The deficit of oligodendrocyte family cells in layer 3 of the dorsal anterior cingulate cortex in schizophrenia: possible interactions with dysfunction and altered microanatomy [0.03%]
精神分裂症中背内侧前额叶皮层第3层少突细胞家族缺陷:与功能障碍和微结构异常的相互作用可能性
N S Kolomeets,N A Uranova
N S Kolomeets
Current concepts suggest a close relationship between dysfunction of neuronal circuits, abnormalities of brain myelination, and alterations in the structure and function of oligodendrocyte lineage cells. Previously, we reported a significan...
Efficacy and EEG-ECG mechanisms of taVNS combined with TEAS for negative symptoms of schizophrenia: a protocol for a 2 × 2 factorial randomized controlled trial [0.03%]
经颅电刺激联合舌咽神经刺激改善精神分裂症阴性症状的有效性和EEG-ECG机制:一项双因素随机对照试验的方案研究
Shumin Zhang,Yi Gong,Bingkui Zhang et al.
Shumin Zhang et al.
Negative symptoms of schizophrenia (NSS) represent a core feature of the disorder associated with substantial disease burden and poor functional prognosis, yet current therapeutic options remain limited. Given this unmet clinical need, we w...
(Anti)-mattering and its association with child maltreatment and loneliness: evidence from the German versions of the general mattering and anti-mattering scales [0.03%]
(反)重要性与儿童虐待和孤独感的关联:来自德国版普遍重要性和非重要性量表的证据
Matthias A Reinhard,Djuna Schwedler,Maxime Wendlinger et al.
Matthias A Reinhard et al.
Background: Mattering and anti-mattering are closely associated with mental health outcomes, including loneliness. Mattering describes the perceived sense of being important to others, whereas anti-mattering reflects feel...
Reciprocal relationships between self-stigma, psychological distress, and suicidality among individuals with schizophrenia: a random intercept cross-lagged panel model with a one-year follow-up [0.03%]
精神分裂症患者自我歧视、心理痛苦和自杀意念之间的互惠关系:一年随访的随机截距交叉滞后模型分析
Yun-Ling Chen,Hsin-Chi Tsai,Hsiao-Wei Huang et al.
Yun-Ling Chen et al.
Self-stigma, psychological distress, and suicidality are interrelated constructs in schizophrenia, yet their temporal relationships remain unclear. This study examined reciprocal relationships among self-stigma, psychological distress, and ...
Global burden of depressive disorders from 1990 to 2021: temporal trends, COVID-19 Impact, and projections to 2050 [0.03%]
1990年至2021年全球抑郁症疾病负担:时间趋势、新冠疫情的影响及2050年的预测
Jiaoqiong Guan,Fei Wen,Juqing Deng et al.
Jiaoqiong Guan et al.
Depressive disorders constitute a leading global cause of disability, yet comprehensive evidence regarding their long-term trends, socioeconomic disparities, and the impact of the COVID-19 pandemic remains limited. This study aimed to inves...
Variables associated with self- and proxy-perceived difficulties in independent living for patients with bipolar disorder and comorbid dementia [0.03%]
与双相情感障碍伴发痴呆患者独立生活困难相关的自评和他评变量
Chia-Chih Lu,Yi-Ching Wang,Posen Lee et al.
Chia-Chih Lu et al.
Background: Identifying variables associated with difficulties in independent living may help optimize intervention, as only 50% of individuals with bipolar disorder alone achieve residential independence. This proportion...
Accelerated aging in schizophrenia: integrating epigenetic clocks, telomere dynamics, senescence-associated secretory phenotype, and oxidative stress [0.03%]
整合表观遗传钟、端粒动力学、衰老相关分泌表型和氧化应激探讨精神分裂症的加速衰老现象
Xuan Ge,Chenying Jiang,Chaoran Wu et al.
Xuan Ge et al.
Schizophrenia (SCZ) is a severe and chronic neuropsychiatric disorder associated with substantially shortened life expectancy and early onset of age-related comorbidities. Mounting evidence from physical health, brain structure, and cogniti...
Frequency-decomposed EEG microstate analysis reveals altered cross-frequency coordination in adolescent major depressive disorder [0.03%]
频率分解的EEG微状态分析揭示了青少年重大抑郁障碍的跨频协同失调现象
Shimin Sun,Wentao Cheng,Yujiao Wen et al.
Shimin Sun et al.
Adolescent major depressive disorder (MDD) involves alterations in large‑scale brain network dynamics. However, conventional EEG microstate studies typically rely on broadband signals and overlook frequency‑band specificity and cross‑fre...
Association between thyroid hormone T3 and aggression in drug-naïve schizophrenia: a directed acyclic graph analysis [0.03%]
无药物治疗的首次发作精神分裂症患者中T3与攻击行为的关系:定向无环图分析
Cong Yao,Changyong Jiang,Meng Zhang et al.
Cong Yao et al.
Background: Aggression is a major clinical issue in schizophrenia, but its biological basis remains unclear. This study examined the relationship between thyroid hormones, psychiatric symptoms, and aggression in drug-naï...
Abnormal emotional intensity processing in individuals at clinical high risk for psychosis: evidence from event-related potentials [0.03%]
临床高危个体的异常情绪强度处理:来自事件相关电位的证据
Anpei Wei,Mengmeng Fan,Ting Liu et al.
Anpei Wei et al.
Background: Social cognitive impairment is a key vulnerability marker for psychosis and is commonly observed in individuals at clinical high risk (CHR). However, the neurophysiological mechanisms underlying abnormalities ...