Chronological transition in outcome of second-line treatment in patients with metastatic urothelial cancer after pembrolizumab approval: a multicenter retrospective analysis [0.03%]
帕博利珠单抗获批后转移性尿路上皮癌二线治疗结果的时间转换的多中心回顾分析
Teruki Isobe,Taku Naiki,Yosuke Sugiyama et al.
Teruki Isobe et al.
Background: After first-line chemotherapy failure, metastatic urothelial carcinoma (mUC) patients undergo pembrolizumab (PEM) or gemcitabine and docetaxel (GD) therapy. We retrospectively investigated outcomes of second-l...
Presence of serum RalA and serum p53 autoantibodies in 1833 patients with various types of cancers [0.03%]
1833例各种癌症患者血清RalA及p53自身抗体的存在
Tatsuki Nanami,Isamu Hoshino,Fumiaki Shiratori et al.
Tatsuki Nanami et al.
Background: RalA is a member of the Ras superfamily of small GTPases. The Anti-RalA autoantibodies (s-RalA-Abs) act as tumor markers in various types of cancer and are negatively associated with the p53 autoantibodies (s-...
An analysis of tumor-related skin temperature differences in malignant soft-tissue tumors [0.03%]
恶性软组织肿瘤相关的皮肤温度差异分析
Akiyoshi Shimatani,Manabu Hoshi,Naoto Oebisu et al.
Akiyoshi Shimatani et al.
Background: Soft tissue tumors are often accompanied with elevated skin temperature; however, studies concerning the relationship between soft-tissue tumors and skin temperature elevation are scarce. We aimed to evaluate ...
Clinical impact of primary tumour 123ImIBG response to induction chemotherapy in children with high-risk neuroblastoma [0.03%]
原发肿瘤对诱导化疗的123IMIBG反应对高风险神经母细胞瘤儿童临床结果的影响
Elwira Szychot,Daniel Morgenstern,Mark Chopra et al.
Elwira Szychot et al.
Background: More than 50% children with high-risk neuroblastoma (HR-NBL) experience disease progression, which we hypothesise is due to non-response of primary tumour to treatment. Current imaging techniques are unable to...
Meta-analysis of risk factors associated with oxaliplatin hypersensitivity reactions in cancer patients [0.03%]
癌症患者奥沙利铂超敏反应的危险因素的meta分析研究
Linhui Zhu,Huan Li,Qiong Du et al.
Linhui Zhu et al.
This study aimed to investigate risk factors associated with oxaliplatin hypersensitivity reactions in cancer patients through a meta-analysis. A comprehensive retrieve of Chinese databases China National Knowledge Infrastructure, Wanfang D...
Large and diffuse ductal carcinoma in situ: potentially lethal subtypes of "preinvasive" disease [0.03%]
大范围弥散型导管原位癌：“前侵犯”疾病的潜在致命亚型
Thomas J O&#x;Keefe,Olivier Harismendy,Anne M Wallace
Thomas J O&#x;Keefe
Purpose: Trials for DCIS have not explored whether outcomes for patients with large disease burden requiring mastectomy are comparable to those of patients with lumpectomy-amenable disease. We aim to identify whether pati...
Heterogeneous distribution of PD-L1 expression in the IASLC/ATS/ERS classification of lung adenocarcinoma [0.03%]
PD-L1表达在IASLC / ATS / ERS分类的肺腺癌中的异质性分布
Dachuan Zhang,Xie Gao,Zhantao Yan et al.
Dachuan Zhang et al.
Background: PD-L1 expression in tumor cells can predict the efficacy of PD-1/PD-L1 inhibitors and prognosis in patients. However, the correlation between the PD-L1 expression and the novel lung adenocarcinoma classificati...
Sarcopenia is associated with survival in patients with urothelial carcinoma treated with systemic chemotherapy [0.03%]
萨科朋症与尿路上皮癌患者接受全身化疗后的生存率有关
Ryutaro Shimizu,Masashi Honda,Shogo Teraoka et al.
Ryutaro Shimizu et al.
Background: Sarcopenia impacts perioperative outcomes and prognosis in various carcinomas. We aimed to investigate whether sarcopenia at the time of chemotherapy induction in patients with urothelial carcinoma is associat...
A phase 2, open-label, multicenter study of ixazomib plus lenalidomide and dexamethasone in adult Japanese patients with relapsed and/or refractory multiple myeloma [0.03%]
伊沙佐米联合来那度胺和地塞米松在日本多发性骨髓瘤成人患者中的2期、开放标签、多中心研究
Shinsuke Iida,Tohru Izumi,Takuya Komeno et al.
Shinsuke Iida et al.
Background: TOURMALINE-MM1 was a global study that demonstrated a significant improvement in progression-free survival with ixazomib plus lenalidomide and dexamethasone compared with placebo plus lenalidomide and dexameth...
Deferred radical prostatectomy in patients who initially elected for active surveillance: a multi-institutional, prospective, observational cohort of the PRIAS-JAPAN study [0.03%]
最初选择主动监测患者的deferred根治性前列腺切除术：PRIAS-JAPAN研究的多机构，前瞻，观察队列研究
Yoichiro Tohi,Takuma Kato,Masaki Nakamura et al.
Yoichiro Tohi et al.
Background: This study aimed to evaluate the pathological findings and oncological outcomes of deferred radical prostatectomy in patients who initially elected for active surveillance in a Japanese cohort. ...
Observational Study
International journal of clinical oncology. 2022 Jan;27(1):194-201. DOI:10.1007/s10147-021-02041-4 2022