Q-TWiST analysis of first-line nivolumab plus chemotherapy versus chemotherapy in patients with advanced gastric cancer, gastroesophageal junction cancer, or esophageal adenocarcinoma from CheckMate 649: 4-year follow-up results [0.03%]
CheckMate 649一线纳武利尤单抗联合化疗对比单纯化疗治疗晚期胃癌、胃食管结合部癌和食管腺癌的Q-TWiST分析：4年随访结果
Daniel Lin,Wenying Quan,Marne Garretson et al.
Daniel Lin et al.
Background: Nivolumab plus chemotherapy demonstrated clinically significant improvement in quality-adjusted survival versus chemotherapy alone as first-line treatment for advanced non-HER2-positive gastric cancer, gastroe...
Effect of anamorelin on body weight in patients with gastric cancer-associated cachexia: an observational study [0.03%]
阿纳莫林对胃癌恶病质患者体重影响的观察研究
Yoshitomo Yanagimoto,Kotaro Yamashita,Ryohei Kawabata et al.
Yoshitomo Yanagimoto et al.
Background: In 2021, anamorelin, a ghrelin receptor agonist, was approved in Japan for cancer cachexia in select cancers, including gastric cancer. However, evidence regarding its efficacy and predictive factors in patien...
Efficacy of nodal dissection for locoregional gastric neuroendocrine carcinoma: a multicenter retrospective observational study [0.03%]
局部区域胃神经内分泌癌淋巴结清扫疗效的多中心回顾性观察研究
Yukinori Yamagata,Mitsuhiro Furuta,Akifumi Notsu et al.
Yukinori Yamagata et al.
Background: Gastric neuroendocrine carcinoma (NEC) is a rare and aggressive malignancy for which no standard treatment has been established for locoregional disease. This multicenter retrospective study aimed to evaluate ...
Comment on:"Gastric equivalent of the 'Holy Plane' to standardize the surgical concept of stomach cancer to mesogastric excision: updating Jamieson and Dobson's historic schema," Gastric cancer, 2021 Jan 2, by Hisashi Shinohara et al [0.03%]
对“制定以中胃切除为中心的标准胃癌手术概念的‘圣平面’的胃等效平面：更新Jamieson和Dobson的历史分型”的评论
Zhiping Huang,Wei Zhang
Zhiping Huang
Over the past three decades, the implementation of the complete mesocolic excision (CME)/total mesorectal excision (TME) technique in colorectal cancer surgery has significantly reduced local recurrence rates and improved tumor-related surv...
Evaluating boron neutron capture therapy as a potential treatment for unresectable gastrointestinal stromal tumors [0.03%]
评估硼中子俘获治疗不可切除的胃肠间质瘤的潜力
Seita Hagihara,Jun Arima,Yasuhiko Ueda et al.
Seita Hagihara et al.
Background: Boron neutron capture therapy selectively delivers the boron isotope 10B to tumors, where neutron irradiation induces a nuclear reaction that generates particle radiation, eradicating cancer cells. Imatinib an...
The oncogenic role of hypomethylated ZNF793 in gastric carcinoma: a focus on cell survival and stemness [0.03%]
胃癌中ZNF793低甲基化致癌作用：细胞生存和干性为重点的研究
Lingyan Jin,Hye-Yeong Jin,Meihui Li et al.
Lingyan Jin et al.
Background: Although genome-wide promoter CpG island hypermethylation of Epstein-Barr virus-associated gastric carcinoma (EBV GC) is well known, ZNF793 is rarely methylated in EBV GC but is frequently methylated in other ...
YAP as a therapeutic target to reverse trastuzumab resistance [0.03%]
针对人表皮生长因子受体2单克隆抗体耐药性的治疗靶点—— Yorkie同源物的筛选研究
Ah-Rong Nam,Kyoung-Seok Oh,Ju-Hee Bang et al.
Ah-Rong Nam et al.
Background: Trastuzumab resistance in HER2-positive cancers remains a significant clinical challenge with limited therapeutic options. Although the tumor-promoting role of the Yes-associated protein (YAP) pathway is well ...
Predicting response to patients with gastric cancer via a dynamic-aware model with longitudinal liquid biopsy data [0.03%]
基于纵向液体活检数据的动态感知模型预测胃癌患者的治疗反应
Zifan Chen,Jie Zhao,Yanyan Li et al.
Zifan Chen et al.
Background: Gastric cancer (GC) presents challenges in predicting treatment responses due to its patient-specific heterogeneity. Recently, liquid biopsies have emerged as a valuable data modality, offering essential cellu...
Positive association between anti-Helicobacter pylori IgG antibody titers and atrophic gastritis in a Latvian cohort [0.03%]
拉脱维亚队列中抗幽门螺杆菌IgG抗体滴度与萎缩性胃炎呈正相关
Joo Hyun Lim,Inese Poļaka,Danute Ražuka-Ebela et al.
Joo Hyun Lim et al.
Background: Although H. pylori is the most important risk factor for gastric cancer, the role of anti-H. pylori antibody titers in gastric carcinogenesis has not been investigated outside Asia. We aimed to analyze the rel...
Dihydrotestosterone-androgen receptor signaling suppresses EBV-positive gastric cancer through DNA demethylation-mediated viral reactivation [0.03%]
二氢睾酮-雄激素受体信号通过DNA去甲基化介导的病毒再激活抑制EB病毒感染的胃癌
Miyeon Cho,Hyeji Byun,Sun Hee Lee et al.
Miyeon Cho et al.
Background: Our Kaplan-Meier analysis reveals that gastric cancer patients with high androgen receptor (AR) expression demonstrate poorer survival outcomes compared to those with low AR expression, particularly in patient...