Management of Invasive Pulmonary Aspergillosis in Intensive Care Units: Guidelines From the Fungal Infection Network of Switzerland (FUNGINOS) [0.03%]
瑞士真菌感染网络(FUNGINOS)关于重症监护病房侵袭性肺曲霉病诊疗的指导意见
F Lamoth,W C Albrich,S Ragozzino et al.
F Lamoth et al.
Invasive pulmonary aspergillosis (IPA) is increasingly recognised in intensive care units (ICU) affecting not only patients with classical immunosuppressive conditions but also other severely ill patients, including those with respiratory v...
Practice Guideline
Mycoses. 2025 Nov;68(11):e70132. DOI:10.1111/myc.70132 2025
Candida albicans Enhances Protease Activity and Activates MyD88-Dependent IL-1β Production in Human Keratinocytes [0.03%]
白色念珠菌增强人类角质形成细胞蛋白酶活性并激活MyD88依赖性IL-1β生成
Jingyi Wang,Neil A R Gow,Matthew G Brewer
Jingyi Wang
Background: Atopic dermatitis (AD) is a common chronic skin disorder characterised by a highly inflamed local environment and elevated epidermal proteolytic activity. Changes in the skin mycobiome have been observed in th...
Global Burden of Fungal Skin Diseases and Future Projections: An Analysis of the 2021 Global Burden of Disease Study [0.03%]
2021年全球疾病负担研究中的全球皮肤真菌病疾病负担及未来预测分析
Shao-Jie Chen,Song Chen,Ye Wang
Shao-Jie Chen
Background: The global prevalence and incidence of fungal skin diseases continue to rise due to population ageing, urbanisation and environmental changes, posing a significant public health challenge. These infections are...
The First Isolation of Multiple Antifungal-Drug-Resistant Trichophyton Rubrum in China and the Novel Resistance Mechanism [0.03%]
中国首次分离出多重抗真菌药物耐药的红色毛癣菌及新的耐药机制
Ge Song,Wenting Xie,Xue Kong et al.
Ge Song et al.
Objectives: This study reports the first isolation of a multidrug-resistant Trichophyton rubrum strain in China, characterizing its drug resistance profile and mechanisms. ...
Case Reports
Mycoses. 2025 Nov;68(11):e70128. DOI:10.1111/myc.70128 2025
In Vitro Activity of Nitroxoline (5-Nitro-8-Hydroxyquinoline) Against Aspergillus Species [0.03%]
5-硝基-8-羟基喹啉对曲霉属的体外活性
Ada Hoffmann,Oliver A Cornely,Jana Vonhoegen et al.
Ada Hoffmann et al.
Background: Nitroxoline is an old antibiotic currently approved for the treatment of uncomplicated urinary tract infections. Its mode of action is based on the chelation of bivalent cations, such as zinc. ...
Diagnostic Performance of a PCR-Based Approach for the Diagnosis of Dermatomycosis [0.03%]
一种PCR方法诊断皮真菌病的诊断性能研究
Stephan Steixner,Stefan Fuchs,Roya Vahedi-Shahandashti et al.
Stephan Steixner et al.
Background: Dermatomycoses, superficial fungal infections of the skin, hair and nails, are among the most common dermatological conditions worldwide. Rapid and accurate diagnosis is essential, particularly in light of eme...
Tanja Roehmer Wriedt,Lise Heilmann Jensen,Abdullah Mansouri et al.
Tanja Roehmer Wriedt et al.
Background: The prevalence of onychomycosis among children is suspected to be increasing. The current global prevalence of paediatric onychomycosis ranges from 0% to 7.7%. Clinical observations in Denmark suggest the same...
Efficacy and Safety of Rezafungin Versus Caspofungin for the Treatment of Candidemia and Invasive Candidiasis in a China Cohort of a Double-Blind, Randomised, Phase 3 Trial (ReSTORE China) [0.03%]
瑞左康唑与卡泊芬净治疗中国念珠菌血症和侵袭性念珠菌病患者的疗效和安全性：一项双盲、随机、III期试验（ReSTORE China）
Haihui Huang,Sizhou Feng,Yunsong Yu et al.
Haihui Huang et al.
Background: The global double-blind, randomised, Phase 3 ReSTORE trial (NCT03667690) demonstrated noninferiority of rezafungin versus caspofungin for all-cause mortality at Day 30 and global cure at Day 14 in patients wit...
Clinical Trial
Mycoses. 2025 Nov;68(11):e70122. DOI:10.1111/myc.70122 2025
Analysis of Susceptibility and Drug Resistance of Antifungal Agents in Aspergillosis and Mucormycosis Patients: A Systematic Review [0.03%]
侵袭性曲霉病和毛霉病患者抗真菌药物敏感性和耐药性的系统评价及meta分析
Yinggai Song,Paul E Verweij,Jochem B Buil et al.
Yinggai Song et al.
Objectives: To evaluate the susceptibility and resistance of Aspergillus and Mucorales isolates to antifungal agents. Methods: Studies ...
Performance of Quantitative PCR to Distinguish Pneumocystis jirovecii Pneumonia From Colonisation in Immunocompromised Patients [0.03%]
定量PCR鉴别免疫功能低下患者肺孢子菌肺炎和定植的临床价值
Sara Cederwall,Erik Ottander,David Björkhem et al.
Sara Cederwall et al.
Background: Pneumocystis jirovecii pneumonia (PCP) is a severe opportunistic infection affecting immunocompromised patients. Quantitative polymerase chain reaction (qPCR) is widely used for the detection of P. jirovecii i...