[Science and practice in public health services: experiences from Saxony-Anhalt and perspectives for sustainable public health services] [0.03%]
Doreen Wolff,Christian Apfelbacher,Robert Pohl et al.
Doreen Wolff et al.
Against the backdrop of the Pact for the Public Health Service (Pakt für den Öffentlichen Gesundheitsdienst; Pakt ÖGD), the commitment to evidence-informed practice is increasingly shaping the strategic development of Germany's Public He...
[Exposure inquiries related to preparations containing plant-based ingredients in Germany: analysis of inquiries (2013-2022) at the Joint Poison Information Center in Erfurt] [0.03%]
Sebastian Wendt,Daniel Linden,Dagmar Prasa et al.
Sebastian Wendt et al.
Background: Preparations containing plant-derived components, such as those found in herbal medicinal products, medical devices, dietary supplements, and cosmetics, are readily accessible and may lead to adverse effects o...
[State-sponsored doping in GDR elite sport: health consequences, reappraisal, and questions of legal compensation] [0.03%]
Carsten Spitzer,Burkhard Bley
Carsten Spitzer
Against the backdrop of the ideological rivalry between communism and capitalism, sport in the GDR was exploited for political ends. This was evident, among other things, in a state-directed, controlled, hierarchically organized and, in par...
[Development of the epidemiology of antibiotic-resistant pathogens in human medicine and their significance for the health system in Germany] [0.03%]
Tim Eckmanns,Felix Reichert,Marc Schneider et al.
Tim Eckmanns et al.
The World Health Organization (WHO) has ranked antibiotic resistance as one of the 10 biggest global threats, leading to significant morbidity, mortality, and economic burden. In Germany the developing resistance situation is critical. The ...
[Development and spread of antibiotic resistance in the environment due to increased anthropogenic input of antibiotic residues and resistant pathogens] [0.03%]
[由于抗生素残留和耐药病原体的人为输入增加导致环境中的抗生素抗药性的发展和传播]
Merit Maren Prüß,Sebastian Guenther
Merit Maren Prüß
The use of antibiotics for antimicrobial therapy revolutionized medical practice. However, the frequent and sometimes inappropriate use of these drugs in both human and veterinary medicine has had significant consequences. This article prov...
[Pharmacokinetic and metabolic considerations of antibiotic usage in children and the elderly] [0.03%]
[儿科和老年人抗菌药物应用的药代动力学及代谢特点考虑]
Nils-Olaf Hübner
Nils-Olaf Hübner
The efficacy of antimicrobial therapies depends on achieving a pharmacokinetic/pharmacodynamic target. Therefore, correct dosing is crucial for the efficacy and safety of antimicrobial therapies. This article provides an overview of the pha...
[Antibiotics and phages: effects of combined therapy on susceptibility and resistance of bacterial pathogens] [0.03%]
抗生素和噬菌体：联合治疗对细菌病原体易感性和抗性的影响
Peter Heisig,Anke Heisig
Peter Heisig
The increasing use of antibiotics both in human therapy and for non-therapeutic applications with simultaneous reduction in antibiotic drug development have led to a world-wide rise in antibiotic resistance. Before the age of antibiotics, b...
[Molecular mechanisms underlying the development and spread of antibiotic resistance] [0.03%]
抗生素耐药性的发展和传播机制研究进展
Anke Heisig,Peter Heisig
Anke Heisig
Antibiotics are characterized by their selective toxicity against bacterial pathogens. Due to the high genetic flexibility of bacteria, which includes mutations in their own genes as well as the uptake of foreign genes from other species, p...
[Modulation of the gut microbiome for the eradication of multidrug-resistant pathogens: current approaches and perspectives] [0.03%]
[调节肠道微生物组以根除多重耐药病原体：当前方法和展望]
Tobias Weirauch,Maria J G T Vehreschild
Tobias Weirauch
The global rise in antibiotic resistance represents one of the greatest threats facing modern medicine. Colonization of the gastrointestinal tract with multidrug-resistant organisms is considered a critical risk factor for nosocomial infect...
Alexander Klimka,Liza Marie Maus
Alexander Klimka
Vaccinations against bacterial pathogens play a crucial role in infection prevention, especially given the growing prevalence of antibiotic resistance. Historically, vaccines against cholera, diphtheria, and pertussis (whooping cough) marke...