Management challenges and the role of adjuvant chemotherapy in remnant gastric cancer: an analysis of 313 patients from the KEGG multicenter observational study [0.03%]
残胃癌的治疗困境和辅助化疗的作用:KEGG多中心队列研究的313例分析
Ryosuke Okamura,Ryuhei Aoyama,Shigeru Tsunoda et al.
Ryosuke Okamura et al.
Background: Clinical findings and postoperative follow-up data on remnant gastric cancer (RGC) are limited due to its rarity. Additionally, the preoperative staging, radical surgery, and managing recurrence in RGC present...
Landscape of homologous recombination deficiency in gastric cancer and clinical implications for first-line chemotherapy [0.03%]
胃癌同源重组修复缺陷谱系及一线化疗的临床意义
Hiroshi Ichikawa,Masaki Aizawa,Yosuke Kano et al.
Hiroshi Ichikawa et al.
Background: Homologous recombination deficiency (HRD) is one of the crucial hallmarks of cancer. It is associated with a favorable response to platinum-based chemotherapy. We explored the distinctive clinicopathological f...
Increased cardiovascular disease risk among adolescents and young adults with gastric cancer [0.03%]
胃癌青少年和年轻成人患者的心血管疾病风险增加
Hea Lim Choi,Danbee Kang,Hyunsoo Kim et al.
Hea Lim Choi et al.
Background: Previous studies have investigated cardiovascular disease (CVD) risks in cancer patients, but there is limited knowledge concerning the CVD risk in adult and young adolescent (AYA) survivors of gastric cancer....
Functional genomics reveals an off-target dependency of drug synergy in gastric cancer therapy [0.03%]
功能基因组学揭示胃癌治疗中药物协同作用的脱靶依赖性
Ozen Leylek,Megan E Honeywell,Michael J Lee et al.
Ozen Leylek et al.
Background: Integrating molecular-targeted agents into combination chemotherapy is transformative for enhancing treatment outcomes in cancer. However, realizing the full potential of this approach requires a clear compreh...
Importance of duodenal stump reinforcement to prevent stump leakage after gastrectomy: a large-scale multicenter retrospective study (KSCC DELICATE study) [0.03%]
术后十二指肠残端补强可降低胃切除术后漏的发生率：一项多中心回顾性研究(KSCC DELICATE研究)
Akihiko Sano,Yoshiro Imai,Takahisa Yamaguchi et al.
Akihiko Sano et al.
Background: The significance of reinforcement of the duodenal stump with seromuscular sutures and the effectiveness of reinforced staplers in preventing duodenal stump leakage remain unclear. We aimed to explore the impor...
Chiara Molinari,Leonardo Solaini,Francesca Rebuzzi et al.
Chiara Molinari et al.
Background: The purpose of the study was to conduct a comprehensive genomic characterization of gene alterations, microsatellite instability (MSI), and tumor mutational burden (TMB) in submucosal-penetrating (Pen) early g...
Safety and feasibility of single-incision laparoscopic distal gastrectomy in overweight and obese gastric cancer patients: a propensity score-matched analysis [0.03%]
单孔腹腔镜远端胃癌根治术治疗超重和肥胖患者的安氏与可行性：倾向性评分匹配分析
Eunju Lee,Yun-Suhk Suh,Mira Yoo et al.
Eunju Lee et al.
Background: The technical challenges and safety concerns of single-incision laparoscopic gastrectomy for overweight and obese gastric cancer patients remain unclear. This study aimed to evaluate the safety and feasibility...
A systematic review on the effectiveness of robot-assisted minimally invasive gastrectomy [0.03%]
机器人辅助微创胃切除术有效性的系统评价研究论文
L Triemstra,R B den Boer,M M Rovers et al.
L Triemstra et al.
Background: Robot-assisted minimally invasive gastrectomy (RAMIG) is increasingly used as a surgical approach for gastric cancer. This study assessed the effectiveness of RAMIG and studied which stages of the IDEAL-framew...
Reply to letter to the editor: "5-year follow-up results of a JCOG1104 (OPAS-1) phase III noninferiority trial to compare 4 courses and 8 courses of S-1 adjuvant chemotherapy for pathological stage II gastric cancer" [0.03%]
对《JCOG1104（OPAS-1）Ⅲ期辅助化疗S-1四个疗程与八个疗程的非劣效性临床试验5年随访结果》来信的回复
Takaki Yoshikawa,Masanori Terashima,Junki Mizusawa
Takaki Yoshikawa
Gastric microbiome signature for predicting metachronous recurrence after endoscopic resection of gastric neoplasm [0.03%]
胃镜下切除胃肿瘤后预测异时复发的胃微生物组标志物
Ho-Kyoung Lee,Cheol Min Shin,Young Hoon Chang et al.
Ho-Kyoung Lee et al.
Background: Changes in gastric microbiome are associated with gastric carcinogenesis. Studies on the association between gastric mucosa-associated gastric microbiome (MAM) and metachronous gastric cancer are limited. This...