Correction: Intravenously delivered mesenchymal stem cells prevent microvascular obstruction formation after myocardial ischemia/reperfusion injury [0.03%]
纠正：间充质干细胞的静脉递送可在心肌缺血/再灌注损伤后防止微血管阻塞形成
Junzhuo Wang,Ziwei Chen,Qing Dai et al.
Junzhuo Wang et al.
Published Erratum
Basic research in cardiology. 2026 Apr 9. DOI:10.1007/s00395-026-01170-z 2026
Genetic background is associated with distinct patterns of proarrhythmogenic remodeling leading to atrial fibrillation in pigs with ischemic heart failure [0.03%]
遗传背景与导致心力衰竭猪房颤发生的促心律失常重构模式相关
Zhihao Zhang,Julia Vlcek,Christina Heger et al.
Zhihao Zhang et al.
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, driven by electrical and structural remodeling that promotes proarrhythmic substrates. Interindividual variability in susceptibility to remodeling triggers, such as m...
Comparing anti-platelet and anti-thrombin therapies in the ischaemia-reperfusion injured coronary microcirculation of healthy and diabetic mice [0.03%]
健康小鼠和糖尿病小鼠冠状微循环缺血再灌注损伤的抗血小板与抗凝治疗比较研究
Joanne L Mitchell,Juma El-Awaisi,Dean Kavanagh et al.
Joanne L Mitchell et al.
Patients with type 2 diabetes mellitus (T2DM) face increased risk of heart failure after myocardial infarction (MI), despite successful PCI and dual anti-platelet therapy (DAPT), due to coronary microvascular obstruction. This study examine...
Pharmacological reactivation of autophagic flux by natural compounds or synthetic cell-permeable peptide prevents doxorubicin-induced cardiomyopathy [0.03%]
天然化合物或合成细胞可渗透肽的药理学再活化自噬流量可预防多柔比星诱导的心肌病
Leonardo Schirone,Daniele Vecchio,Valentina Valenti et al.
Leonardo Schirone et al.
Therapeutic strategies to limit doxorubicin (DOX)-induced cardiomyopathy are still limited due to incomplete characterization of the underlying molecular mechanisms. The exogenous activation of autophagy was reported to exert cardioprotecti...
A high-fat diet nutritional intervention reprograms cardiac metabolism and improves systolic function in a pig model of heart failure with reduced ejection fraction [0.03%]
高脂饮食营养干预可重构射血分数降低型心力衰竭猪模型的心肌代谢并改善收缩功能
Carlos Galán-Arriola,Daniel Pérez-Camargo,Alessia Ferrarini et al.
Carlos Galán-Arriola et al.
Most forms of heart failure are characterized by a metabolic switch from the use of fatty acids to glucose as the main fuel source for ATP generation in the myocardium. Whether metabolic reprogramming is a therapeutic target remains controv...
ATP5A1 succinylation as a key driver for the transition of myocardial ischemia to development of heart failure [0.03%]
心肌缺血向心脏衰竭发展的关键驱动因素是ATP5A1琥珀酰化
Lujing Jiang,Shanshan Chen,Senlin Li et al.
Lujing Jiang et al.
Myocardial ischemia is the common etiology of heart failure (HF). However, the precise molecular mechanisms that govern the ischemic myocardium into HF remain poorly defined. Selective accumulation of succinate is a hallmark of ischemia. Su...
Short-term blockade of E-prostanoid 3 receptor mitigates necroinflammation and ameliorates ischemia/reperfusion- and doxorubicin-induced acute myocardial injury [0.03%]
短期阻断E型前列腺素受体3减轻坏死性炎症并改善心肌缺血/再灌注和多柔比星致急性损伤
Dong He,Yequn Chen,Jiahui Ge et al.
Dong He et al.
E-prostanoid 3 receptor (EP3) plays an important role in maintaining normal heart growth and development, and its activation may drive acute inflammation and influence intracellular Ca2+ level. The effects of targeting EP3 on myocardial inj...
Insights in ischemia/reperfusion injury and cardioprotection: neglected and emerging pathways and therapeutic targets for a personalized therapy [0.03%]
缺血/再灌注损伤与心肌保护的研究进展：被忽视及新出现的信号通路和治疗靶点为个体化医疗提供可能
Pasquale Pagliaro,C Penna,S Femminò et al.
Pasquale Pagliaro et al.
Despite extensive preclinical research identifying molecular targets and cardioprotective strategies, translation into effective clinical therapies remains challenging. Cardioprotection aims to mitigate ischemia/reperfusion injury (IRI) by ...
PARKIN overexpression confers cardioprotection via suppressing the mtDNA-cGAS-STING axis in myocardial ischemia/reperfusion injury [0.03%]
Parkin过表达通过抑制线粒体DNA-cGAS-STING轴在心肌缺血/再灌注损伤中发挥心脏保护作用
Yujing Li,Yuhan Wang,Hao Zhang et al.
Yujing Li et al.
Myocardial ischemia/reperfusion (I/R) injury is exacerbated by inflammation, yet the upstream triggers of this cascade and their amenability to therapeutic intervention remain unclear. The cyclic GMP-AMP synthase-stimulator of interferon ge...
Time course of early and delayed myocardial protection induced by vagal nerve stimulation preconditioning [0.03%]
迷走神经预刺激的早期和延迟的心肌保护作用的时间进程研究
Verena B Franco-Riveros,Jazmín Kelly,Timoteo Marchini et al.
Verena B Franco-Riveros et al.
We previously reported that pre-ischemic vagus nerve stimulation (VNS) protects against myocardial ischemia, resembling classical ischemic preconditioning (cPC). This study investigates the time course and mechanisms underlying VNS-induced ...