Reinstating and augmenting prospective audit and feedback for carbapenem stewardship: A quasi-experimental interrupted time-series study [0.03%]
碳青霉烯类药物管理的前瞻性审计和反馈的恢复与加强：准实验性中断时间序列研究
Yeonjin Son,Wongu Kang,Jiae Kim et al.
Yeonjin Son et al.
Background: At a tertiary hospital in Korea, carbapenem stewardship was suspended in March 2024 during a nationwide medical strike, leading to increased carbapenem use. In December 2024, stewardship activities were re-ini...
Clinical Course and Virologic Dynamics of Mpox During Tecovirimat Treatment: Prospective Multicenter Case Series in Japan [0.03%]
日本多家医疗机构进行的 tecovirimat 治疗马波沙星的临床病程和病毒动力学：前瞻性病例系列研究
Ayana Sakurai,Yutaro Akiyama,Shinichiro Morioka et al.
Ayana Sakurai et al.
Introduction: At the time of this study, no approved treatment for mpox was available in Japan, and data on the clinical course and virological changes during tecovirimat treatment were limited. ...
Concentration-dependent suppression of macrolide resistance in Mycobacterium avium by combination therapy: An improved in vitro time-kill assay and alveolar macrophage exposure-based pharmacokinetic/pharmacodynamic modeling study [0.03%]
浓度依赖性的联合疗法抑制分枝杆菌的巨菌素耐药性：一种改进的体外杀菌试验和基于肺泡巨噬细胞暴露的药物代谢动力学/药物效应动力学建模研究
Fumiya Watanabe,Yuta Morishige,Akio Aono et al.
Fumiya Watanabe et al.
Introduction: Macrolides are key drugs for treating Mycobacterium avium pulmonary disease, and combination chemotherapy is essential to preventing macrolide resistance. However, the concentrations of concomitant agents re...
Effectiveness of oral beta-lactam antibiotics in acute bacterial prostatitis: A retrospective study [0.03%]
口服β-内酰胺类抗生素治疗急性细菌性前列腺炎的疗效：一项回顾性研究
Yuichiro Nagase,Hidetoshi Nomoto,Shinya Tsuzuki et al.
Yuichiro Nagase et al.
Introduction: Fluoroquinolones (FQs) and trimethoprim-sulfamethoxazole (TMP-SMX) are first-line outpatient treatments for acute bacterial prostatitis (ABP). Owing to the increasing antimicrobial resistance and side effect...
Retroperitoneal infection associated with Streptococcus dysgalactiae subsp. equisimilis bacteremia and lower-extremity cellulitis: a case report [0.03%]
与链球菌血症和下肢蜂窝组织炎有关的腹膜后感染的病例报告
Tokuo Fujisawa
Tokuo Fujisawa
Streptococcus dysgalactiae subsp. equisimilis (SDSE) is an increasingly recognized β-hemolytic streptococcus causing invasive infections resembling those caused by Streptococcus pyogenes. Although SDSE bacteremia commonly arises from skin ...
Blood culture practices and J-SIPHE-defined bloodstream infection detection in Japanese acute-care hospitals: a nationwide database study [0.03%]
日本急性期医院的血培养实践及J-SIPHE定义的血液感染检测：一项全国数据库研究
Yuichi Shibata,Nobuhiro Asai,Mao Hagihara et al.
Yuichi Shibata et al.
Background: A quality indicator of ≥45 blood culture sets per 1000 patient-days (PDs) has been proposed for blood culture practice in Japan; however, supporting real-world evidence remains limited. This study evaluated b...
Efficacy and Safety of Oral Type II Topoisomerase Inhibitors Versus Ceftriaxone-Based Regimens for the Treatment of Gonorrhoea: A Systematic Review and Meta-Analysis of Randomised Controlled Trials [0.03%]
口服Ⅱ型拓扑异构酶抑制剂与头孢曲松为基础的方案治疗淋病疗效和安全性的系统评价和 meta 分析：基于随机对照试验的分析
Husni Mubarak Zainal,Ricardo Soares Guimarães,Tanika Sharma et al.
Husni Mubarak Zainal et al.
Background: Increasing incidence and accelerating antimicrobial resistance have made gonorrhoea a major global health challenge. As ceftriaxone stands as the only reliably effective option, the development of new therapie...
Malignant syphilis with presumed multifocal osteomyelitis in a patient with human immunodeficiency virus: A case report [0.03%]
一例人类免疫缺陷病毒感染患者的恶性梅毒并疑有骨髓炎：病例报告
Yuki Rikitake,Takeshi Kawaguchi,Chihiro Iwao et al.
Yuki Rikitake et al.
Malignant syphilis is a rare and aggressive form of secondary syphilis that occurs predominantly in individuals living with human immunodeficiency virus. Owing to its rarity, the prevalence of systemic involvement and the optimal therapeuti...
Occurrence of blaOXA-72 in a clinical isolate of carbapenem-resistant Acinetobacter pittii ST206 in Japan [0.03%]
日本一株碳青霉烯耐药的阿氏伯克霍尔德菌ST206临床分离株blaOXA-72携带报告
Taku Yamane,Tomohiro Denda,Tatsuya Natori et al.
Taku Yamane et al.
The development of carbapenem resistance in Acinetobacter spp., which are recognized as significant opportunistic pathogens, is of critical importance as it poses challenges to therapy and the control of healthcare-associated infections in ...
Imported cystic echinococcosis caused by Echinococcus granulosus sensu stricto genotype G3 in Japan [0.03%]
日本进口的细粒棘球绦虫G3基因型导致的囊型棘球蚴病病例
Maki Goto,Hidetoshi Nomoto,Noriko Iwamoto et al.
Maki Goto et al.
A Japanese man in his 50s who had lived in high-altitude rural areas, including the Tibet Autonomous Region, Qinghai Province and western Sichuan Province in China, Mongolia, and northern India, for more than 25 years presented with abdomin...