Long noncoding RNA UCA1 promotes the proliferation of hypoxic human pulmonary artery smooth muscle cells [0.03%]
长链非编码RNA UCA1促进低氧人肺动脉平滑肌细胞增殖
Tian-Tian Zhu,Rui-Li Sun,Ya-Ling Yin et al.
Tian-Tian Zhu et al.
Our study explored the effects of lncRNA UCA1 on the proliferation and apoptosis in hypoxic human pulmonary artery smooth muscle cells (HPASMCs) and highlighted the endogenous relationship between UCA1, ING5, and hnRNP I in cell proliferati...
Comparative electrophysiological analysis of the bile acid-sensitive ion channel (BASIC) from different species suggests similar physiological functions [0.03%]
来自不同物种的胆汁酸敏感离子通道(BASIC)的比较电生理分析表明其具有相似的生理功能
Pia Lenzig,Monika Wirtz,Dominik Wiemuth
Pia Lenzig
Despite the identification of cholangiocytes in the liver and unipolar brush cells in the cerebellum as sites of expression, the physiological function of the bile acid-sensitive ion channel (BASIC) remains unknown. Rat BASIC (rBASIC) and m...
Role of CINC-1 and CXCR2 receptors on LPS-induced fever in rats [0.03%]
CINC-1和CXCR2受体在内毒素诱导的大鼠发热中的作用研究
Lívia Harumi Yamashiro,Glória Emília Petto de Souza,Denis de Melo Soares
Lívia Harumi Yamashiro
The classic model of fever induction is based on the administration of lipopolysaccharide (LPS) from Gram-negative bacteria in experimental animals. LPS-induced fever results in the synthesis/release of many mediators that assemble an LPS-f...
Deception of cycling distance on pacing strategies, perceptual responses, and neural activity [0.03%]
骑行距离的欺骗对配速策略、感知反应和神经活动的影响
Georgia Wingfield,Frank E Marino,Melissa Skein
Georgia Wingfield
Pacing during exercise performance is well-established; however, little is known about the neural responses associated with changes in power output and the effect of exercise end-point knowledge. Therefore, the aim of this study was to exam...
The role of SLC34A2 in intestinal phosphate absorption and phosphate homeostasis [0.03%]
SLC34A2在肠吸收和磷稳态中的作用
Joanne Marks
Joanne Marks
There has recently been significant interest in the concept of directly targeting intestinal phosphate transport to control hyperphosphatemia in patients with chronic kidney disease. However, we do not have a complete understanding of the c...
Cora Weigert,Miriam Hoene,Peter Plomgaard
Cora Weigert
Regular physical activity not only improves the exercise capacity of the skeletal muscle performing the contractions, but it is beneficial for the whole body. An extensive search for "exercise factors" mediating these beneficial effects has...
Cardiomyopathy phenotypes in human-induced pluripotent stem cell-derived cardiomyocytes-a systematic review [0.03%]
人诱导多能干细胞源性心肌细胞中的心肌病表型-系统评价
Thomas Eschenhagen,Lucie Carrier
Thomas Eschenhagen
Human-induced pluripotent stem cells (hiPSC) can be differentiated to cardiomyocytes at high efficiency and are increasingly used to study cardiac disease in a human context. This review evaluated 38 studies on hypertrophic (HCM) and dilate...
Armin Kurtz
Armin Kurtz
Resveratrol long-term treatment differentiates INS-1E beta-cell towards improved glucose response and insulin secretion [0.03%]
白藜芦醇长期处理可改善INS-1E细胞的葡萄糖反应和胰岛素分泌功能
Marina Casimir,Gaelle Chaffard,Pierre Maechler
Marina Casimir
The clonal INS-1E beta-cell line has proven to be instrumental for numerous studies investigating the mechanisms of glucose-stimulated insulin secretion. The composition of its culture medium has not changed over the years, although some co...
Marc Francaux,Louise Deldicque
Marc Francaux
During the course of life, muscle mass undergoes many changes in terms of quantity and quality. Skeletal muscle is a dynamic tissue able to hypertrophy or atrophy according to growth, ageing, physical activity, nutrition and health state. T...