Long-term clinical outcome of lung radiofrequency ablation in patients with musculoskeletal sarcoma [0.03%]
肌肉骨骼肉瘤患者肺射频消融的长期临床疗效分析
Tomoki Nakamura,Masashi Fujimori,Takashi Yamanaka et al.
Tomoki Nakamura et al.
Background: Long-term outcomes in patients with lung metastases from sarcomas remain unreported. We retrospectively evaluated the clinical utility of lung radiofrequency ablation (RFA) in 52 patients with musculoskeletal ...
CD8/CD4 ratio, CD56, and PD-L1 as prognostic markers in sinonasal mucosal melanoma [0.03%]
鼻腔鼻窦黏膜黑色素瘤中CD8／CD4比值、CD56及PD-L1的预后价值研究
Chiau-Sheng Jang,I-Chieh Chuang
Chiau-Sheng Jang
Background: Sinonasal mucosal melanoma (SNMM) is an aggressive malignancy with limited prognostic markers. This study aimed to determine whether immune markers, including the CD8 to CD4 lymphocyte ratio, CD56-positive lym...
Identifying immune-related predictive factors for post-eribulin therapy in patients with HER2-negative advanced breast cancer- a multicenter retrospective study [0.03%]
识别HER2阴性晚期乳腺癌患者厄洛替尼治疗后免疫相关预测因素的多中心回顾性研究
Yuri Takamatsu,Yoshiya Horimoto,Yasuo Miyoshi et al.
Yuri Takamatsu et al.
Background: In the EMBRACE study, eribulin (ERI) monotherapy improved the overall survival (OS) of patients with HER2-negative advanced breast cancer (HER2-negative ABC). A post hoc analysis identified the baseline absolu...
Safety and oncologic outcomes of total laparoscopic versus abdominal hysterectomy following diagnostic conization for adenocarcinoma in situ and stage IA1 cervical cancer: a multicenter retrospective study [0.03%]
诊断性锥切后全腹腔镜与开腹子宫切除术治疗腺癌原位及IA1期宫颈癌的围手术期安全性及肿瘤学结局：一项多中心回顾性研究
Yoshitaka Kaido,Masahiro Kagabu,Yohei Chiba et al.
Yoshitaka Kaido et al.
Background: While simple hysterectomy is the standard treatment for adenocarcinoma in situ (AIS) and stage IA1 cervical cancer, minimally invasive surgery has been increasingly adopted. However, evidence on the safety and...
Long-term intelligence after high-dose radiotherapy to the primary site versus chemotherapy and whole-ventricle radiotherapy in patients with germinoma [0.03%]
高剂量局部放疗与化疗及全脑室照射治疗生殖细胞瘤患者的长期智力比较研究
Masayuki Kanamori,Yumi Sugawara,Yoshiteru Shimoda et al.
Masayuki Kanamori et al.
Background: Until 1995, patients with newly diagnosed germinoma received 40-60 Gy of radiation to the primary site with or without chemotherapy (regimen A). After 2000, treatment shifted to chemotherapy followed by 24 Gy ...
Comparison of nedaplatin and cisplatin in concurrent chemoradiotherapy for cervical cancer: a systematic review and meta-analysis [0.03%]
顺铂和耐折 platinum同期放化疗治疗宫颈癌的比较：系统评价和 Meta 分析
Maki Umemiya,Kazuhiro Kou,Yoshihide Inayama et al.
Maki Umemiya et al.
Background: Cisplatin-based concurrent chemoradiotherapy (CCRT) is the standard treatment for locally advanced cervical cancer; however, its nephrotoxicity and gastrointestinal toxicity often limit treatment eligibility a...
Intratumoral heterogeneity and chemotherapy-induced alteration of CLDN18.2 expression in resectable gastric cancer [0.03%]
可手术胃癌的瘤内异质性及化疗诱导的CLDN18.2表达改变
Shinnosuke Nagano,Yukinori Kurokawa,Takaomi Hagi et al.
Shinnosuke Nagano et al.
Background: Claudin-18 isoform-2 (CLDN18.2) is a novel biomarker and therapeutic target for gastric cancer (GC). It may exhibit the intratumoral heterogeneity and varying expressions between biopsy and surgically resected...
Prevalence of sarcopenia in esophageal cancer patients receiving preoperative neoadjuvant therapy: a systematic review and meta-analysis [0.03%]
新辅助治疗食管癌患者肌少症的患病率：系统评价和荟萃分析
Mohamed Abosheisha,Mohamed Abdellatif,Muhammed Kandeel et al.
Mohamed Abosheisha et al.
Background: Sarcopenia is a critical comorbidity in esophageal cancer patients undergoing neoadjuvant therapy (NAT), linked to poor surgical outcomes and survival. However, its reported prevalence varies widely, and a com...
Optimizing pelvic lymph node dissection in bladder cancer: obturator focus, pN1 prognosis, and sentinel node feasibility [0.03%]
膀胱癌盆腔淋巴结清扫术的优化： Obturator区域、pN1预后及前哨淋巴结分期可行性研究
Jun Miki,Shoji Kimura,Fumihiko Urabe et al.
Jun Miki et al.
Background: To determine the optimal extent of pelvic lymph node dissection in bladder cancer, evaluating the prognostic relevance of nodal sub-staging, and assessing the feasibility of sentinel lymph node biopsy and omis...
Circulating tumor DNA methylation and gut microbiota in colorectal cancer: diagnostic, prognostic, and therapeutic implications [0.03%]
循环肿瘤DNA甲基化和结直肠癌肠道微生物组的诊断、预后和治疗意义
Kazuhito Sasaki,Shigenobu Emoto,Yuichiro Yokoyama et al.
Kazuhito Sasaki et al.
Colorectal cancer remains one of the leading causes of cancer-related mortality worldwide, and early detection is essential for improving outcomes. Advances in liquid biopsy technologies and microbiota research have shed new light on diagno...