Sustained antiemetic efficacy of fosnetupitant versus aprepitant in carboplatin-based chemotherapy: a retrospective observational study [0.03%]
一项基于卡铂化疗的患者接受福司曲普坦与艾日布林止吐疗效的回顾性研究：一项观察性研究
Hiroshi Inano,Yoshihito Morimoto,Atsushi Kawamura et al.
Hiroshi Inano et al.
Background: Carboplatin (CBDCA) is highly emetogenic when administered at an area under the curve (AUC) ≥ 4, requiring triple antiemetic therapy, including an NK1 receptor antagonist (NK1 RA). Fosnetupitant (F-NTP), a lo...
Is neoadjuvant therapy necessary for resectable pancreatic cancer? A review of randomized controlled trials to date: a narrative review [0.03%]
新辅助治疗在可切除胰腺导管腺癌中的作用：系统回顾及meta分析
Hidetoshi Eguchi
Hidetoshi Eguchi
Perioperative systemic therapy, administered either preoperatively (neoadjuvant therapy) or postoperatively (adjuvant therapy), has been considered a strategy to improve the long-term prognosis of pancreatic cancer. While adjuvant therapy f...
Clinical profiles and predictors of symptomatic skeletal events in patients with metastatic castration-resistant prostate cancer receiving denosumab [0.03%]
地诺单抗治疗转移性激素难治性前列腺癌患者的临床特征和影响骨骼相关事件的预测因素
Mana Nakata,Fumihiko Urabe,Yu Imai et al.
Mana Nakata et al.
Background: Denosumab, a bone-modifying agent, reduces the incidence of skeletal-related events (SREs), but its optimal use in real-world metastatic castration-resistant prostate cancer (mCRPC) settings remains unclear. ...
Prognostic outcomes of immediate complete lymph node dissection versus observation in patients with acral melanoma of the sole with sentinel node metastasis: a retrospective, multicenter study [0.03%]
一期手术切除与观察随访对足底肢端黑色素瘤患者sentinel淋巴结转移的预后影响：一项回顾性、多中心研究
Sadao Inoue,Shigeru Koizumi,Naoya Yamazaki et al.
Sadao Inoue et al.
Background: The clinical utility of immediate complete lymph node dissection (CLND) following positive sentinel node (SN) remains controversial in acral melanoma (AM), in Asian populations where AM is more prevalent. This...
Supporting parents with cancer: a profile of patients using childcare services in a cancer center [0.03%]
癌症中心使用儿童护理服务的患者的家长状况描述
Mayu Moriyasu,Makiko Ono,Natsue Uehiro et al.
Mayu Moriyasu et al.
Background: In Japan, approximately 1 million individuals are newly diagnosed with cancer each year, and 56,000 patients have children under 18 years old. Children of patients with cancer face many challenges, and many pa...
Comparison of first-line immuno-oncology combinations with molecular targeted therapy in patients with advanced renal cell carcinoma undergoing hemodialysis: a real-world multicenter retrospective study [0.03%]
透析状态肾细胞癌患者一线免疫联合治疗与靶向治疗的回顾性多中心真实世界研究比较
Kosuke Ueda,Hiroki Kurata,Yoji Murakami et al.
Kosuke Ueda et al.
Background: Patients with advanced renal cell carcinoma (RCC) undergoing hemodialysis are often excluded from clinical trials. We aimed to evaluate real-world outcomes of first-line molecular targeted therapy (MTT) and im...
The changes of CD47 and PD-L1 (SP142) before and after neoadjuvant therapy help predict prognosis of patients with stage IIIA-N2 non-small cell lung cancer [0.03%]
新辅助治疗前后CD47和PD-L1（SP142）的变化有助于三期N2期非小细胞肺癌患者预后的判断
Qichang Jiang,Yan Lv,Yang Liu et al.
Qichang Jiang et al.
Objective: Non-small cell lung cancer (NSCLC) represents over 80% of lung cancer cases. Neoadjuvant therapy (NAT) improves overall survival (OS) of NSCLC patients. We explored clinicopathological significance of pre- and ...
Prognostic impact of lymphadenectomy in patients with advanced ovarian clear cell carcinoma: an ancillary analysis of the JGOG3017-A4 study [0.03%]
卵巢透明细胞癌患者淋巴结清扫术的预后影响：JGOG3017-A4研究的辅助分析
Satoe Fujiwara,Muneaki Shimada,Yuri Ito et al.
Satoe Fujiwara et al.
Background: Systematic pelvic and aortic lymphadenectomy in stage IIB-IVB patients with epithelial ovarian cancer, undergoing complete abdominal macroscopic resection with normal lymph nodes, was revealed to have no progn...
Prognostic impact of genomically matched therapy for solid cancers using real-world data from a provincial hospital in Japan [0.03%]
基于日本省级医院真实世界数据的实体肿瘤基因匹配治疗预后效果研究
Yoshinaga Okugawa,Takumi Fujiwara,Takahito Kitajima et al.
Yoshinaga Okugawa et al.
Background: Comprehensive genomic profiling (CGP) has been publicly reimbursed in Japan for 5 years, yet its impact on survival in real-world provincial settings remains unclear. ...
Real-world multicenter study of immune checkpoint inhibitors in advanced cervical cancer across HPV-associated and HPV-independent subtypes [0.03%]
基于HPV相关和非HPV依赖型晚期宫颈癌的免疫检查点抑制剂真实世界多中心研究
Kazuhiro Ko,Mayu Fukuda,Koji Yamanoi et al.
Kazuhiro Ko et al.
Background: Cervical cancer remains a major health problem, and HPV-independent subtypes such as gastric-type adenocarcinoma carry dismal outcomes. Although immune checkpoint inhibitors (ICIs) have improved survival in la...