CYFRA 21-1 in lymph node fine-needle aspiration washouts: added value in differentiated thyroid cancer [0.03%]
细针抽吸冲洗液中的细胞角蛋白碎片21-1片段在分化型甲状腺癌中的临床意义
Alfredo Campenni,Lilla Bonanno,Petra Petranović Ovčariček et al.
Alfredo Campenni et al.
Objectives: Cervical lymph node metastases represent a key challenge in patients with differentiated thyroid carcinoma (DTC). Fine-needle aspiration cytology (FNAC) and thyroglobulin (Tg) measurement in fine-needle washou...
Towards the future of Endocrine Laboratory Medicine: defining the role of laboratory medicine specialists to strengthen the clinical-biological partnership - a joint opinion paper of EFLM-C:YS, IFCC TF-YS, and ESE-EYES [0.03%]
迈向内分泌实验室医学的未来：定义实验室医学专家的角色以加强临床生物伙伴关系——EFLM-C：YS，IFCC TF-YS和ESE-EYES联合意见书
Charles R Lefèvre,Patricia Vaduva,Aleš Kvasnička et al.
Charles R Lefèvre et al.
Clinical endocrinology relies critically on high-quality biochemical data for diagnosis, therapeutic decisions, and long-term patient monitoring. As endocrine diagnostics grow more complex due to expanding test menus, technological advances...
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of 17-hydroxyprogesterone in human serum and plasma [0.03%]
基于同位素稀释液相色谱串联质谱法的17羟基孕酮候选参考测量程序及其在人血清和血浆中定量的应用
Martina Bachmann,Myriam Ott,Neeraj Singh et al.
Martina Bachmann et al.
Objectives: Accurate measurement of 17α-hydroxyprogesterone (17-OHP) in human serum and plasma is required for steroid profiling, to ensure the appropriate diagnosis of congenital adrenal hyperplasia. Therefore, an isoto...
An isotope dilution-liquid chromatography-tandem mass spectrometry-based candidate reference measurement procedure for the quantification of linezolid in human serum and plasma [0.03%]
基于同位素稀释液相色谱-串联质谱法定量人类血清和血浆利奈唑胺候选参考测量程序的研究
Marie Kubicova,Neeraj Singh,Carina Schuster et al.
Marie Kubicova et al.
Objectives: The quantification of linezolid in serum and plasma matrices is crucial for therapeutic drug monitoring and pharmacokinetic studies. A reference measurement procedure (RMP) was developed and validated to provi...
Considerations and pragmatic strategies for implementation of point of care testing for high sensitivity cardiac troponin into the acute care setting [0.03%]
高敏感性心肌肌钙蛋白床旁检测在急诊科实施的考量及实用策略
Paul Collinson,Leo Lam,John W Pickering et al.
Paul Collinson et al.
A challenge in the implementation of rapid risk-stratification algorithms for patients with suspected acute coronary syndrome is the turnaround time for cardiac troponin (cTn) from blood sampling to reporting of results. Measurement of cTn ...
Rare ANA patterns and their clinical correlates: a retrospective large-cohort study [0.03%]
罕见ANA模式及其临床相关性：回顾性大规模队列研究
Renren Ouyang,Xuebing Zhang,Lian Wang et al.
Renren Ouyang et al.
Objectives: To determine the prevalence and clinical associations of rare HEp 2 indirect immunofluorescence ANA patterns and to evaluate their relationships with disease categories, ANA titers, and expression form. ...
Laboratory quality indicators: persistent variability despite international harmonization efforts [0.03%]
国际标准化工作之下仍存实验室质量指标差异性问题分析
Diogo Jerônimo,Luiza Bottino Balli,José Antonio Tesser Poloni et al.
Diogo Jerônimo et al.
Discrepancies of results for post infusion levels of extended half-life factor VIII/IX concentrates - a cause of concern, awaiting for solution [0.03%]
长效八因子/九因子浓缩制剂输注后药物浓度检测结果差异性问题值得重视并亟待解决
Armando Tripodi,Cristina Novembrino,Flora Peyvandi
Armando Tripodi
Hemophilia A and B are X-linked hemorrhagic disorders, characterized by low/dysfunctional factor (F)VIII or FIX, respectively. The history of hemophilia treatment has evolved remarkably over time from the introduction of cryoprecipitate in ...
Personalized reference intervals based on biological variation: a critical evaluation of strengths and limitations [0.03%]
基于生物变异性个人参考区间的批判性评价：优势与局限性
Abdurrahman Coskun,Mario Plebani
Abdurrahman Coskun