Diketopiperazines with In vivo Antimalarial Activity from Sponge-derived Streptomyces sp. 13-12-16 [0.03%]
由来源于海绵的链霉菌13-12-16产生的具有体内抗疟活性的二酮哌嗪类化合物
Loganathan Karthik,Arivarasan Vishnu Kirthi,Anirban Sengupta et al.
Loganathan Karthik et al.
Production of Biopharmaceutical Proteins from Scallop Hemocytes as a Bioreactor Using Improved Transfection Conditions [0.03%]
改进转染条件利用扇贝血细胞作为生物反应器生产生物药物蛋白质
Taro Tsuda,Akari Sakaguchi,Kazue Nagasawa
Taro Tsuda
Despite the widespread use of protein-based biopharmaceuticals, conventional production systems using mammalian cells and E.coli have some limitations, including the absence of post-translational modifications and potential risk of viral co...
Whole-genome Resequencing Reveals the Sex Determination System and Develops a Sex-specific Marker in Fat Greenling (Hexagrammos otakii) [0.03%]
全基因组重测序揭示虎绿石首鱼的性别决定机制并开发性别特异性分子标记
Duan Liao,Yangqing Zhang,Chunlong Miao et al.
Duan Liao et al.
Stronger Adaptability of Eukaryotic Communities than Prokaryotes in Seawater across an Extensive Salinity Gradient [0.03%]
在广泛的盐度梯度中，真核生物群落比原核生物群落具有更强的适应性
Shan Gao,Wei Zhao,Xiaoyan Guan et al.
Shan Gao et al.
Researching microbial ecology in extreme environments is crucial for advancing the basic ecological theory and exploring their potential applications in biotechnology. The salt drying system provides an accessible but harsh environment that...
Integrated Transcriptomic and Metabolomic Analyses Reveal Molecular Mechanism in Hybrid Crucian Carp (Carassius cuvieri♀ × Carassius auratus Red var♂) after Gut Infection with Aeromonas hydrophila L3-3 [0.03%]
整合转录组和代谢组分析揭示了感染豚草克列氏鱼（鲫鱼♀×红鲫鱼♂）肠道后分子机制
Fei Wang,Wei-Sheng Luo,Zi-Le Qin et al.
Fei Wang et al.
The microRNA Targeting Cu/Zn-SOD Increases the Susceptibility To WSSV Under Ammonia Stress in Pacific White Shrimp Litopenaeus vannamei [0.03%]
微RNA靶向Cu/Zn-SOD增加太平洋白虾氨应力下对WSSV的易感性
Dehui Sun,Xiuke Ouyang,Yan Liu et al.
Dehui Sun et al.
The high concentration of ammonia from deteriorated aquaculture environments and intensive culture system increases the susceptibility to white spot syndrome virus (WSSV) and causes high mortality in Pacific white shrimp Litopenaeus vanname...
Glycine Drives IMP Production in Hybrid Bream (Megalobrama Amblycephala ♀ × Culter Alburnus ♂) Via Concerted Action: Activating glycyl-tRNA Synthetase and Fueling the Pentose Phosphate Pathway [0.03%]
甘氨酸通过协同作用驱动团头鲂（♀ /♂）IMP的生成：活化甘氨酰-TRNA合成酶和为磷酸戊糖途径供能
Zhehua Xu,Weiting Zhang,Ruijie Zhan et al.
Zhehua Xu et al.
Correlation and Path Analysis of Shell Morphological and Body Mass Traits in Pacific Abalone (Haliotis discus hannai) [0.03%]
皱纹盘鲍壳形态性状和体重的关联分析及通径分析
Qi Luo,Xiaolong Gao,Mo Zhang et al.
Qi Luo et al.
Body mass, the primary target in the selective breeding of aquatic mollusks, is less intuitive to assess than shell morphological traits. To improve breeding efficiency, this study used path analysis to examine the influence of shell morpho...
Aquafeed Enrichment with Dictyota Dichotoma and Bacillus Coagulans: A Synergistic Strategy to Promote Growth, Immune Function, and Antioxidant Defensive Pathways in Cyprinus Carpio [0.03%]
采用Dictyota dichotoma和Bacillus coagulans富集的水产饲料：一种促进鲤鱼生长、免疫功能和抗氧化防御途径的协同策略
Karim E A Khalil,Mohamed F Abdelghany,Mohamed M El-Nawsany et al.
Karim E A Khalil et al.
This study evaluated the effects of dietary supplementation with Bacillus coagulans and/or the brown macroalga Dictyota dichotoma on growth, blood biochemical indices, immune responses, redox status, and gene regulation in common carp (Cypr...
Dynamic Transcriptomic Profiling of the HPG Axis Reveals Stage-Specific Regulatory Networks Underlying Natural Sex Change in Orange-Spotted Grouper (Epinephelus coioides) [0.03%]
动态转录组测序揭示斜带石斑鱼天然性别转变过程中下丘脑-垂体-性腺轴级联调控机制
Cheng Peng,Fengjuan Guo,Ningwen Zhang et al.
Cheng Peng et al.
Protogynous sex change in teleosts involves dramatic gonadal restructuring, governed by the hypothalamic-pituitary-gonadal (HPG) axis. Here, we established the dynamic regulatory atlas of the HPG axis during natural sex change in protogynou...