Impact of adjuvant therapy on outcomes of cancer of the stomach and gastroesophageal junction in the real-world [0.03%]
胃癌和胃食管结合部癌新辅助治疗真实世界疗效分析
Steffen M Heckl,Hans-Michael Behrens,Ulrike Ebert et al.
Steffen M Heckl et al.
Background: Since the FLOT4 gastric cancer (GC) trial, the use of adjuvant chemotherapy has been perceived as limited and its added value questioned. We wanted to objectify this perception and reassess the value of adjuva...
Correction: Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer [0.03%]
订正：胃癌患者B淋巴细胞的空间组织和预后预测
Ryan Yong Kiat Tay,Manavi Sachdeva,Haoran Ma et al.
Ryan Yong Kiat Tay et al.
Circulating tumor DNA predicts clinical benefits of immune checkpoint blockade in HER2-negative patients with advanced gastric cancer [0.03%]
循环肿瘤DNA可预测HER2阴性晚期胃癌患者免疫检查点抑制剂的临床疗效
Mei He,Congcong Ji,Zhiwei Li et al.
Mei He et al.
Background: Immune checkpoint inhibitors (ICIs) are becoming more prominent in the treatment of gastric cancer (GC). However, predictive biomarkers of response to ICIs in HER2-negative patients remain incompletely underst...
A phase Ib study of photoimmunotherapy with ASP-1929 in combination with nivolumab for advanced gastric cancer (GE-PIT, EPOC1901) [0.03%]
ASP-1929光免疫疗法联合纳武利尤单抗治疗晚期胃癌Ib期研究（GE-PIT，EPOC1901）
Tomohiro Kadota,Rika Fujii,Shohei Koyama et al.
Tomohiro Kadota et al.
Background: Photoimmunotherapy with ASP-1929 (cetuximab conjugated to IRDye 700DX) and 690-nm red light has shown promising results, with a 43% objective response rate (ORR) in a phase IIa trial for recurrent head and nec...
The RNA-binding protein YTHDF3 affects gastric cancer cell migration and response to paclitaxel by regulating EZRIN [0.03%]
RNA结合蛋白YTHDF3通过调节EZRIN影响胃癌细胞迁移和紫杉醇敏感性
Patrícia Mesquita,Alexandre Coelho,Ana S Ribeiro et al.
Patrícia Mesquita et al.
Background: Gastric cancer (GC) is the fourth most common cause of cancer-related mortality and the fifth most common cancer worldwide. Despite efforts, the identification of biomarkers and new therapeutic approaches for ...
Paradoxical effects of adiposity and inflammation on immunotherapy efficacy in gastric cancer: novel insights from real-world data [0.03%]
胃癌免疫治疗疗效的肥胖和炎症悖论效应：真实世界数据的新见解
Li-Li Shen,Hua-Long Zheng,Zhi-Wei Zheng et al.
Li-Li Shen et al.
Background: Emerging studies suggest obesity may improve PD-1/PD-L1 inhibitor efficacy, correlating with prolonged survival, known as the 'obesity paradox'. However, the impact of this paradox and obesity-related chronic ...
Early angiographic changes after hemostatic radiotherapy for gastric cancer bleeding, mentioning the mechanism and potential immediate effects of the treatment [0.03%]
胃癌出血止血放射治疗后的早期血管造影变化及其机制和可能的即刻效应
Yuki Wada,Motoko Konno,Tomoki Tozawa et al.
Yuki Wada et al.
Although hemostatic radiotherapy has been reported as an effective treatment for gastric cancer bleeding, its mechanism and immediate effects remain unclear. We experienced a case of gastric cancer bleeding originating from both the whole g...
Predictive value of EBV-positivity in patients with gastric cancer treated with first-line nivolumab plus chemotherapy [0.03%]
Nivolumab联合化疗一线治疗胃癌患者中EBV阳性预后的预测价值
Hyung-Don Kim,So-Yeon Kim,Hyungeun Lee et al.
Hyung-Don Kim et al.
Background: Epstein-Barr virus (EBV) positivity is a potential predictive biomarker for immune checkpoint inhibitors (ICIs) in gastric cancer patients, but its value in first-line ICI-based chemotherapy remains unclear. T...
Function-preserving gastrectomy based on the sentinel node concept prevents osteosarcopenia in patients with gastric cancer [0.03%]
基于哨兵淋巴结概念的保功能胃切除术可预防胃癌患者的骨质疏松和肌肉减少症
Yuki Hirase,Takaaki Arigami,Daisuke Matsushita et al.
Yuki Hirase et al.
Background: Gastric cancer remains a significant global challenge, with conventional surgery for early gastric cancer often leading to post-gastrectomy complications. Sentinel node navigation surgery is being developed to...
Long-term natural course of patients with lymph node station 6 metastasis after pylorus-preserving gastrectomy [0.03%]
保脾门胃切除术后淋巴结6站转移患者的长期自然病程分析
Sa-Hong Kim,Franco José Signorini,Kyoyoung Park et al.
Sa-Hong Kim et al.
Background: Meticulous lymph node 6 station (LN#6) dissection is mandatory in pylorus-preserving gastrectomy (PPG), but can increase the risk of complications, such as postoperative delayed gastric emptying. With analyzin...