High incidence of estrous cycle irregularities in heterogeneous stock (HS) rats is associated with footshock-resistant cocaine intake [0.03%]
不规则发情周期的大鼠种群与对电击具有cocaine抵抗性摄入有关
Elizabeth A Sneddon,Supakorn Chonwattanagul,Kathleen Bai et al.
Elizabeth A Sneddon et al.
Schaftoside inhibits neuroinflammation and exerts antidepressant effects through METTL3-mediated m6A modification of circ_0001470 sponging miR-183-5p to regulate MAP3K1 expression [0.03%]
Schaftoside通过METTL3介导的circ_0001470 mRNA N6-甲基腺苷（m6A）修饰海绵吸附miR-183-5p调节MAP3K1表达抑制神经炎症并产生抗抑郁作用
Haohao Wang,Jinxiang Wu,Keren Ma et al.
Haohao Wang et al.
Chronic semaglutide treatment enhances the incentive motivational value of a small food reward and associated cue in male and female rats [0.03%]
慢性塞马鲁肽治疗增强了雄性和雌性大鼠小型食物奖励及其相关线索的动机价值
Stephen E Chang,Christopher A Turner,Natalia Morales Pagán et al.
Stephen E Chang et al.
Xylazine exacerbates fentanyl-induced respiratory depression and prevents rescue by naloxone in mice [0.03%]
丁丙诺啡加重十字醉中安定和芬太尼引起的呼吸抑制且阻止纳洛酮解救作用在小鼠中的作用机制研究
Joshua M Watkins,Rachel Hahn,Michael Dempsey et al.
Joshua M Watkins et al.
Xylazine is a veterinary sedative and widespread adulterant of illicit opioids, where it is commonly detected in combination with the potent synthetic μ opioid receptor (MOR) agonist fentanyl in fatal overdose. We used whole body plethysmo...
Dual hypocretin receptor antagonists enhance sleep and nursing behavior in lactating rats [0.03%]
双重下丘脑分泌素受体拮抗剂可增强泌乳大鼠的睡眠和哺乳行为
Mayda Rivas,Florencia Peña,Clara Prota et al.
Mayda Rivas et al.
Rationale: Hypocretins (also known as orexins) are neuropeptides that regulate the sleep-wake cycle and modulate a variety of behaviors, including maternal behavior. They act through two receptor subtypes: hypocretin rece...
Integrated stress response inhibition rescues inflammation-associated accelerated forgetting of recognition memory in mice [0.03%]
整合应激反应抑制可缓解小鼠炎症相关识别记忆的加速遗忘现象
Shi-Yan Liu,Yi Zuo,Xin Jin et al.
Shi-Yan Liu et al.
D[His26]NPY, an agonist of NPY receptor 1, averts traumatic stress-induced behavioral deficits in male and female rats [0.03%]
D[His26]神经肽Y，一种神经肽Y受体1的激动剂，可缓解创伤性压力引起的雄性和雌性大鼠的行为障碍
Arax Tanelian,Bistra Nankova,Moshe Weiss et al.
Arax Tanelian et al.
The effects of reward uncertainty and alcohol intoxication on human sign- and goal-tracking [0.03%]
奖赏不确定性和酒精中毒对人类信号追踪和目标追踪的影响
Michelle Heck,Damien Lesenfants,Vincent Didone et al.
Michelle Heck et al.
Blood biomarker changes and relationships after low dose oral ketamine treatment for post-traumatic stress disorder (PTSD) [0.03%]
低剂量口服氯胺酮治疗后应激障碍(PTSD)的血液生物标志物变化及相互关系
Bonnie L Quigley,Emerald Orr,Sophie Kafka et al.
Bonnie L Quigley et al.
Decoding the molecular network communication mechanism of ketamine's antidepressant effects [0.03%]
解读氯胺酮抗抑郁作用的分子网络通讯机制
Ye Li,Qilong Cheng,Guoxin Lin et al.
Ye Li et al.