FGF-stimulated tendon cells embrace a chondrogenic fate with BMP7 in newt tissue culture [0.03%]
在新的组织培养中,FGF刺激的腱细胞与BMP7结合呈现软骨生成的命运
Nao Sugiura,Kiyokazu Agata
Nao Sugiura
Newts can regenerate functional elbow joints after amputation at the joint level. Previous studies have suggested the potential contribution of cells from residual tendon tissues to joint cartilage regeneration. A serum-free tissue culture ...
Dissection of N-deacetylase and N-sulfotransferase activities of NDST1 and their effects on Wnt8 distribution and signaling in Xenopus embryos [0.03%]
NDST1的N-脱乙酰酶和N-硫酸转移酶活性的剖析及其对非洲爪蟾胚胎中Wnt8分布和信号传导的影响
Minako Suzuki,Shinji Takada,Yusuke Mii
Minako Suzuki
Wnt is a family of secreted signaling proteins involved in the regulation of cellular processes, including maintenance of stem cells, carcinogenesis, and cell differentiation. In the context of early vertebrate embryogenesis, graded distrib...
Membrane molecule bouncer regulates sperm binding activity in immature oocytes in the viviparous teleost species Poecilia reticulata (guppy) [0.03%]
膜分子弹出器调节活产鲤科动物Poecilia reticulata(孔雀鱼)不成熟卵母细胞中的精子结合活性
Junki Yoshida,Yuki Tajika,Kazuko Uchida et al.
Junki Yoshida et al.
Generally, in vertebrates, the first step toward fertilization is the ovulation of mature oocytes, followed by their binding to sperm cells outside of the ovary. Exceptionally, the oocytes of poeciliid fish are fertilized by sperm cells wit...
Macrophages enhance regeneration of lateral line neuromast derived from interneuromast cells through TGF-β in zebrafish [0.03%]
巨噬细胞通过TGF-β促进斑马鱼侧线神经节内神经节细胞的再生
Wei-Lin Hsu,Yu-Chi Lin,Meng-Ju Lin et al.
Wei-Lin Hsu et al.
Macrophages play a pivotal role in the response to injury, contributing significantly to the repair and regrowth of damaged tissues. The external lateral line system in aquatic organisms offers a practical model for studying regeneration, f...
Involvement of nr2f genes in brain regionalization and eye development during early zebrafish development [0.03%]
nr2f基因在斑马鱼早期发育过程中的脑区化和眼发育中的作用
Gazlima Chowdhury,Koto Umeda,Takero Ohyanagi et al.
Gazlima Chowdhury et al.
Nuclear receptor subfamily 2 group F (Nr2f) proteins are essential for brain development in mice, but little is known about their precise roles and their evolutionary diversification. In the present study, the expression patterns of major n...
Efficient detection of single nucleotide variants in targeted genomic loci [0.03%]
靶向基因组位点中单核苷酸变异的高效检测
Ryota Sone,Saori Fujimaki,Atsuo Kawahara
Ryota Sone
Single nucleotide variants (SNVs), including single nucleotide polymorphisms, are often associated with morphological and/or physiological abnormalities in various organisms. Targeted genomic DNA can be amplified and directly sequenced to d...
Hung-Yu Shih,Quentin Raas,Joshua L Bonkowsky
Hung-Yu Shih
Inherited leukodystrophies are genetic disorders characterized by abnormal white matter in the central nervous system. Although individually rare, there are more than 400 distinct types of leukodystrophies with a cumulative incidence of 1 i...
Correction to "Mosaic gene expression analysis of semaphorin-plexin interactions in Caenorhabditis elegans using the IR-LEGO single-cell gene induction system" [0.03%]
《使用IR-LEGO单细胞基因诱导系统分析秀丽隐杆线虫中丝束蛋白-plexin相互作用的马赛克基因表达》一文的勘误
Published Erratum
Development, growth & differentiation. 2024 Jan;66(1):101. DOI:10.1111/dgd.12903 2024
Transcription factor Tcf21 modulates urinary bladder size and differentiation [0.03%]
转录因子Tcf21调节尿膀胱的大小和分化
Elizabeth A Mann,Melissa S Mogle,Joo-Seop Park et al.
Elizabeth A Mann et al.
Urinary bladder organogenesis requires coordinated cell growth, specification, and patterning of both mesenchymal and epithelial compartments. Tcf21, a gene that encodes a helix-loop-helix transcription factor, is specifically expressed in ...
Gene correction and overexpression of TNNI3 improve impaired relaxation in engineered heart tissue model of pediatric restrictive cardiomyopathy [0.03%]
TNNI3的基因校正和过表达可改善儿童限制性心肌病工程心脏组织模型中的松弛障碍
Moyu Hasegawa,Kenji Miki,Takuji Kawamura et al.
Moyu Hasegawa et al.
Research on cardiomyopathy models using engineered heart tissue (EHT) created from disease-specific induced pluripotent stem cells (iPSCs) is advancing rapidly. However, the study of restrictive cardiomyopathy (RCM), a rare and intractable ...