Assessment for potential bias in multiplexed IL-10 and TNF-α from plex count [0.03%]
PLEX计数法检测IL-10和TNF-α的潜在偏倚评估
Wade M Sanders,Carrie A Karvonen-Gutierrez,Daniel S McConnell
Wade M Sanders
Objectives: Multiplex arrays offer a high-throughput, cost-effective means for quantifying multiple analytes simultaneously, essential for large-scale biomarker research. However, the shared reactive environment in multip...
Automation in value-based laboratory medicine: driving precision, capacity, and better outcomes [0.03%]
基于价值的实验室医学自动化：推动精准医疗、提高容量和改善预后
Damien Gruson,Tomáš Zima,Mario Plebani
Damien Gruson
Laboratory medicine lies at the core of modern healthcare, enabling timely diagnosis, effective patient monitoring, and increasingly personalized therapeutic strategies. Over the past decades, automation has profoundly reshaped the role of ...
One copy in one-pot for rapid and accurate SFTSV testing by LAC12b-2M [0.03%]
一步一管快速准确的SFTSV检测方法LAC12b-2M COPY
Ya Pang,Yongwei Duan,Yuehua Sun et al.
Ya Pang et al.
Objectives: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne pathogen that can cause a fatality rate as high as 12-50 %, posing a significant threat to public health. SFTSV is prevalent in mountai...
Holiday-associated biochemical patterns of pancreatitis: a 16-year retrospective analysis of ambulatory laboratory data (2009-2024) [0.03%]
基于2009年至2024年门诊实验室数据的胰腺炎假日相关生化模式的16年回顾性分析
Marlene Hollenstein,Van Lin Nguyen,Thomas Szekeres et al.
Marlene Hollenstein et al.
Comparability, compatibility, equivalence and interchangeability: metrological concepts widely misunderstood in laboratory medicine [0.03%]
计量学概念在临床实验室医学中常被误解：可比性、相容性、等效性和互换性
Raúl Rigo-Bonnin,Sofía Durán-Espín,Míriam Valbuena-Asensio et al.
Raúl Rigo-Bonnin et al.
Background: Method-comparison studies in laboratory medicine are routinely interpreted using regression-based or Bland-Altman analyses. Although useful descriptively, these statistical procedures are frequently misapplied...
Multi-analytical identification of the synthetic opioids cychlorphine and methiodone (IC-26) in drug seizures: first detection in Europe [0.03%]
多种分析方法结合鉴定毒品缴获中的人工合成阿片类物质赛氯啡和美依托酮（IC-26）：欧洲首次发现
Paméla Dugues,Tiphaine Robin,Marie Bellouard et al.
Paméla Dugues et al.
Objectives: The rapid emergence of highly potent synthetic opioids represents a growing challenge for forensic and clinical laboratories. Methods: ...
Establishment of allowable total error for semen analysis based on the state of the art in China [0.03%]
基于中国精液分析现状的允许总误差建立
Yan Zheng,Lin Yu,Yingbi Wu et al.
Yan Zheng et al.
Objectives: To establish evidence-based analytical performance specifications (APS), specifically allowable total error (TEa), for five fundamental semen analysis parameters (sperm concentration, progressive motility, tot...
Contribution of SuPAR for patients in a situation of uncertainty downstream of emergencies [0.03%]
SuPAR检测在不确定急诊结局患者的临床预后价值
Marina Brailova,Dorian Teissandier,Bruno Pereira et al.
Marina Brailova et al.
Objectives: Evolution is difficult to predict for some patients at emergency department (ED). The soluble urokinase plasminogen activator receptor (suPAR) is a non-specific prognostic inflammatory blood biomarker with a h...
Secondary use of external quality assessment data - estimating inter-assay variation in LOINC-coded datasets [0.03%]
外部质量评估数据的二次利用——在LOINC编码的数据集中估算检测间变异性的方法
Michael Vogeser,Katharina Habler
Michael Vogeser
The secondary scientific use of routine laboratory data will increasingly rely on LOINC as a semantic standard, particularly within the European Health Data Space (EHDS). LOINC enables the aggregation of large data sets from clinical care f...
Comparison of blood sample quality and test results between robotic and manual venipuncture: a pilot study [0.03%]
机器人采血与手动刺针的血液样本质量及检测结果比较：一项试点研究
Rong Wang,Jiazheng Wang,Wenhan Wu et al.
Rong Wang et al.
Objectives: This study aimed to evaluate the feasibility of robotic venipuncture in clinical settings and compare its performance with manual venipuncture in terms of blood specimen quality and test results. ...