Volume of hepatoid component and intratumor M2 macrophages predict prognosis in patients with hepatoid adenocarcinoma of the stomach [0.03%]
肝样腺癌的肝样成分体积及瘤内M2型巨噬细胞浸润与患者预后的关系研究
Yoshiaki Taniguchi,Daisuke Kiyozawa,Kenichi Kohashi et al.
Yoshiaki Taniguchi et al.
Background: Hepatoid adenocarcinoma of the stomach (HAS), a subtype of gastric cancer (GC), includes multiple tumor components, such as enteroblastic and tubular adenocarcinoma components. However, which component mostly ...
Prognostic and predictive factors for the efficacy and safety of trastuzumab deruxtecan in HER2-positive gastric or gastroesophageal junction cancer [0.03%]
曲妥珠单抗deruxtecan治疗HER2阳性胃或胃食管交界部癌疗效和安全性的预后及预测因素分析
Amane Jubashi,Izuma Nakayama,Shigehiro Koganemaru et al.
Amane Jubashi et al.
Background: Trastuzumab deruxtecan (T-DXd) is an antibody-drug conjugate targeting HER2-positive gastric cancer or gastroesophageal junction cancer (GC/GEJC). Although effective, T-DXd has notable toxicities, including in...
Real-world effectiveness and safety of trastuzumab-deruxtecan in Japanese patients with HER2-positive advanced gastric cancer (EN-DEAVOR study) [0.03%]
针对HER2阳性晚期胃癌的曲妥珠单抗德鲁克斯在日本患者中的疗效和安全性（EN-DEAVOR研究）
Hisato Kawakami,Koki Nakanishi,Akitaka Makiyama et al.
Hisato Kawakami et al.
Background: Trastuzumab-deruxtecan (T-DXd) was approved for the treatment of HER2-positive patients with advanced gastric cancer in Japan based on the results of the DESTINY-Gastric01 trial. This study aimed to collect re...
Neoadjuvant chemotherapy in relation to long-term mortality in individuals cured of gastric adenocarcinoma [0.03%]
新辅助化疗与胃腺癌治愈患者的长期死亡率的关系
Wilhelm Leijonmarck,Fredrik Mattsson,Jesper Lagergren
Wilhelm Leijonmarck
Background: Late effects of chemotherapy could affect mortality amongst cancer survivors. This study aimed to clarify if neoadjuvant chemotherapy for gastric adenocarcinoma influences the long-term survival in individuals...
Circulating tumor DNA predicts recurrence and survival in patients with resectable gastric and gastroesophageal junction cancer [0.03%]
循环肿瘤DNA预测可切除胃癌和胃食管结合部癌患者的复发和生存情况
Cecilie Riis Iden,Salah Mohammad Mustafa,Nadia Øgaard et al.
Cecilie Riis Iden et al.
Background: Gastric and gastroesophageal junction (GEJ) cancer represents a significant global health challenge, with high recurrence rates and poor survival outcomes. This study investigates circulating tumor DNA (ctDNA)...
Prognostic significance of tertiary lymphoid structures in gastric neuroendocrine carcinoma with association to delta-like ligand 3 and neuroendocrine expressions [0.03%]
胃神经内分泌癌中三级淋巴器官的预后意义及其与Delta样配体3和神经内分泌标志物表达的相关性
Bokyung Ahn,Deokhoon Kim,Mi-Ju Kim et al.
Bokyung Ahn et al.
Background: Gastric neuroendocrine carcinomas (NECs) are rare cancers with highly aggressive behavior. Although tertiary lymphoid structures (TLSs) are well-known prognostic factors in various cancers, their role in gastr...
Clinical epidemiology of the endoscopic, laparoscopic, and surgical resection of malignant gastric tumors in Japan, 2014-2021: a retrospective study using open data from a national claims database [0.03%]
日本2014-2021年胃癌内镜、腹腔镜和手术切除的临床流行病学：一项使用全国索赔数据库公开数据的回顾性研究
Akahito Sako,Tomoyuki Yada,Keiichi Fujiya et al.
Akahito Sako et al.
Background: Gastric cancer is a common malignancy with a high incidence in East Asia. Gastric resection ranges from endoscopic resection to open total gastrectomy. However, nationwide data are lacking. ...
Lipolysis-stimulated lipoprotein receptor promote lipid uptake and fatty acid oxidation in gastric cancer [0.03%]
脂解刺激型载脂蛋白受体促进胃癌的脂质摄取和脂肪酸氧化
Kota Kawabata,Tsuyoshi Takahashi,Koji Tanaka et al.
Kota Kawabata et al.
Background: Lipolysis-stimulated lipoprotein receptor (LSR), a lipid receptor, is associated with cancer progression. However, detailed effects on intracellular metabolism are unclear. We aimed to elucidate the mechanism ...
Limitations of the cox proportional hazards model and alternative approaches in metachronous recurrence research [0.03%]
Cox比例风险模型在同期复发研究中的局限性以及替代方法
Lingyu Xu,Siqi Jiang,Tianyang Li et al.
Lingyu Xu et al.
The article by Shin et al. provides valuable insights into the correlation between the gastric mucosa-associated gastric microbiome (MAM) and metachronous recurrence. However, the use of the Cox proportional hazards model in their analysis ...
Multitask machine learning-based tumor-associated collagen signatures predict peritoneal recurrence and disease-free survival in gastric cancer [0.03%]
基于多任务机器学习的肿瘤相关胶原签名可预测胃癌患者的腹膜复发和无病生存期
Meiting Fu,Yuyu Lin,Junyao Yang et al.
Meiting Fu et al.
Background: Accurate prediction of peritoneal recurrence for gastric cancer (GC) is crucial in clinic. The collagen alterations in tumor microenvironment affect the migration and treatment response of cancer cells. Herein...