Disruption of gamma-delta relationship related to working memory deficits in first-episode psychosis [0.03%]
首次精神病发作与工作记忆障碍相关的gamma-δ失联现象研究
Pascal Missonnier,Anne Prévot,François R Herrmann et al.
Pascal Missonnier et al.
Working memory (WM) deficits constitute a core symptom of schizophrenia. Inadequacy of WM maintenance in schizophrenia has been reported to reflect abnormalities in the excitation/inhibition (E/I) balance between pyramidal neurons and parva...
Predict cognitive decline with clinical markers in Parkinson's disease (PRECODE-1) [0.03%]
预测帕金森病认知下降的临床标志物(PRECODE-1)
Heather Wilson,Gennaro Pagano,Tayyabah Yousaf et al.
Heather Wilson et al.
Over the course of the disease, about 80% of Parkinson's disease patients will develop cognitive impairment. However, predictive factors associated with cognitive decline are still under investigation. Here, we investigated which clinically...
The bimodal mechanism of interaction between dopamine and mitochondria as reflected in Parkinson's disease and in schizophrenia [0.03%]
多巴胺与线粒体相互作用的双峰模式在帕金森病和精神分裂症中的体现
Dorit Ben-Shachar
Dorit Ben-Shachar
Parkinson's disease (PD) and schizophrenia (SZ) are two CNS disorders in which dysfunctions in the dopaminergic system and mitochondria are major pathologies. The symptomology of both, PD a neurodegenerative disorder and SZ a neurodevelopme...
Continuous theta burst stimulation increases contralateral mu and beta rhythms with arm elevation: implications for neurorehabilitation [0.03%]
连续theta波爆发刺激增加上肢抬高时对侧的mu和beta节律：神经康复的意义
Ana Dionísio,Rita Gouveia,Isabel Catarina Duarte et al.
Ana Dionísio et al.
The study of the physiological effects underlying brain response to transcranial magnetic stimulation is important to understand its impact on neurorehabilitation. We aim to analyze the impact of a transcranial magnetic stimulation protocol...
High-resolution chromosomal microarray analysis for copy-number variations in high-functioning autism reveals large aberration typical for intellectual disability [0.03%]
高功能自闭症拷贝数变异的高分辨率染色体微阵列分析发现典型的智力障碍异常区域
Anna Maria Werling,Edna Grünblatt,Beatrice Oneda et al.
Anna Maria Werling et al.
Copy-number variants (CNVs), in particular rare, small and large ones (< 1% frequency) and those encompassing brain-related genes, have been shown to be associated with neurodevelopmental disorders like autism spectrum disorders (ASDs), att...
Agricultural work and reduced circulating uric acid are both associated with initial hospital admission for Parkinson's disease [0.03%]
农业劳动和循环尿酸降低都与首次帕金森病住院有关
Hanxiang Liu,Xianwen Wei,Wen Yang et al.
Hanxiang Liu et al.
Monoamine oxidase type B inhibitors act in Parkinson's disease (PD) via potentiation of dopamine, but may also have neuroprotective effects by reducing oxidative damage. Oxidative damage is also a feature of environmental toxins, including ...
András Salamon,Dénes Zádori,László Szpisjak et al.
András Salamon et al.
Parkinson's disease (PD) is the second most common neurodegenerative disease worldwide. Behind the symptoms there is a complex pathological mechanism which leads to a dopaminergic cell loss in the substantia nigra pars compacta. Despite the...
Frequency of different subtypes of cervical dystonia: a prospective multicenter study according to Col-Cap concept [0.03%]
采用Col-Cap概念的颈部肌张力障碍亚型流行病学的前瞻性多中心研究
Wolfgang H Jost,Laurent Tatu,Sanjay Pandey et al.
Wolfgang H Jost et al.
Patients with cervical dystonia (CD) may present with head and/or neck movements in the coronal, sagittal or transverse plane. According to the Col-Cap concept, CD postures are classified in torti-, latero-, ante- and retrocollis/caput patt...
Monika Pupíková,Irena Rektorová
Monika Pupíková
We evaluated the therapeutic effects of non-pharmacological interventions (cognitive training, physical activity, and non-invasive brain stimulation) on cognitive symptoms in Parkinson's disease. A comprehensive literature search for non-ph...
Neuroprotection of dopamine neurons by xenon against low-level excitotoxic insults is not reproduced by other noble gases [0.03%]
氙气对微弱的兴奋性神经毒损伤的黑质多巴胺能神经元保护作用其他惰性气体无法替代
Déborah Le Nogue,Jérémie Lavaur,Aude Milet et al.
Déborah Le Nogue et al.
Using midbrain cultures, we previously demonstrated that the noble gas xenon is robustly protective for dopamine (DA) neurons exposed to L-trans-pyrrolidine-2,4-dicarboxylate (PDC), an inhibitor of glutamate uptake used to generate sustaine...