Molecular profiling and comprehensive genome-wide analysis of somatic copy number alterations in gastric intramucosal neoplasias based on microsatellite status [0.03%]
基于微卫星状态的胃黏膜下肿瘤分子分型及全基因组拷贝数改变综合分析
Tamotsu Sugai,Makoto Eizuka,Noriyuki Arakawa et al.
Tamotsu Sugai et al.
Background: We attempted to identify the molecular profiles of gastric intramucosal neoplasia (IMN; low-grade dysplasia, LGD; high-grade dysplasia, HGD; intramucosal cancer, IMC) by assessing somatic copy number alteratio...
The significance of OLGA and OLGIM staging systems in the risk assessment of gastric cancer: a systematic review and meta-analysis [0.03%]
OLGA和OLGIM分期系统在胃癌风险评估中的意义：系统性回顾及meta分析
Hu Yue,Liu Shan,Lv Bin
Hu Yue
Background: Despite extensive research on the criteria for the assessment of gastric cancer risk using the Operative Link on Gastritis Assessment (OLGA) and Operative Link on Gastritis/Intestinal-Metaplasia Assessment (OL...
The efficacy and safety of targeted therapy with or without chemotherapy in advanced gastric cancer treatment: a network meta-analysis of well-designed randomized controlled trials [0.03%]
精准治疗联合化疗与单纯化疗在晚期胃癌治疗中的有效性和安全性：良好设计的随机对照试验的网络meta分析
Ting-Ting Zhao,Hao Xu,Hui-Mian Xu et al.
Ting-Ting Zhao et al.
Background: Advanced gastric cancer (AGC) is a severe malignant tumor associated with high mortality. Targeted therapy is an important approach for improving the therapeutic effects of AGC treatment. This study evaluates ...
Family history of cancer in first-degree relatives and risk of gastric cancer and its precursors in a Western population [0.03%]
一级亲属癌症家族史与西方人群胃癌及其前驱病变风险的关系
Minkyo Song,M Constanza Camargo,Stephanie J Weinstein et al.
Minkyo Song et al.
Background: Family history may inform risks of gastric cancer and preneoplastic lesions. Methods: We examined associations with history...
Two-point measurement of amylase in drainage fluid predicts severe postoperative pancreatic fistula after gastric cancer surgery [0.03%]
腹腔引流液淀粉酶两点测量预测胃癌术后严重胰瘘发生
Satoshi Kamiya,Naoki Hiki,Koshi Kumagai et al.
Satoshi Kamiya et al.
Background: Early identification of patients at risk of postoperative pancreatic fistula (POPF) allows appropriate management after gastrectomy. Although some reports have suggested a correlation between POPF and the conc...
Novel epigenetic markers for gastric cancer risk stratification in individuals after Helicobacter pylori eradication [0.03%]
根除幽门螺杆菌后个体胃癌风险分层的新表观遗传标志物
Masahiro Maeda,Satoshi Yamashita,Taichi Shimazu et al.
Masahiro Maeda et al.
Background: The risk stratification of healthy individuals after Helicobacter pylori eradication is an urgent issue. The assessment of aberrant DNA methylation accumulated in gastric tissues with normal appearance, which ...
Introducing laparoscopic total gastrectomy for gastric cancer in general practice: a retrospective cohort study based on a nationwide registry database in Japan [0.03%]
基于日本全国登记数据库的回顾性队列研究介绍胃癌普外科腹腔镜全胃切除术
Yasuhiro Kodera,Kazuhiro Yoshida,Hiraku Kumamaru et al.
Yasuhiro Kodera et al.
Background: Although laparoscopic total gastrectomy (LTG) is considered a technically demanding procedure with safety issues, it has been performed in several hospitals in Japan. Data from a nationwide web-based data entr...
Efficacy and tolerability of ramucirumab monotherapy or in combination with paclitaxel in gastric cancer patients from the Expanded Access Program Cohort by the Korean Cancer Study Group (KCSG) [0.03%]
雷莫卢单药或联合紫杉醇治疗韩国扩展用药计划队列胃癌患者的有效性和耐受性：韩国癌症研究组(KCSG)报告
Minkyu Jung,Min-Hee Ryu,Do Youn Oh et al.
Minkyu Jung et al.
Background: Ramucirumab improves survival in gastric cancer patients. The efficacy and safety of ramucirumab outside of a clinical trial were evaluated using an expanded access program (EAP). ...
Total vs proximal gastrectomy for adenocarcinoma of the upper third of the stomach: a propensity-score-matched analysis of a multicenter western experience (On behalf of the Italian Research Group for Gastric Cancer-GIRCG) [0.03%]
胃上部腺癌的全胃切除与近端胃切除的倾向性匹配分析(意大利胃癌研究组-GIRCG成员)
Fausto Rosa,Giuseppe Quero,Claudio Fiorillo et al.
Fausto Rosa et al.
Background: The aim of this study is to compare surgical outcomes including postoperative complications and prognosis between total gastrectomy (TG) and proximal gastrectomy (PG) for proximal gastric cancer (GC). Propensi...
HOTAIR induces the ubiquitination of Runx3 by interacting with Mex3b and enhances the invasion of gastric cancer cells [0.03%]
HOTAIR通过与Mex3b的相互作用诱导Runx3泛素化并增强胃癌细胞侵袭能力
Meng Xue,Lu-Yi Chen,Wei-Jia Wang et al.
Meng Xue et al.
Background: Long non-coding RNAs (LncRNAs) exert their functions mainly by binding to their corresponding proteins. Runt-related transcription factor 3 (Runx3) is an important transcription factor that functions as a tumo...