Barriers and facilitators for online genetic care for hereditary cancer in Japan: findings from surveys of both clients and medical professionals [0.03%]
日本遗传性癌症在线遗传护理的障碍与促进因素：来自客户和医务人员调查的结果
Sayaka Ueno,Yusaku Urakawa,Fumino Kato et al.
Sayaka Ueno et al.
Background: Online genetic care can offer a promising solution to the shortage of qualified medical professionals in genetic medicine, which leads to regional disparities in access. However, despite global adoption, its u...
Optimal adjuvant strategy in intermediate-risk cervical cancer: a systematic review and meta-analysis [0.03%]
中危宫颈癌辅助治疗的最优方案：系统性回顾和meta分析
Akira Yokoi,Hiroko Machida,Mika Okazawa-Sakai et al.
Akira Yokoi et al.
Objective: To evaluate the efficacy and safety of adjuvant treatment strategies following radical hysterectomy for intermediate-risk, early-stage cervical cancer using a reconstructed HR Hazard ratio (HR) meta-analysis. ...
Association between preoperative diaphragmatic dome height for overall survival in patients with lung cancer and obstructive ventilatory disorder [0.03%]
肺癌合并阻塞性通气功能障碍患者膈穹隆高度与总生存期的关系分析
Masaya Noguchi,Yuji Higashimoto,Toshiki Takemoto et al.
Masaya Noguchi et al.
Background: To investigate the relationship between preoperative diaphragmatic dome height (DDH), measured on chest radiographs, and postoperative overall survival (OS) and disease-specific survival (DSS) due to respirato...
Prevalence and prognostic impact of cancer cachexia in patients with bladder cancer: a multicenter retrospective study [0.03%]
膀胱癌患者恶病质的流行率及预后影响：一项多中心回顾性研究
Osamu Mito,Satoru Muto,Kosuke Kitamura et al.
Osamu Mito et al.
Background: Cancer cachexia is characterized by progressive skeletal muscle loss and systemic inflammation. Although sarcopenia is a known prognostic factor in bladder cancer, the prevalence and prognostic significance of...
Naoko Hosono
Naoko Hosono
Over the past decade, AML therapy has evolved from the uniform "7 + 3" regimen toward a personalized approach. This transition integrates molecular genetic profiles with clinical fitness, driven by the genomic elucidation of AML and the dev...
Efficacy of bepotastine compared with hydroxyzine in preventing rituximab-induced infusion-related reactions in non-hodgkin lymphoma patients: a phase II, double-blind, multicenter, and randomized trial [0.03%]
贝帕斯特与羟嗪预防利妥昔单抗所致输液反应的疗效比较：非霍奇金淋巴瘤患者的双盲多中心随机II期临床试验
Yumi Kitahiro,Hironobu Minami,Kazuhiro Yamamoto et al.
Yumi Kitahiro et al.
Background: This study evaluated the efficacy of hydroxyzine and bepotastine, first- and second-generation H1 receptor antagonists (H1RA), as pretreatments to prevent infusion-related reactions (IRRs) during the initial r...
Skin toxicity induced by chemotherapy or molecular targeted therapy combined with immune checkpoint inhibitors in Asian patients: A literature review by the Japanese Pharmacist-led Oncodermatology Study Team [0.03%]
化疗或分子靶向治疗联合免疫检查点抑制剂所致亚洲人群皮肤毒性的文献综述：日本药师主导的肿瘤皮肤病学研究团队发起的一次回顾性分析
Yohei Iimura,Junichi Higuchi,Akimitsu Maeda et al.
Yohei Iimura et al.
Background: Combination therapy with immune checkpoint inhibitors (ICIs) and cytotoxic or targeted anticancer agents has improved survival in multiple cancers but may exacerbate drug-related skin toxicities. These toxicit...
Cachexia index as a prognostic indicator in patients with metastatic renal cell carcinoma treated with nivolumab plus ipilimumab: multicenter analysis [0.03%]
营养状况指数可以作为nivolumab联合ipilimumab治疗转移性肾细胞癌患者的预后指标：多中心分析
Shimpei Yamashita,Ryusuke Deguchi,Shuzo Hamamoto et al.
Shimpei Yamashita et al.
Background: The association between cachexia index (CXI) and prognosis in patients with metastatic renal cell carcinoma (RCC) is unclear. We investigated the prognostic impact of pretreatment CXI in patients with metastat...
Effectiveness of electronic patient-reported outcomes in patients with cancer undergoing immunotherapy: a real-world retrospective study [0.03%]
一项真实世界回顾性研究：评估电子患者报告结局在癌症免疫治疗患者中的有效性
Hideyuki Katsura,Yukio Suga,Shinji Kimoto et al.
Hideyuki Katsura et al.
Background: Immune checkpoint inhibitors (ICIs) are essential in advanced cancer treatments; however, they can cause severe immune-related adverse events (irAEs). Herein, we aimed to investigate the effectiveness of elect...
Real-world outcomes of chimeric antigen receptor T-cell therapy with pembrolizumab as holding and/or bridging therapy in relapsed/refractory primary mediastinal large B-cell lymphoma [0.03%]
用于缓解/桥接治疗的嵌合抗原受体T细胞联合帕博利珠单抗在难治复发性原发纵隔大B细胞淋巴瘤中的真实世界疗效分析
Risa Nishiyama,Shinichi Makita,Anna Hiratsuka et al.
Risa Nishiyama et al.
Background: Clinical data on chimeric antigen receptor (CAR) T-cell therapy in Japanese patients with relapsed/refractory primary mediastinal large B-cell lymphoma (R/R PMBCL) are limited. This study evaluated the safety ...