Mapping Single-Cell Mechanics in the Early Embryogenesis of Xenopus laevis Using Atomic Force Microscopy [0.03%]
利用原子力显微镜绘制非洲爪蟾胚胎早期单细胞力学图谱
Miki Yamamoto,Takayoshi Yamamoto,Takahiro Kotani et al.
Miki Yamamoto et al.
During early embryonic development, cells undergo rapid cleavage divisions accompanied by morphological changes driven by mechanical cues. However, the spatiotemporal mechanics of regulative embryonic cells remains poorly understood. Here, ...
C-Terminal End of Gli3 Is Critical for Functional Protein Synthesis and Gli3-Dependent Anatomical Development [0.03%]
Gli3羧基末端端对于功能性蛋白质合成及Gli3依赖性解剖学发育至关重要
Nguyen Thi My Trinh,Sota Ikeda,Ako Agata et al.
Nguyen Thi My Trinh et al.
The GLI3 gene, a pivotal component of the hedgehog (HH) signaling pathway, plays a fundamental role in the development and patterning of various body structures, including the brain and limbs. Mutations in the GLI3 gene, particularly in the...
Tumor Development in Ulcerative Colitis: Perspectives From Biomechanical Characteristics [0.03%]
溃疡性结肠炎肿瘤发生的生物力学特征分析
Hirotaka Tao
Hirotaka Tao
Throughout our lifespan, sustaining orderly morphological structures for ensuring proper functioning of organs is imperative. Among these structures, the extracellular matrix (ECM) plays a pivotal role in sustaining organ and tissue homeost...
Lineage Analysis of Pallial Subdivision-Derived Cells in the Developing Chick Pallium [0.03%]
鸡壳瓣发育过程中来源于壳瓣分化的细胞的系谱分析
Kyosuke Wada,Ryoka Katayama,Illia Aota et al.
Kyosuke Wada et al.
The avian pallium is comprised of several nuclear regions (four main areas) and differs significantly from the mammalian telencephalon, which is a six-layered structure. Although it is known that cells with identical features at the gene ex...
Hox3 Is Required for Post-Metamorphic Heart Development in Adult Ciona [0.03%]
HOX3基因对于尾芽后期环节心脏发育的必要性研究——以海鞘成体为模型
Ryota Saito,Tatsuki Hyodo,Nene Kamakura et al.
Ryota Saito et al.
Although the differentiation of cardiac progenitors during embryogenesis has been characterized in detail in the ascidian Ciona robusta, heart development after metamorphosis remains unclear. The sub-terminal regions at both ends of the Cio...
Astacin Metalloproteinase PpMC5 of Mesenchyme Cells Regulates Epithelial Cell Proliferation and Survival to Promote Starfish Larval Development [0.03%]
基质细胞源的金属蛋白酶PpMC5通过调控上皮细胞增殖和存活促进海星幼虫发育
Yamato Okura,Kaichiro Sawada,Jun Gojobori et al.
Yamato Okura et al.
The simple, triploblastic, epithelial body structure of the Patiria pectinifera starfish larva contains one mesenchyme cell type distributed across the blastocoel. In this study, we elucidated the role of a novel astacin metalloproteinase, ...
Expression of hox Genes and Genes Related to Limb Development During the Homeotic Transformation of Tails Into Limbs Induced by Vitamin A in the Anuran Rana ornativentris [0.03%]
维生素A诱导蛙类尾部向 limbs发生改变过程中HOX基因及肢体发育相关基因的表达模式研究
Sho Morioka,Yoshio Yaoita,Keisuke Nakajima et al.
Sho Morioka et al.
Anuran tadpoles regenerate their tails after amputation. However, when vitamin A is administered, some anuran species such as Rana ornativentris occasionally form ectopic limbs instead of tail. Few analyses of this phenomenon at the molecul...
Fate and Specification of the Ventral Endoderm in and Outside the Foregut of the Avian Embryo at 9-12 Somite Stage [0.03%]
第9～12背节期鸡胚胎腹内胚层在原肠和前肠的命运及特征研究
Susumu Matsushita,Koko Urase
Susumu Matsushita
The fate and specification of the endoderm lining the ventral foregut and outside the foregut cranial to the anterior intestinal portal of the 9-12 somite stage avian embryo were analyzed to determine whether this endoderm was specified acc...
Roles of Extracellular Superoxide Dismutase in Regulating Cell Migration and Vesicle Trafficking in Dictyostelium and Mammalian Cells [0.03%]
胞外超氧化物歧化酶在调控Dictyostelium和哺乳动物细胞迁移及囊泡运输中的作用
Lou W Kim
Lou W Kim
Superoxide dismutases (SODs) are key regulators of reactive oxygen species (ROS) and redox balance. Although intracellular SODs have been extensively studied, growing attention has been directed toward understanding the roles of extracellul...
Integrating Tissue and Cytoplasmic Rigidity Transitions During Morphogenesis [0.03%]
发育过程中组织和细胞质刚度转变的整合
Sameer Thukral,Bipasha Dey,Yu-Chiun Wang
Sameer Thukral
Multicellular organisms generate organizational complexity through morphogenesis, in which mechanical forces orchestrate the movements and deformations of cells and tissues, while chemical signals regulate the molecular events that generate...