Recent advances in glycosome biogenesis and its implications for drug discovery [0.03%]
糖体生物发生研究的最新进展及其对于新药研发的意义
Lisa Hohnen,Chethan K Krishna,Lewis Walker et al.
Lisa Hohnen et al.
The phylum Euglenozoa, within the Eukaryote domain, includes diverse protists such as the medically significant kinetoplastids, characterized by their unique kinetoplast DNA. Both kinetoplastids and their sister class Diplonemea possess gly...
Highlight: organelles on and off the map: diversity, specialization and subdomains [0.03%]
亮点：细胞器在图谱上和之外：多样性、特化性和亚域
Yury S Bykov,Emma J Fenech,Blanche Schwappach
Yury S Bykov
Editorial
Biological chemistry. 2025 Dec 1. DOI:10.1515/hsz-2025-0237 2025
Felix Hoppe-Seyler (1825-1895): a pioneer in the field of biochemistry with many significant contributions to the development of the discipline [0.03%]
菲利克斯·霍普-塞勒（1825-1895）：在生物化学领域开拓和做出诸多贡献的先驱者
Bernhard Brüne
Bernhard Brüne
Editorial
Biological chemistry. 2025 Nov 25. DOI:10.1515/hsz-2025-0232 2025
Molecular mechanisms shaping the actin filament scaffold of dendritic filopodia [0.03%]
调控树突丝状伪足肌动蛋白纤维骨架的分子机制
Marco B Rust,Sharof Khudayberdiev
Marco B Rust
Dendritic spines are the postsynaptic compartment of most excitatory synapses in the vertebrate brain. Their morphology is defined by a complex actin scaffold consisting of branched and unbranched actin filaments (F-actin), which constitute...
Tim P Levine
Tim P Levine
The small protein family of VAMP-associated proteins (VAPs) have the unique position in cell biology as intracellular signposts for the Endoplasmic Reticulum (ER). VAP is recognised by a wide range of other proteins that use it to target th...
Formulation of pH-responsive nanoplexes based on an antimicrobial peptide and sodium alginate for targeted delivery of vancomycin against resistant bacteria [0.03%]
一种基于抗微生物肽和海藻酸钠的pH响应纳米多聚体的制备，用于万古霉素的靶向递送以对抗耐药菌
Shourok Shahin,Calvin A Omolo,Eman Elhassan et al.
Shourok Shahin et al.
The rapid spread of bacterial resistance to antibiotics necessitates the development of innovative strategies to enhance their efficacy. One promising approach is incorporating antimicrobial peptides (AMPs) to synergize antibiotics. Herein,...
New polyamine oxidases from Ogataea parapolymorpha DL-1: expanding view on non-conventional yeast polyamine catabolism [0.03%]
来自Ogataea parapolymorpha DL-1的新型聚胺氧化酶：非传统酵母聚胺分解代谢的新见解
Diana I Golovina,Egor P Sergeev,Ivan I Lentin et al.
Diana I Golovina et al.
Polyamines are ubiquitous and essential for cellular physiology, yet their metabolic pathways and functions remain only partially understood. Polyamine oxidases (PAO) are key to elucidating their physiological roles. In the methylotrophic y...
The 76th Mosbacher Colloquium: AI-driven (r)evolution in structural biology and protein design [0.03%]
第76届莫斯巴赫研讨会：结构生物学与蛋白质设计的AI驱动型（革命）变迁
Birte Höcker,Ina Koch,Janosch Hennig
Birte Höcker
The 76th Mosbacher Kolloquium focused on recent advances in machine learning applications for structural biology and protein design. It covered topics spanning artificial intelligence-driven protein structure prediction, integrative modelin...
Drishan Dahal,Luis D Cruz-Zargoza,Peter Rehling
Drishan Dahal
Mitochondria are essential for cellular metabolism, serving as the primary source of adenosine triphosphate (ATP). This energy is generated by the oxidative phosphorylation (OXPHOS) system located in the inner mitochondrial membrane. Impair...
Biogenesis and function of the mitochondrial solute carrier (SLC25) family in yeast [0.03%]
酵母线粒体溶质载体(SLC25)家族的生物发生和功能
Celina Nauerz,Ophry Pines,Johannes M Herrmann
Celina Nauerz
The mitochondrial solute carrier family, also called SLC25 family, comprises a group of structurally and evolutionary related transporters that are embedded in the mitochondrial inner membrane. About 35 and 53 mitochondrial carrier proteins...