High Glycemic Variability as a Risk Factor for CKD Progression in Type 2 Diabetes with Mild-to-Moderate Kidney Dysfunction [0.03%]
高血糖波动通过促进2型糖尿病肾功能轻至中度受损患者肾脏病进展发挥作用
Taro Saigusa,Kentaro Watanabe,Masahiro Takubo et al.
Taro Saigusa et al.
This study retrospectively evaluates the risk of chronic kidney disease (CKD) progression in patients with type 2 diabetes and mild-to-moderate reduction in the estimated glomerular filtration rate (eGFR).Sixty-six patients with type 2 diab...
Effects of Empagliflozin in Heart Failure Patients with Type 2 Diabetes: A Biomarker Perspective [0.03%]
恩格列净对2型糖尿病心力衰竭患者的影响：生物标志物视角
Asmaa Elrakaybi,Qian Zhou,Günter Päth et al.
Asmaa Elrakaybi et al.
Sodium-glucose co-transporter inhibitors significantly reduce cardiovascular mortality, hospitalization for heart failure, and improve renal outcomes regardless of diabetes status. This study investigated the effect of empagliflozin on plas...
Sitagliptin does not interfere with VEGF-A signaling in retinal endothelial cells in vitro [0.03%]
西格列汀体外不干扰视网膜内皮细胞的VEGF-A信号通路
Lucian Amthor,Anja Jaeckle,Juergen Kampmeier et al.
Lucian Amthor et al.
Sitagliptin, an inhibitor of dipeptidyl peptidase-4 widely used in type 2 diabetes therapy, impairs the barrier formed by retinal endothelial cells (REC) during prolonged exposure. Because diabetic macular edema is treated with inhibitors o...
Responses of Regulator of G Protein Signaling Proteins and Circadian Clock Components to Sustained Depolarization-Induced Dedifferentiation in MIN6 β-Cells [0.03%]
MIN6 β细胞去分化过程中RGS蛋白和生物钟组分的响应研究
Satoshi Okano,Yu Sasaki,Akira Yasui et al.
Satoshi Okano et al.
Background: Regulators of G protein signaling (RGSs) are key modulators of β-cell function and stress adaptation. Similarly, circadian clock components are intricately implicated in the regulation of insulin secretion an...
The impact of Semaglutide on weight loss and inflammation in people with HIV. An observational prospective study in Greek population [0.03%]
塞马鲁肽对HIV患者体重减轻和炎症的影响。希腊人群的观察性前瞻性研究
Vasileios Petrakis,Petros Rafailidis,Maria Panopoulou et al.
Vasileios Petrakis et al.
Introduction: The existing literature on the effects of semaglutide in people with HIV (PWH) and diabetes mellitus remains limited. The aim of the present study is to evaluate the effect of semaglutide on weight control a...
Differential Effects of High Methionine Diet on Biochemical Parameters in Normal and Diabetic Rat Models [0.03%]
高甲硫氨酸饮食对正常和糖尿病大鼠生化参数影响的差异性研究
Yongwei Jiang,Meimei Zhao,Mo Li et al.
Yongwei Jiang et al.
This study investigated the organ-specific effects of a high-methionine (HM) diet in streptozotocin (STZ)-induced diabetic rats, focusing on hepatic and renal metabolic adaptations. Male Wistar rats were divided into four groups (n=8/group)...
Acute cold exposure improves glucose tolerance and induces beta-cell secretion response linked to lipid utilization in young male with obesity [0.03%]
急性寒冷暴露可改善肥胖年轻男性的葡萄糖耐量并诱导与脂质利用相关的β细胞分泌反应
Rodrigo Chamorro,Beatrice Bertozzi,Jenny Backhaus et al.
Rodrigo Chamorro et al.
Aims: In lean humans, cold-activated brown adipose tissue (BAT) is associated with improved insulin sensitivity and lipid metabolism. Metabolic consequences of acute cold exposure in obesity are less well characterized. W...
An Insight into the Therapeutic Potential of Phytobioactives for Diabetic Neuropathy [0.03%]
植物生物活性物质治疗糖尿病神经病变潜力的研究进展
Asif Eqbal,Poonam Kushwaha,Sanjay Kumar et al.
Asif Eqbal et al.
Diabetic neuropathy, a debilitating complication of diabetes, arises from chronic hyperglycemia-induced inflammation and oxidative stress, leading to progressive nerve damage. Current therapeutic strategies often focus on symptomatic relief...
Balance impairment in diabetic peripheral neuropathy: Where do we stand? [0.03%]
糖尿病外周神经病患者平衡障碍的研究进展与未来方向
Dimitrios Pantazopoulos,Evanthia Gouveri,Dimitrios Papazoglou et al.
Dimitrios Pantazopoulos et al.
Diabetic peripheral neuropathy (DPN) is one of the most frequent complications of diabetes mellitus (DM). The aim of this brief narrative review was to discuss the relationship between DPN and balance impairment. DPN may alter movement perc...
The Effect of Radiological Imaging Reports in Clinical Decision-Making in the Management of Adrenal Incidentaloma [0.03%]
影像学报告在肾上腺意外瘤管理临床决策中的作用
Puren Gökbulut,Cagatay Emir Onder,Serife Mehlika Kuskonmaz
Puren Gökbulut
To assess the necessity of additional imaging by comparing the characteristics of adrenal lesions incidentally detected on abdominal, stone protocol, and chest computed tomography (CT) with those obtained from a second imaging modality spec...