和跗跖骨微细结构的比较研究
Marissa Fabrezi,Julio César Cruz
Marissa Fabrezi
Despite the significant literature about morphological features of limb skeletons involved in tetrapod limb evolution, some questions about carpal and tarsal elements remain. In anurans, the ecomorphological and biomechanical approaches stu...
Effect of Cdk1 gene disruption on cell cycle progression in newt cells [0.03%]
新免细胞中Cdk1基因敲除对细胞周期进程的影响
Yuta Nakao,Kazuko Okamoto,Ichiro Tazawa et al.
Yuta Nakao et al.
Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression, in conjunction with cyclins. The cyclin-CDK system is highly conserved among eukaryotes, and CDK1 is considered essential for progression through the M phase. How...
Novel function of Hox13 in regulating outgrowth of the newt hindlimb bud through interaction with Fgf10 and Tbx4 [0.03%]
Hox13通过与Fgf10和Tbx4的相互作用调控新蹄蛙后肢芽发育的新功能
Sayo Tozawa,Haruka Matsubara,Fumina Minamitani et al.
Sayo Tozawa et al.
5'Hox genes regulate pattern formation along the axes of the limb. Previously, we showed that Hoxa13/Hoxd13 double-mutant newts lacked all digits of the forelimbs during development and regeneration, showing that newt Hox13 is necessary for...
The polycomb protein complex interacts with GATA-6/PPARα to inhibit α-MHC expression [0.03%]
Polycomb蛋白复合体与GATA-6/PPARα相互作用抑制α-MHC的表达
Fei-Fei Dai,Jing Chen,Zhen Ma et al.
Fei-Fei Dai et al.
Transcription factors collaborate with epigenetic regulatory factors to orchestrate cardiac differentiation for heart development, but the underlying mechanism is not fully understood. Here, we report that GATA-6 induces cardiac differentia...
Shunsuke Yaguchi
Shunsuke Yaguchi
Quantitative in toto live imaging analysis of apical nuclear migration in the mouse telencephalic neuroepithelium [0.03%]
小鼠脑神经上皮顶侧核迁移的定量全景活体图谱分析
Tsukasa Shimamura,Takaki Miyata
Tsukasa Shimamura
In the embryonic neuroepithelium (NE), neural progenitor cells undergo cell cycle-dependent interkinetic nuclear migration (IKNM) along the apicobasal axis. Extensive IKNM supports increasing cell production rates per unit apical surface, a...
Labeling and sorting of avian primordial germ cells utilizing Lycopersicon Esculentum lectin [0.03%]
利用番茄 Lectin 识别和分选禽类生殖细胞干细胞研究进展
Hiroko Iikawa,Aika Nishina,Mizuki Morita et al.
Hiroko Iikawa et al.
Avian species are essential resources for human society, with their preservation and utilization heavily dependent on primordial germ cells (PGCs). However, efficient methods for isolating live PGCs from embryos remain elusive in avian spec...
Transition from fetal to postnatal state in the heart: Crosstalk between metabolism and regeneration [0.03%]
心脏从胎儿到出生后的转变：代谢与再生的相互作用
Tai Sada,Wataru Kimura
Tai Sada
Cardiovascular disease is the leading cause of mortality worldwide. Myocardial injury resulting from ischemia can be fatal because of the limited regenerative capacity of adult myocardium. Mammalian cardiomyocytes rapidly lose their prolife...