Sergey A Lashin,Yury G Matushkin
Sergey A Lashin
In this paper we consider the recent advances in methodology for modeling of prokaryotic communities evolution and new features of the software package "Haploid evolutionary constructor" (http://evol-constructor.bionet.nsc.ru). We show the ...
Computer System for Analysis of Molecular Evolution Modes (SAMEM): analysis of molecular evolution modes at deep inner branches of the phylogenetic tree [0.03%]
分子进化模式分析计算机系统（SAMEM）：用于深入探讨系统树内部支链的分子进化模式分析系统
Konstantin V Gunbin,Valentin V Suslov,Mikhail A Genaev et al.
Konstantin V Gunbin et al.
SAMEM (System for Analysis of Molecular Evolution Modes), a web-based pipeline system for inferring modes of molecular evolution in genes and proteins (http://pixie.bionet.nsc.ru/samem/), is presented. Pipeline 1 performs analyses of protei...
ExpertDiscovery and UGENE integrated system for intelligent analysis of regulatory regions of genes [0.03%]
基于ExpertDiscovery和UGENE的基因调控区域智能分析系统
Y Y Vaskin,I V Khomicheva,E V Ignatieva et al.
Y Y Vaskin et al.
The task of automatic extraction of the hierarchical structure of eukaryotic gene regulatory regions is in the junction of the fields of biology, mathematics and information technologies. A solution of the problem involves understanding of ...
J E van den Ende
J E van den Ende
Illuminator: increasing synergies between medicinal and computational chemists [0.03%]
Illuminator：增加医药和计算化学领域之间的协同合作
Alberto Gobbi,Matthew Lardy,Sun Hee Kim et al.
Alberto Gobbi et al.
We present Illuminator, a user-friendly web front end to computational models such as docking and 3D shape similarity calculations. Illuminator was specifically created to allow non-experts to design and submit molecules to computational ch...
Jacqueline M Hughes-Oliver,Atina D Brooks,William J Welch et al.
Jacqueline M Hughes-Oliver et al.
ChemModLab, written by the ECCR @ NCSU consortium under NIH support, is a toolbox for fitting and assessing quantitative structure-activity relationships (QSARs). Its elements are: a cheminformatic front end used to supply molecular descrip...
Improving usability and accessibility of cheminformatics tools for chemists through cyberinfrastructure and education [0.03%]
通过网络基础设施和教育改善化学信息工具的易用性和可访问性以适应化学家的需求
Rajarshi Guha,Gary D Wiggins,David J Wild et al.
Rajarshi Guha et al.
Some of the latest trends in cheminformatics, computation, and the world wide web are reviewed with predictions of how these are likely to impact the field of cheminformatics in the next five years. The vision and some of the work of the Ch...
Fragment-based molecular design of new competitive dengue Den2 Ns2b/Ns3 inhibitors from the components of fingerroot (Boesenbergia rotunda) [0.03%]
从山柰成分中设计新型登革病毒den2 ns2b/ns3竞争性抑制剂
Neni Frimayanti,Sharifuddin M Zain,Vannajan Sanghiran Lee et al.
Neni Frimayanti et al.
Gene expression data analysis using multiobjective clustering improved with SVM based ensemble [0.03%]
基于SVM的集成优化的多目标聚类在基因表达数据分析中的应用
Anirban Mukhopadhyay,Ujjwal Maulik,Sanghamitra Bandyopadhyay
Anirban Mukhopadhyay
Microarray technology facilitates the monitoring of the expression levels of thousands of genes over different experimental conditions simultaneously. Clustering is a popular data mining tool which can be applied to microarray gene expressi...
Dikla Dotan-Cohen,Dana Moonshine,Moshe Natan et al.
Dikla Dotan-Cohen et al.
The low reproducibility of differential expression of individual genes in microarray experiments has led to the suggestion that experiments be analyzed in terms of gene characteristics, such as GO categories or pathways, in order to enhance...