Alessandra Fanciulli,Fabian Leys,Günter Höglinger et al.
Alessandra Fanciulli et al.
Cardiovascular autonomic failure is a frequent non-motor feature of Parkinson's disease (PD) that affects up to one third of individuals from the premotor to the advanced stages of the disease, with major diagnostic, therapeutic and prognos...
Parkinson's disease subtypes and their relationship to dementia with Lewy bodies: a comparative neuroimaging analysis based on nigrostriatal degeneration [0.03%]
基于黑质纹状体变性的帕金森病亚型及其与路易体痴呆的关系的比较影像学分析
Keizo Sugaya,Tomoya Kawazoe,Yasuhiro Nakata et al.
Keizo Sugaya et al.
This study hypothesized a subtype of Parkinson's disease (PD) sharing features of nigrostriatal degeneration with dementia with Lewy bodies (DLB) to account for the difficulty of differentiating the two diseases and explored their relations...
Mark A Colijn
Mark A Colijn
A variety of neuropsychiatric symptoms have been reported in tuberous sclerosis. Although psychosis may occur, little has been written about this topic. This systematic review sought to characterize the nature of tuberous sclerosis-associat...
Kynurenine metabolites unchanged after multinutrient supplementation in children with ADHD: a secondary data analysis from the MADDY study [0.03%]
多营养素补充对注意缺陷多动障碍儿童犬尿氨酸代谢物的影响:来自MADDY研究的二次数据分析结果
Alisha M Bruton,Hayleigh K Ast,Lydia Norby-Adams et al.
Alisha M Bruton et al.
Attention-deficit/hyperactivity disorder (ADHD) affects up to 10% of children, often presenting with emotional dysregulation (irritability, anger). The kynurenine pathway, by which the amino acid tryptophan is converted into both neuroprote...
Distinct plasma inflammatory signatures reflect disease severity and progression in progressive supranuclear palsy: a prospective cohort study [0.03%]
血浆炎症特征反映进行性核上性麻痹的疾病严重程度和进展:前瞻性队列研究
Ryul Kim,Heejung Kim,Seungmin Lee et al.
Ryul Kim et al.
Neuroinflammation is increasingly recognized as a key driver of progressive supranuclear palsy (PSP), but the role of blood inflammatory markers remains unrevealed. This prospective cohort study aimed to characterize blood inflammatory prot...
Precision prevention for neurodegenerative diseases: lessons learnt from Alzheimer's disease translated into perspectives for Parkinson's disease [0.03%]
精准预防神经退行性疾病:阿尔茨海默病的经验教训及其对帕金森病的启示
Sibylle Béchet,Morgan Leonard,Esther Ademola et al.
Sibylle Béchet et al.
Population ageing is posing significant challenges for healthcare systems and societies worldwide. Neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease, are among the leading contributors to disability, dependen...
Neuropathology in genetic Parkinson's disease: a focused review of pathological and clinical findings [0.03%]
遗传性帕金森病的神经病理学:病理和临床发现的专题回顾
Pedro Melo Barbosa,Jacy Bezerra Parmera,Thomas T Warner
Pedro Melo Barbosa
Parkinson's disease (PD) is a neurodegenerative disorder with a complex interaction between genetic and environmental causal factors. The role of Lewy body (LB) pathology (Lewy bodies and neurites) in genetic PD remains unclear, as some gen...
Is there a link between multiple sclerosis and Alzheimer disease? A critical note [0.03%]
关于多发性硬化和阿尔茨海默病之间的联系了吗?一条批判性的注释
Kurt A Jellinger
Kurt A Jellinger
Multiple sclerosis (MS) and Alzheimer disease (AD) are two neurological disorders that represent a major health problem, as they pose an enormous burden to the patients' quality of life. Although no cure is available, due to recent therapeu...
Evaluation of increased oxidative stress in the brain of patients with early Alzheimer's disease by 64Cu-ATSM PET/MRI [0.03%]
64Cu-ATSM PET/MRI用于评估轻度阿尔茨海默病患者脑内氧化应激增加
Yanan Huang,Masamichi Ikawa,Munenobu Nogami et al.
Yanan Huang et al.
We aimed to compare brain oxidative stress (OS) levels between patients with early Alzheimer's disease (eAD) and age-matched cognitively normal (CN) individuals using 64Cu-diacetyl-bis(N4-methylthiosemicarbazone) (64Cu-ATSM) PET/MRI. Thirty...
Influence of the level of education on cognitive function in Parkinson's disease [0.03%]
教育程度对帕金森病患者认知功能的影响
Diego Santos-García,Teresa de Deus Fonticoba,Carlos Cores Bartolomé et al.
Diego Santos-García et al.
Level of Education (LoE) is widely used as an indicator of cognitive reserve and is associated with risk of dementia. The aim of the present study was to know the influence of the LoE on cognitive function (CF) in patients with Parkinson´s...