Efficacy Evaluation of Luliconazole-Loaded Nanostructured Lipid Carriers in Treatment-Resistant Dermatophytosis: A Randomized Clinical Trial [0.03%]
卢利康唑纳米结构脂质载体在难治性皮肤癣病治疗中的疗效评估：一项随机临床试验
Robab Ebrahimi Barogh,Seyed Ali Jeddi,Ghasem Rahmatpour Rokni et al.
Robab Ebrahimi Barogh et al.
Background: Dermatophytosis is a common superficial fungal infection that is increasingly complicated by terbinafine (TRB)-resistant strains, especially Trichophyton indotineae. Conventional antifungals often show limited...
The Global Antifungal Susceptibility Epidemiology of Trichophyton indotineae Indicating Voriconazole as an Alternative Therapy for Recalcitrant Dermatophytosis [0.03%]
三唑类抗真菌药治疗世界范围内的人类致病性皮肤丝状菌曲霉的新选择——伏立康唑：一项体外药敏流行病学研究
Ge Song,Wenting Xie,Xiaodong She et al.
Ge Song et al.
Background: The emergence of Trichophyton indotineae as a multidrug-resistant dermatophyte has challenged conventional therapeutic approaches for dermatophytosis, leading to a significant therapeutic dilemma. The absence ...
Prevalence and Clinical Implications of Aspergillus fumigatus Sensitisation in Chronic Obstructive Pulmonary Disease [0.03%]
曲霉菌致敏在慢性阻塞性肺疾病患者中的流行病学特征及其临床意义
Ying Luo,Yongchang Sun
Ying Luo
Chronic obstructive pulmonary disease (COPD) is a chronic airway inflammatory disease characterised by airway obstruction. Aspergillus fumigatus sensitisation represents a distinct, clinically relevant endotype in COPD. In recent years, stu...
Dermoscopic Features of Tinea Capitis in Korean Patients: Correlation With Clinical Subtypes, Age Groups and Causative Dermatophytes [0.03%]
韩国头癣患者的皮肤镜特征与临床亚型、年龄组和致病皮菌的相关性
Thi Quynh Trang Tran,Gwangil Kim,Hyun-Ji Ryu et al.
Thi Quynh Trang Tran et al.
Background: Tinea capitis (TC) presents with diverse clinical manifestations that may complicate diagnosis. Dermoscopy is a useful adjunctive tool, but data correlating dermoscopic findings with clinical and mycological c...
Impact of Concomitant Metamizole Treatment on the Exposure of Mould-Active Triazoles [0.03%]
伴用代谢唑治疗对霉菌活性三唑类药物暴露的影响
Dorian Vanneste,Ine De Booser,Kristina Nadrah et al.
Dorian Vanneste et al.
Aim: Metamizole is an analgesic drug with moderate cytochrome P450 (CYP) inductive properties. The antifungal triazoles are metabolized by several CYP enzymes, but the interaction with metamizole remains poorly described....
Histoplasma Urinary Antigen for the Diagnosis Histoplasmosis in Non-HIV Individuals [0.03%]
尿液抗原检测在非艾滋病患者播散性组织胞浆菌病诊断中的应用
João Nobrega de Almeida Jr,Tamara Harb Roca,Denise Dos Anjos Laurentis de Souza Campos et al.
João Nobrega de Almeida Jr et al.
Background: Histoplasmosis is an endemic mycosis in the Americas. While urinary Histoplasma antigen enzyme immunoassay testing (HAET) has been validated mainly in HIV-infected patients with disseminated disease, its perfo...
Invasive Fungal Infections After Intestine Transplantation: Epidemiology and Outcomes [0.03%]
肠移植后侵袭性真菌感染的流行病学和结局特征分析
Mayyadah H Alabdely,Jessica Lum,Blanca E Gonzalez et al.
Mayyadah H Alabdely et al.
Background: Invasive fungal infections (IFIs) represent a major complication after intestine transplantation, with reported incidence rates between 40% and 49%. These infections are associated with high morbidity and allo...
Clinical Patterns of Osteoarticular, Bone Marrow and Urogenital Paracoccidioidomycosis [0.03%]
关节骨、骨髓和泌尿生殖系统的变应性支气管肺曲霉病的临床表现模式
Wdson Luis Lima Kruschewsky,Mariane Cappellini Stricagnolo,Mônica Scarpelli Martinelli Vidal et al.
Wdson Luis Lima Kruschewsky et al.
Background: Paracoccidioidomycosis (PCM) is an endemic systemic mycosis in Latin America, classically characterized by pulmonary, mucosal and lymphatic involvement. Extrapulmonary manifestations affecting uncommon organs ...
Environmental Circulation of Aspergillus fumigatus With Reduced Susceptibility to Agricultural Triazole in Brazil: Clonal Dissemination of Potentially Resistant Genotypes [0.03%]
巴西环境中的农业三唑类抗性烟曲霉循环：潜在耐药基因型的克隆传播
Dality Keffelen de Barros Rodrigues,Manuel Leeuwerik,Balázs Brankovics et al.
Dality Keffelen de Barros Rodrigues et al.
Background: Aspergillus fumigatus resistance to triazole antifungals poses an increasing global health concern. Moreover, the cross-resistance between azole antifungal agents used in clinical settings and those applied in...
Integrated Genomic and Phenotypic Analyses Reveal Convergent Resistance Patterns in Clinical Candida tropicalis Isolates [0.03%]
整合基因组和表型分析揭示了临床Candida tropicalis分离株的多重耐药模式收敛性
Christy Chedraoui,Nour Fattouh,Setrida El Hachem et al.
Christy Chedraoui et al.
Background: The incidence of Candida tropicalis isolation is increasing in hospital settings. High azole resistance and mortality rates make it a pathogen that requires further analysis. ...