Clinical Analysis of Pulmonary Nontuberculous Mycobacterial Infection in Patients With Pre-Existing Stage II-IV Lung Cancer [0.03%]
II-IV期肺癌患者合并肺非结核分枝杆菌感染的临床分析
Juan Li,Junsheng Fan,Zhili Tan et al.
Juan Li et al.
Immune checkpoint inhibitors (ICIs) targeting programmed cell death-1 (PD-1) and programmed cell death ligand-1 (PD-L1) have improved cancer outcomes but can induce immune-related adverse events, including mycobacterial infections. This stu...
Mapping Nutrition and Tuberculosis Research: Insights From Bibliometric Perspective [0.03%]
基于文献计量学视角的营养与结核病研究图谱分析
Chenqi Li,Biao Gao,Hongmei Xiao et al.
Chenqi Li et al.
Background: Malnutrition and tuberculosis form a mutually reinforcing vicious cycle. While nutritional interventions are crucial for TB management, the knowledge structure and research frontiers remain insufficiently char...
Gold-Containing Compound Auranofin Ameliorates 6-OHDA Induced Neurotoxicity in Rats: Via Targeting PI3K/Akt/GSK-3β Signalling [0.03%]
金化合物Auranofin通过靶向PI3K/Akt/GSK-3β信号途径改善6-HDA诱导的大鼠神经毒性
Divya Soni,Manjinder Singh,Yogesh Garg et al.
Divya Soni et al.
The prevalence of parkinsonism is increasing worldwide, not only in age groups but now becoming a favourite of adults. As the onset is increasing in developed and underdeveloped countries, the current therapy lacks a permanent cure. Therefo...
RETRACTION: An MSC Bone-Homing Compound, Rab001, Increases Bone Mass and Reduces the Incidence of Osteonecrosis in a Glucocorticoid-Induced Osteonecrosis Mouse Model [0.03%]
撤回：一种间充质干细胞导向化合物Rab001通过增加骨量来减少糖皮质激素诱导的骨坏死小鼠模型中的骨坏死发生率
M. Jiang, L. Liu, X. Xiang, R. Liang, X. Qin, J. Zhao, and Q. Wei, "An MSC Bone-Homing Compound, Rab001, Increases Bone Mass and Reduces the Incidence of Osteonecrosis in a Glucocorticoid-Induced Osteonecrosis Mouse Model," Clinical and Exp...
Prevalence and Associated Factors of Anxiety and Depression in Lung Cancer Patients [0.03%]
肺癌患者的焦虑和抑郁的患病率及其影响因素分析
Xinran Gao,Maoying Guan,Bing Bo et al.
Xinran Gao et al.
Purpose: Given the prevalence of anxiety and depression amongst lung cancer patients in China, it is critical to identify potential factors contributing to these symptoms to improve future treatment strategies. However, c...
PACAP Inhibits TNF-α- Induced Senescence in Primary Chondrocytes by SIRT3: An Implication in Osteoarthritis [0.03%]
胰高血糖素样肽通过SIRT3途径抑制软骨细胞衰老：对关节炎的启示
Xuewu Zhou,Kangquan Shou,Hao Yao
Xuewu Zhou
Osteoarthritis (OA) is a degenerative joint disease closely associated with aging, in which chondrocyte senescence plays a critical role in cartilage degradation. Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide ...
Kaempferol Suppresses Mesothelial-Mesenchymal Transition and Attenuates Postoperative Peritoneal Adhesions by Blocking the TNF-α/COX2 Signalling Pathway [0.03%]
山柰酚通过抑制TNF-α/COX2信号通路干预腹膜间皮细胞上皮间质转化及术后粘连形成
Li Zhang,Gan Li,Yiwei Ren et al.
Li Zhang et al.
Postoperative peritoneal adhesion (PA) formation is a common complication after abdominal surgery and can result in various severe outcomes. Inflammation and fibrosis are important processes in PA formation. The effectiveness of kaempferol ...
Novel Semisynthetic Derivative of Dehydrozingerone (DHZ-15) Modulates Lipopolysaccharide-Stimulated Macrophages by Targeting the NF-κB/p65 Pathway and In Vivo Evaluation in a Sepsis BALB/c Model [0.03%]
新型半合成去氢姜酚衍生物DHZ-15通过靶向NF-κB/p65途径调节脂多糖刺激的巨噬细胞及其在BALB/c败血症小鼠模型中的体内评价研究
Irfan Qasam,Shah Nawaz,Chetan Kumar et al.
Irfan Qasam et al.
Natural products and their semisynthetic derivatives possess tremendous medicinal properties and have the potential to modulate the immune system, providing new therapeutic options for drug development. In this study, we evaluated Dehydrozi...
Recent Advances in Targeted Protein Degradation Molecular Glues as Anticancer Drugs [0.03%]
靶向蛋白质降解分子胶的最新研究进展作为抗癌药物
Yulin Shen,Wen Wen,Luoyang Chen et al.
Yulin Shen et al.
Molecular glues have emerged as a novel class of targeted protein degraders with broad potential in cancer therapy. By inducing proximity between E3 ubiquitin ligases and oncogenic proteins, these agents activate the ubiquitin-proteasome sy...
Pyroptosis-Mediated Antitumor Activity of Cinobufagin in Non-Small Cell Lung Cancer [0.03%]
灯盏生脉药效成分雷公藤内酯酮通过调节肿瘤细胞焦亡抑制非小细胞肺癌血管生成及转移的研究
Ying Chen,Feng Hu,Jiahuan Lu et al.
Ying Chen et al.
This study aims to investigate the therapeutic efficacy and molecular mechanism of cinobufagin in non-small cell lung cancer (NSCLC) via pyroptosis induction. Bronchial epithelial cells and NSCLC cell lines were treated with gradient concen...