Pairwise analysis of plasma cell-free DNA before and after palliative second-line paclitaxel plus ramucirumab treatment in patients with metastatic gastric cancer [0.03%]
接受二线姑息性紫杉醇联合雷莫芦单抗治疗的转移性胃癌患者的治疗前和治疗后血浆游离DNA成对分析研究
Ji-Won Kim,Dong Soo Kyung,Won Yeong Ko et al.
Ji-Won Kim et al.
Background: This study compared plasma cell-free DNA (cfDNA) and tumor tissue DNA (ttDNA) to explore the clinical applicability of cfDNA in patients with metastatic gastric cancer (mGC) receiving palliative second-line pa...
Multicenter phase II study on the efficacy of an oral nutritional supplement containing eicosapentaenoic acid in advanced gastric cancer patients with cachexia [0.03%]
含有二十碳五烯酸的口服营养补充剂对恶病质晚期胃癌患者的多中心二期疗效研究
Ryohei Kawabata,Kazuhiro Nishikawa,Tomono Kawase et al.
Ryohei Kawabata et al.
Background: Cachexia is a common complication in advanced gastric cancer (AGC). Eicosapentaenoic acid (EPA) may ameliorate cachexia. This single-arm, phase II study assessed the potential benefit of an oral nutritional su...
Appetite-preserving gastrectomy (APG) for esophagogastric junction cancer: preserving the residual stomach as an endocrine organ [0.03%]
保存食欲的胃切除术（APG）用于食管胃交界处癌症：将剩余的胃作为内分泌器官保留下来
Naoki Hiki,Tadashi Higuchi,Koshi Kumagai et al.
Naoki Hiki et al.
Background: Loss of appetite following gastric cancer surgery, particularly total gastrectomy, significantly impacts patient quality of life due to the removal of the ghrelin-secreting region. We developed appetite-preser...
Simran Arjani,Hyein Jeon,Bhawneet Chadha et al.
Simran Arjani et al.
Gastric cancer is the fifth most common cancer worldwide and leptomeningeal carcinomatosis (LM) occurs in 0.06% of gastric cancers. As such, trials are difficult to power and quantitative analyses difficult to standardize. We composed a rev...
FERMT2 drives anoikis resistance and peritoneal metastasis by enhancing extracellular matrix deposition in gastric cancer [0.03%]
FERMT2通过增强胃癌中细胞外基质沉积来驱动脱落抵抗和腹膜转移
Chao He,Zheng Zhou,Yan Yang et al.
Chao He et al.
Peritoneal metastasis is a critical step in the progression of gastric cancer (GC), yet its underlying mechanisms remain poorly understood. Here, we identify FERMT2, a member of the Kindlin protein family, as a key regulator of anoikis resi...
Impact of histologically poorly cohesive phenotype as a prognostic factor in patients with pStage II/III gastric cancer undergoing adjuvant chemotherapy [0.03%]
组织学不规则凝聚表型作为辅助化疗的p期II / III胃癌患者中的预后因素的影响研究
Chikara Kunisaki,Sho Sato,Kohei Kasahara et al.
Chikara Kunisaki et al.
Background: Few studies have focussed on using histological phenotype to evaluate prognostic factors after adjuvant chemotherapy (AC) in patients with pStage II/III gastric cancer. We evaluated the impact of histological ...
Robotic and laparoscopic gastrectomy for gastric cancer: comparative insights into perioperative performance and three-year survival outcomes [0.03%]
胃癌的机器人和腹腔镜胃切除术：围手术期表现及三年生存率结果对比分析
Yuki Ushimaru,Takeshi Omori,Kazuyoshi Yamamoto et al.
Yuki Ushimaru et al.
Background: The primary treatment for gastric cancer (GC) is surgical resection, particularly for locally advanced cases. While laparoscopic gastrectomy (LG) has shown short- and long-term benefits, robotic gastrectomy (R...
The impact of ADAMTS14 genetic polymorphisms and its function on susceptibility to and prognosis of gastric cancer in a Chinese Han population [0.03%]
ADAMTS14基因多态性及其功能对中国汉族人群胃癌易感性和预后的影响
Pengyu Li,Jiacheng Dong,Yuan Li et al.
Pengyu Li et al.
Background: Single nucleotide polymorphisms (SNPs) are associated with various diseases, including gastric cancer. The ADAMTS14 gene is linked to multiple types of cancer. However, the relationship between ADAMTS14 and it...
Spatial organization of B lymphocytes and prognosis prediction in patients with gastric cancer [0.03%]
胃癌患者B淋巴细胞的空间组织和预后预测
Ryan Yong Kiat Tay,Manavi Sachdeva,Haoran Ma et al.
Ryan Yong Kiat Tay et al.
Background: Within the tumor microenvironment (TME), the association of B lymphocytes (B cells) with prognosis and therapy response in gastric cancer (GC) remains poorly characterized. We investigated the predictive and p...
The relationship between the gastric cancer microbiome and clinicopathological factors: a metagenomic investigation from the 100,000 genomes project and The Cancer Genome Atlas [0.03%]
胃癌微生物群与临床病理因素的关系：来自100,000基因组计划和癌症基因组图谱的宏基因组学研究
Mary E Booth,Henry M Wood,Mark A Travis;Genomics England Research Consortium;Phil Quirke et al.
Mary E Booth et al.
Background: Findings from previous gastric cancer microbiome studies have been conflicting, potentially due to patient and/or tumor heterogeneity. The intratumoral gastric cancer microbiome and its relationship with clini...