Memantine: updates from the past decade and implications for future novel therapeutic applications [0.03%]
(memantine): 过去十年的更新及对未来新型治疗应用的意义
Wojciech Danysz,Niels Hansen,Jens Wiltfang et al.
Wojciech Danysz et al.
This review provides an update on advances during the past decade in our knowledge of the pharmacology and clinical use of memantine. It covers aspects related to preclinical research, such as new findings about the mechanism of action, and...
Q-MIND: enhancing ADHD diagnosis using quantum machine learning for advanced neuroimaging analysis [0.03%]
基于量子机器学习的注意缺陷多动障碍诊断方法-Q-MIND
Bhawna Jain,Astha Varshney,Muskaan Vithal
Bhawna Jain
Attention deficit hyperactivity disease (ADHD) is a neurobehavioural disorder of heterogeneous nature that is common among children and adolescents. It is marked by symptoms such as inattention, hyperactivity, and impulsivity that substanti...
Fabrizio Stocchi,Eleonora Annese,Fabiana Radicati et al.
Fabrizio Stocchi et al.
Dysphagia is a manifestation of swallowing dysfunction frequently observed in Parkinson's disease (PD). It can lead to serious clinical consequences when the patient experience aspiration or chest infections. Even in less severe cases, dysp...
The chain mediating role of social support and perceived stress on the relationship between depression severity and quality of life in patients with major depressive disorder [0.03%]
社会支持和心理应激在抑郁症严重程度与生活质量关系间的链式中介作用分析
Changlin Zhang,Xue Tian,Meijuan Li et al.
Changlin Zhang et al.
Major depressive disorder (MDD) is a prevalent and debilitating mental illness that significantly impacts patients' health and quality of life. This study aims to investigate the mediating effect of social support and perceived stress in th...
Apomorphine differentially engages the cAMP and β-arrestin signaling pathways relative to dopamine at human dopamine receptors [0.03%]
阿朴吗啡与多巴胺在作用于人类多巴胺受体时的不同之处：阿朴吗啡激活cAMP和β- arrestin信号通路的研究
Brittney Yegla,Jonathan Rubin,Mindy Grall et al.
Brittney Yegla et al.
Apomorphine is the only dopamine agonist used to treat Parkinson disease with similar efficacy to levodopa. Its original characterization as a dopamine agonist was based on its receptor binding profile and capacity to recruit G proteins; ho...
Alcohol withdrawal and the sigma receptor: exploring the link between withdrawal and cognitive impairment [0.03%]
酒精戒断与sigma受体：探讨戒断与认知障碍之间的联系
Ajay V Lokhande,Smeeta S Sadar,Niraj S Vyawahare et al.
Ajay V Lokhande et al.
Alcohol withdrawal syndrome is increasingly recognized as a significant public health concern in India and worldwide, highlighting the pressing need for innovative therapeutic strategies. The Sigma-1 receptor system has recently garnered at...
Pedro J Garcia Ruiz
Pedro J Garcia Ruiz
Evolutionary approach tries to explain several aspects of neurological diseases under the perspective of evolution. Evolutive bottle-neck may explain some aspects of neurodegenerative diseases. Additionally, a number of genetic alleles may ...
Predictors of cognitive performance in idiopathic adult-onset dystonia [0.03%]
特发性成年发病扭转痉挛患者认知功能障碍的影响因素分析
Vittorio Velucci,Marcello Mario Mascia,Laura Avanzino et al.
Vittorio Velucci et al.
Cognitive dysfunction is increasingly recognised as a potential non-motor feature of the idiopathic adult-onset dystonia (IAOD) phenotype. However, evidence from large cohort studies is lacking, as previous research has been limited to smal...
Correction: New trends in the research of psychiatric and neurodegenerative diseases: a tribute to Melita Salkovic-Petrisic [0.03%]
订正：精神病和神经退行性疾病研究新趋势：献给梅丽塔·萨尔科维奇-彼得里西女士
Jelena Osmanović Barilar
Jelena Osmanović Barilar
Exploring the relationship between health behavior and sleep quality: preliminary insights from ECG-derived sleep analysis [0.03%]
基于心电导联睡眠分析的健康行为与睡眠质量关系探究初步报告
Claudia Traunmüller,Andreas R Schwerdtfeger
Claudia Traunmüller
Correlations between sleep quality, health behavior, and metabolic variables are empirically well documented. This study investigated a novel algorithm to determine sleep stages by leveraging ECG data. The aim was to examine whether this al...