Evaluation of the relationship between intercostal muscle oxygenation measured by near-infrared spectroscopy and exercise capacity in group E COPD patients [0.03%]
评估NIRS测定的第E组慢性阻塞性肺疾病患者肋间肌氧合与运动能力之间的关系
Felipe Contreras-Briceño,Maximiliano Espinosa-Ramírez
Felipe Contreras-Briceño
Michael Eisenhut,Helen Wallace
Michael Eisenhut
Rhinorrhoea associated with viral upper respiratory tract infections or reactions to aeroallergens affects all human beings and has been associated with loss of quality of life. Pulmonary fluid accumulation in acute lung injury is a leading...
Role of ANO1 Ca2+-activated Cl- channels in the generation of propagating spontaneous Ca2+ transients of mouse bladder suburothelial pericytes [0.03%]
ANO1钙激活氯通道在小鼠膀胱黏膜下丛细胞自发性钙波释放中的作用
Ayu Sugiura,Retsu Mitsui,Kyoko Miwa-Nishimura et al.
Ayu Sugiura et al.
Pericytes in microvasculature of the bladder suburothelium develop spontaneous Ca2+ transients that propagate within the pericyte network. Here, the expression of ANO1 Ca2+-activated Cl- channels that serve as smooth muscle pacemaker channe...
Intravascular volume expansion is prominently overestimated via hemoglobin concentration: a placebo-controlled and cross-over trial [0.03%]
血红蛋白浓度显著高估了血管内容量:一项安慰剂对照及交叉试验
Meihan Guo,David Montero
Meihan Guo
Blood volume (BV) expansion by means of intravenous infusion of colloids is an established procedure in clinical interventions. The essential questions of how much of the infused fluid stays in the circulation according to measured changes ...
Energy metabolism in different skeletal muscles and muscle fibers: implications for injury and dietary supplementation [0.03%]
不同骨骼肌和肌纤维中的能量代谢:对损伤和饮食补充的影响
Andrey V Kuznetsov,Raimund Margreiter,Judith Hagenbuchner et al.
Andrey V Kuznetsov et al.
The necessary energy supply in skeletal muscles is based on either glycolysis or mitochondrial oxidative phosphorylation (OxPhos). These two bioenergetic pathways are in balanced complementation. Glycolysis is faster than OxPhos, whereas Ox...
Breaking the link between sarcoplasmic reticulum calcium leakage and mitochondria to counteract unloading-induced muscle atrophy [0.03%]
打破肌浆网钙离子泄漏与线粒体之间的联系以对抗失载诱导的肌肉萎缩
Carlo Reggiani,Lorenzo Marcucci
Carlo Reggiani
In muscle fibers, unloading and disuse cause an increase in resting calcium concentrations in the cytosol and mitochondrial matrix. S107, a stabilizer of the Ryanodine Receptor calcium channel (RyR), blocks the leakage from the sarcoplasmic...
Mitochondrial ATP synthase 8 single-nucleotide polymorphism affects oxidative stress and survival of mice [0.03%]
线粒体ATP合成酶8单核苷酸多态性影响小鼠的氧化应激和生存率
Gesine Reichart,Johannes Mayer,Tursonjan Tokay et al.
Gesine Reichart et al.
Single-nucleotide polymorphisms in mitochondrial DNA (mtDNA) encoded genes of respiratory chain complexes are known to be associated with severe diseases and life-threatening syndromes. In the assembly of the ATP synthase, the enzyme that i...
Professor Helmut Acker (1939-2025) : A Pioneer in Oxygen Sensing and Molecular Physiology [0.03%]
赫尔穆特·阿克教授(1939-2025):氧气感应和分子生理学的先驱
Till Acker,Joachim Fandrey,Jörgen Carlsson
Till Acker
Impact of combined exercise training in peripheral and diaphragm muscles and in mortality in a preclinical model of pulmonary arterial hypertension [0.03%]
联合运动训练对周围和膈肌肌肉及肺动脉高压临床前模型死亡率的影响
Thais C Freire,Antônio V Nascimento-Filho,Marília S Ferreira et al.
Thais C Freire et al.
Pulmonary arterial hypertension (PAH) is a progressive disease characterised by systemic oxidative stress and inflammation that extends beyond the pulmonary vasculature to the musculoskeletal system. Combined exercise training (ET), incorpo...
Effects of intrarenal afferent stimulation by bradykinin on renal sympathetic nerve activity: tonic inhibition contributing to renal function [0.03%]
缓激肽对肾交感神经活性的内肾传入刺激的影响:持续性抑制作用有利于肾脏功能
Eva Hutter,Tilmann Ditting,Martin Hindermann et al.
Eva Hutter et al.
Bradykinin (BK) may increase renal sodium excretion by decreasing tubular ENaC activity. Afferent renal nerve activity (ARNA) putatively controls renal sympathetic nerve activity (RSNA) involved in renal sodium handling. We recently found t...