Modular and reconfigurable gas chromatography / differential mobility spectrometry (GC/DMS) package for detection of volatile organic compounds (VOCs) [0.03%]
用于检测挥发性有机化合物(VOCs)的模块化和可重构气相色谱/移动电位谱仪(GC/DMS)装置
Ilya M Anishchenko,Mitchell M McCartney,Alexander G Fung et al.
Ilya M Anishchenko et al.
Due to the versatility of present day microcontroller boards and open source development environments, new analytical chemistry devices can now be built outside of large industry and instead within smaller individual groups. While there are...
Utilizing Ion Mobility to Identify Isobaric Post-Translational Modifications: Resolving Acrolein and Propionyl Lysine Adducts by TIMS Mass Spectrometry [0.03%]
基于TIMS质谱的离子淌度技术分析同质异象型翻译后修饰：丙烯醛和丙酰化赖氨酸加合物的分离与鉴定
Jose D Gomez,Mark E Ridgeway,Melvin A Park et al.
Jose D Gomez et al.
Protein post-translational modifications provide critical proteomic details towards elucidating mechanisms of altered protein function due to toxic exposure, altered metabolism, or disease pathogenesis. Lysine propionylation is a recently d...
Towards the Analysis of High Molecular Weight Proteins and Protein complexes using TIMS-MS [0.03%]
基于TIMS质谱分析高分子量蛋白及蛋白复合物
Paolo Benigni,Rebecca Marin,Juan Camilo Molano-Arevalo et al.
Paolo Benigni et al.
In the present work, we demonstrate the potential and versatility of TIMS for the analysis of proteins, DNA-protein complexes and protein-protein complexes in their native and denatured states. In addition, we show that accurate CCS measure...
Supervised Semi-Automated Data Analysis Software for Gas Chromatography / Differential Mobility Spectrometry (GC/DMS) Metabolomics Applications [0.03%]
用于气相色谱/质子转移反应质谱代谢组学应用的监督半自动数据分析软件（GC/DMS）
Daniel J Peirano,Alberto Pasamontes,Cristina E Davis
Daniel J Peirano
Modern differential mobility spectrometers (DMS) produce complex and multi-dimensional data streams that allow for near-real-time or post-hoc chemical detection for a variety of applications. An active area of interest for this technology i...
Gated Trapped Ion Mobility Spectrometry Coupled to Fourier Transform Ion Cyclotron Resonance Mass Spectrometry [0.03%]
基于傅里叶变换离子回旋共振质量谱的门控陷阱离子漂移管联用技术
Mark E Ridgeway,Jeremy J Wolff,Joshua A Silveira et al.
Mark E Ridgeway et al.
Analysis of molecules by ion mobility spectrometry coupled with mass spectrometry (IMS-MS) provides chemical information on the three dimensional structure and mass of the molecules. The coupling of ion mobility to trapping mass spectromete...
Isomer Separation of Polybrominated Diphenyl Ether Metabolites using nanoESI-TIMS-MS [0.03%]
基于nanoESI-TIMS-MS的多溴代二苯醚代谢物异构体分离研究
Kendra J Adams,Dennise Montero,Diana Aga et al.
Kendra J Adams et al.
In this paper, high-resolution nano-electrospray ionization-trapped ion mobility spectrometry coupled to mass spectrometry (nESI-TIMS-MS) is used for the study of hydroxylated polybrominated diphenyl ether (OH-PBDE) metabolites. In particul...
Jessica L Staymates,Matthew E Staymates,Jeffrey Lawrence
Jessica L Staymates
Sample collection for Ion Mobility Spectrometry (IMS) analysis is typically completed by swiping a collection wipe over a suspect surface to collect trace residues. The work presented here addresses the need for a method to measure the coll...
Theoretical predictor for candidate structure assignment from IMS data of biomolecule-related conformational space [0.03%]
基于生物分子构象空间的离子淌度数据的理论结构指派预测器
Emily R Schenk,Frederic Nau,Francisco Fernandez-Lima
Emily R Schenk
The ability to correlate experimental ion mobility data with candidate structures from theoretical modeling provides a powerful analytical and structural tool for the characterization of biomolecules. In the present paper, a theoretical wor...
Towards unsupervised polyaromatic hydrocarbons structural assignment from SA-TIMS-FTMS data [0.03%]
基于SA-TIMS-FTMS数据的多环芳香烃结构指认研究进展
Paolo Benigni,Rebecca Marin,Francisco Fernandez-Lima
Paolo Benigni
With the advent of high resolution ion mobility analyzers and their coupling to ultrahigh resolution mass spectrometers, there is a need to further develop a theoretical workflow capable of correlating experimental accurate mass and mobilit...
Jessica L Staymates,Shahram Orandi,Matthew E Staymates et al.
Jessica L Staymates et al.
This paper describes a method for combining direct chemical analysis of latent fingerprints with subsequent biometric analysis within a single sample. The method described here uses ion mobility spectrometry (IMS) as a chemical detection me...