[Pharmacy reloaded-Comprehensive competence in all aspects of pharmaceuticals] [0.03%]
[ Pharmacy reloaded——药物所有方面的综合能力]
Ulrich Jaehde,Peter Heisig
Ulrich Jaehde
[Infections with the human pathogenic Mycoplasma species M. genitalium and M. pneumoniae : Current epidemiological aspects] [0.03%]
[由人病原性支原体种属M. genitalium和M. pneumoniae引起的感染:当前的流行病学方面]
Roger Dumke
Roger Dumke
Two human pathogenic mycoplasma species, Mycoplasma pneumoniae and M. genitalium currently pose challenges for the clinical practice.M. pneumoniae is a common cause of community-acquired respiratory infections, which can lead to asymptomati...
[Phage therapeutics and pharmaceutical legislation: classification, manufacture, placing on the market, and application] [0.03%]
噬菌体疗法和药政法规:分类、生产、投放市场及应用
Timo Faltus
Timo Faltus
Currently, most phage therapeutics are individualized, that is, prepared specifically for a single patient. In this case, the preparation is usually decentralized and takes place in the respective hospital pharmacies as extemporaneous prepa...
[Medical ethical challenges of phage therapy-informed consent, study design and therapeutic trial] [0.03%]
噬菌体治疗的医学伦理挑战——知情同意、研究设计和临床试验
Hans Zillmann
Hans Zillmann
The antibiotics crisis is increasing interest in bacteriophages and related therapeutic approaches. The translation of phage therapy into clinical application faces various ethical challenges. These include the patient's informed consent ba...
[Strategies for mitigating antibiotic resistance in human medicine from the perspective of the Ministry of Health] [0.03%]
卫生部对人类医学中抗生素抗药性缓解策略的观点
Alexandra Clarici
Alexandra Clarici
Antibiotic resistance (AMR) is increasing worldwide. The complex interrelationships in their development and spread require a bundle of measures and a cross-sectoral approach that considers the One Health approach. The German Antibiotic Res...
[Regulation of phage therapy medicinal products: developments, challenges and opportunities] [0.03%]
[关于噬菌体治疗药物的管理:进展、挑战及机遇]
Miriam Fürst-Wilmes,Vanessa Respondek,Nils Lilienthal et al.
Miriam Fürst-Wilmes et al.
Due to their biological properties, bacteriophages represent a regulatory peculiarity and a challenge for drug approval. Adopted European guidelines on pharmaceutical quality, preclinical, and clinical development are only partially applica...
Christine Rohde
Christine Rohde
Phages (bacteriophages) are viruses that specifically infect and kill bacteria. They are very abundant in nature, playing a highly relevant role in microbial ecosystems. In medicine, they are investigated as a potential alternative or suppl...
[Potential of bacteriophage therapy in Germany: evidence and clinical relevance] [0.03%]
[德国噬菌体治疗的潜力:证据和临床意义]
Felix Bröcker,Christian Willy
Felix Bröcker
Bacteriophage therapy (phage therapy) holds great potential in addressing the growing threat of infections caused by multidrug-resistant bacteria. Registry studies and systematic reviews indicate that phage treatments are effective in appro...
[Development of cannabis use from adolescence to young adulthood and risk and protective factors for problematic use-results of a longitudinal study] [0.03%]
从青少年到成年早期的大麻使用发展及问题性使用的危险与保护因素——一项纵向研究的结果
Ann-Katrin Job,Lina-Theresa Brieske
Ann-Katrin Job
Introduction: On April 1, 2024, the new cannabis law came into force, legalizing the use of cannabis in Germany. Even before, Cannabis had been one of the most commonly used drugs. However, problematic cannabis use is rel...