Development of a heat-stable alkaline phosphatase reporter system for cis-regulatory analysis and its application to 3D digital imaging of Xenopus embryonic tissues [0.03%]
热稳定碱性磷酸酶报告系统的开发及其在非洲爪蟾胚胎组织3D数字成像中的应用分析
Kiyo Sakagami,Takeshi Igawa,Kaori Saikawa et al.
Kiyo Sakagami et al.
Xenopus is one of the essential model systems for studying vertebrate development. However, one drawback of this system is that, because of the opacity of Xenopus embryos, 3D imaging analysis is limited to surface structures, explant cultur...
Genomic screening of fish-specific genes in gnathostomes and their functions in fin development [0.03%]
脊椎动物中鱼类特异基因的基因组筛选及其在鱼鳍发育中的功能
Hidehiro Kudoh,Sayuri Yonei-Tamura,Gembu Abe et al.
Hidehiro Kudoh et al.
In this study, we comprehensively searched for fish-specific genes in gnathostomes that contribute to development of the fin, a fish-specific trait. Many previous reports suggested that animal group-specific genes are often important for gr...
Cell adhesion and actin dynamics factors promote axonal extension and synapse formation in transplanted Drosophila photoreceptor cells [0.03%]
细胞黏附和肌动蛋白动力学因子促进移植的果蝇光感受器细胞轴突延伸和突触形成
Riku Iwanaga,Nagisa Yahagi,Satoko Hakeda-Suzuki et al.
Riku Iwanaga et al.
Vision is formed by the transmission of light stimuli to the brain through axons extending from photoreceptor cells. Damage to these axons leads to loss of vision. Despite research on neural circuit regeneration through transplantation, ach...
Evolutionarily conserved roles of foxg1a in the developing subpallium of zebrafish embryos [0.03%]
狐疑果蝇基因foxg1a在斑马鱼胚胎发育的下底丘脑中进化保守的作用
Koto Umeda,Kaiho Tanaka,Gazlima Chowdhury et al.
Koto Umeda et al.
The vertebrate telencephalic lobes consist of the pallium (dorsal) and subpallium (ventral). The subpallium gives rise to the basal ganglia, encompassing the pallidum and striatum. The development of this region is believed to depend on Fox...
FGF-stimulated tendon cells embrace a chondrogenic fate with BMP7 in newt tissue culture [0.03%]
在新的组织培养中，FGF刺激的腱细胞与BMP7结合呈现软骨生成的命运
Nao Sugiura,Kiyokazu Agata
Nao Sugiura
Newts can regenerate functional elbow joints after amputation at the joint level. Previous studies have suggested the potential contribution of cells from residual tendon tissues to joint cartilage regeneration. A serum-free tissue culture ...
Dissection of N-deacetylase and N-sulfotransferase activities of NDST1 and their effects on Wnt8 distribution and signaling in Xenopus embryos [0.03%]
NDST1的N-脱乙酰酶和N-硫酸转移酶活性的剖析及其对非洲爪蟾胚胎中Wnt8分布和信号传导的影响
Minako Suzuki,Shinji Takada,Yusuke Mii
Minako Suzuki
Wnt is a family of secreted signaling proteins involved in the regulation of cellular processes, including maintenance of stem cells, carcinogenesis, and cell differentiation. In the context of early vertebrate embryogenesis, graded distrib...
Membrane molecule bouncer regulates sperm binding activity in immature oocytes in the viviparous teleost species Poecilia reticulata (guppy) [0.03%]
膜分子弹出器调节活产鲤科动物Poecilia reticulata（孔雀鱼）不成熟卵母细胞中的精子结合活性
Junki Yoshida,Yuki Tajika,Kazuko Uchida et al.
Junki Yoshida et al.
Generally, in vertebrates, the first step toward fertilization is the ovulation of mature oocytes, followed by their binding to sperm cells outside of the ovary. Exceptionally, the oocytes of poeciliid fish are fertilized by sperm cells wit...
Macrophages enhance regeneration of lateral line neuromast derived from interneuromast cells through TGF-β in zebrafish [0.03%]
巨噬细胞通过TGF-β促进斑马鱼侧线神经节内神经节细胞的再生
Wei-Lin Hsu,Yu-Chi Lin,Meng-Ju Lin et al.
Wei-Lin Hsu et al.
Macrophages play a pivotal role in the response to injury, contributing significantly to the repair and regrowth of damaged tissues. The external lateral line system in aquatic organisms offers a practical model for studying regeneration, f...
Involvement of nr2f genes in brain regionalization and eye development during early zebrafish development [0.03%]
nr2f基因在斑马鱼早期发育过程中的脑区化和眼发育中的作用
Gazlima Chowdhury,Koto Umeda,Takero Ohyanagi et al.
Gazlima Chowdhury et al.
Nuclear receptor subfamily 2 group F (Nr2f) proteins are essential for brain development in mice, but little is known about their precise roles and their evolutionary diversification. In the present study, the expression patterns of major n...
Efficient detection of single nucleotide variants in targeted genomic loci [0.03%]
靶向基因组位点中单核苷酸变异的高效检测
Ryota Sone,Saori Fujimaki,Atsuo Kawahara
Ryota Sone
Single nucleotide variants (SNVs), including single nucleotide polymorphisms, are often associated with morphological and/or physiological abnormalities in various organisms. Targeted genomic DNA can be amplified and directly sequenced to d...