Phase 1 study of sulfasalazine and cisplatin for patients with CD44v-positive gastric cancer refractory to cisplatin (EPOC1407) [0.03%]
硫唑嘌呤联合顺铂治疗CD44v阳性耐药胃癌的I期临床研究(EPOC1407)
Kohei Shitara,Toshihiko Doi,Osamu Nagano et al.
Kohei Shitara et al.
A previous dose-escalation study of sulfasalazine (SSZ), an inhibitor of cystine-glutamate exchange transporter xc (-), in the variant form of CD44 (CD44v)-positive cancer stem cells (CSCs) suggested that administration of SSZ induces the r...
Five-year survival analysis of surgically resected gastric cancer cases in Japan: a retrospective analysis of more than 100,000 patients from the nationwide registry of the Japanese Gastric Cancer Association (2001-2007) [0.03%]
日本全国胃癌协会胃癌注册登记的胃癌手术切除标本5年存活率回顾性分析(2001年至2007年,超过10万例)
Hitoshi Katai,Takashi Ishikawa,Kohei Akazawa et al.
Hitoshi Katai et al.
Background: The aim of this retrospective study was to investigate the tumor characteristics, surgical details, and survival distribution of surgically resected cases of gastric cancer from the nationwide registry of the ...
Polymorphisms in CARS are associated with gastric cancer risk: a two-stage case-control study in the Chinese population [0.03%]
CARS基因多态性与胃癌发生相关的病例对照研究
Tian Tian,Ling Xiao,Jiangbo Du et al.
Tian Tian et al.
Background: The cysteinyl transfer RNA synthetase gene (CARS) is located on chromosome band 11p15.5, which is an important tumor-suppressor gene region. Mutations in CARS have been identified in many kinds of cancers; how...
Long-term outcome of endoscopic submucosal dissection is comparable to that of surgery for early gastric cancer: a propensity-matched analysis [0.03%]
内镜下黏膜下层剥离术与手术治疗早期胃癌的长期疗效相当:倾向匹配分析
Hye Kyung Jeon,Gwang Ha Kim,Bong Eun Lee et al.
Hye Kyung Jeon et al.
Background: Data concerning the long-term outcomes of endoscopic submucosal dissection (ESD) versus surgery for early gastric cancer (EGC) are limited. We aimed to compare the long-term outcomes of ESD and surgery for pat...
Anthracycline-based triplets do not improve the efficacy of platinum-fluoropyrimidine doublets in first-line treatment of advanced gastric cancer: real-world data from the AGAMEMON National Cancer Registry [0.03%]
基于蒽环类药物的三联疗法不能改善铂-氟尿嘧啶双药方案作为一线治疗晚期胃癌的有效性:来自AGAMEMON国家癌症登记处的真实世界数据
A Carmona-Bayonas,P Jiménez-Fonseca,A Custodio et al.
A Carmona-Bayonas et al.
Background: Although anthracycline-based triplets are one of the most widely used schedules to treat advanced gastric cancer (AGC), the benefit of including epirubicin in these therapeutic combinations remains unknown. Th...
Expression and function of Uc.160+, a transcribed ultraconserved region, in gastric cancer [0.03%]
胃癌中转录的超保守区域Uc.160+的表达及功能研究
Ririno Honma,Keisuke Goto,Naoya Sakamoto et al.
Ririno Honma et al.
Background: Transcribed ultraconserved regions (T-UCRs) are a novel class of noncoding RNAs that are highly conserved among the orthologous regions in most vertebrates. It has been reported that T-UCRs have distinct signa...
About HER2 monitoring using liquid biopsies in patients with gastric cancer [0.03%]
关于利用液体活检监测胃癌患者HER2状态
Arnaud Uguen
Arnaud Uguen
Long-term follow-up study of gastric adenoma; tumor-associated macrophages are associated to carcinoma development in gastric adenoma [0.03%]
长期跟踪研究胃腺瘤;肿瘤相关巨噬细胞与胃腺瘤癌变有关
Daiki Taniyama,Kiyomi Taniyama,Kazuya Kuraoka et al.
Daiki Taniyama et al.
Background: Some gastric adenomas may progress to adenocarcinoma in a short time, but others remain as adenoma for a long time. Methods: ...
Phase I/II study of a combination of capecitabine, cisplatin, and intraperitoneal docetaxel (XP ID) in advanced gastric cancer patients with peritoneal metastasis [0.03%]
用于治疗腹膜转移性晚期胃癌患者的卡培他滨、顺铂和腹腔注射多西紫杉醇(XP ID)联合方案I/II期临床研究
Hyungwoo Cho,Min-Hee Ryu,Kyu-Pyo Kim et al.
Hyungwoo Cho et al.
Background: This study was conducted to determine the recommended dose (RD) of intraperitoneal docetaxel (ID) in combination with systemic capecitabine and cisplatin (XP) and to evaluate its efficacy and safety at the RD ...
Knockdown of KRT17 by siRNA induces antitumoral effects on gastric cancer cells [0.03%]
siRNA敲低KRT17诱导胃癌细胞的抗肿瘤效应
Mihaela Chivu-Economescu,Denisa L Dragu,Laura G Necula et al.
Mihaela Chivu-Economescu et al.
Background: Keratin 17 (KRT17) was shown to be an important molecular marker for predicting the carcinogenesis, progression, and prognosis of various cancer types. Our previous studies identified KRT17 as a possible bioma...