Intracellular pH regulates the strength of the intrinsic inward rectification of Kir4.1/Kir5.1 channels [0.03%]
细胞内pH调节Kir4.1/Kir5.1通道内在整流强度
Iván A Aréchiga-Figueroa,Leticia G Marmolejo-Murillo,Mayra Delgado-Ramírez et al.
Iván A Aréchiga-Figueroa et al.
Kir4.1/Kir5.1 channels play a crucial role in important physiological functions, notably in the kidneys and brain. A hallmark of these channels is the coexistence of two mechanisms of inward rectification: the classical "extrinsic" inward r...
Intrinsic responses to hypoxia and hypercapnia of neurons in the cardiorespiratory center of the ventral medulla of newborn rats [0.03%]
新生大鼠延髓呼吸心血管中枢区神经元对低氧和高碳酸血症的内在反应
Hiroshi Onimaru,Yui Koyanagi,Kamon Iigaya et al.
Hiroshi Onimaru et al.
The rostral ventrolateral medulla (RVLM) includes a variety of neurons essential for cardiorespiratory control. Although some of these neurons are thought to be intrinsically sensitive to hypercapnia and/or hypoxia, relationships between ty...
Reproducibility of smooth muscle mechanical properties in consecutive stretch and activation protocols [0.03%]
连续拉伸和激活协议中平滑肌机械性能的可重复性
Simon Kiem,Stefan Papenkort,Mischa Borsdorf et al.
Simon Kiem et al.
Mechanical organ models are crucial for understanding organ function and clinical applications. These models rely on input data regarding smooth muscle properties, typically gathered from experiments involving stimulations at different musc...
Microbiota, mitochondria, and epigenetics in health and disease: converging pathways to solve the puzzle [0.03%]
健康与疾病的微生物群，线粒体和表观遗传学：解决谜题的汇聚途径
Natalia Lucia Rukavina Mikusic,Paula Denise Prince,Marcelo Roberto Choi et al.
Natalia Lucia Rukavina Mikusic et al.
Dysbiosis, which refers to an imbalance in the composition of the gut microbiome, has been associated with a range of metabolic disorders, including type 2 diabetes, obesity, and metabolic syndrome. Although the exact mechanisms connecting ...
Comprehensive overview of artificial intelligence in surgery: a systematic review and perspectives [0.03%]
手术中人工智能的综合概述：系统性回顾与展望
Olivia Chevalier,Gérard Dubey,Amine Benkabbou et al.
Olivia Chevalier et al.
The rapid integration of artificial intelligence (AI) into surgical practice necessitates a comprehensive evaluation of its applications, challenges, and physiological impact. This systematic review synthesizes current AI applications in su...
Neuronal subtype-dependent kinetics of EPSCs induced by thalamocortical projections from the ventroposteromedial thalamic nucleus to the insular cortex in rats [0.03%]
丘脑腹后内侧核到大脑岛叶皮层的投射在大鼠中诱导的EPSCs依赖于神经元亚型的出现动力学特性
Yuko Koyanagi,Kiyofumi Yamamoto,Kouhei Kitano et al.
Yuko Koyanagi et al.
Cerebrocortical neurons receive glutamatergic inputs via thalamocortical projections, and their activities are simultaneously controlled by GABAergic interneurons. Few studies have demonstrated the difference in the amplitude of evoked exci...
Special issue European Journal of Physiology: Artificial intelligence in the field of physiology and medicine [0.03%]
特刊 欧洲生理学杂志：人工智能在生理学和医学领域的应用
Anika Westphal,Ralf Mrowka
Anika Westphal
This special issue presents a collection of reviews on the recent advancements and applications of artificial intelligence (AI) in medicine and physiology. The topics covered include digital histopathology, generative AI, explainable AI (XA...
Obituary: Stefan Silbernagl - physiologist, gentleman, aesthete [0.03%]
讣告：Stefan Silbernagl - 生理学家，绅士，美学爱好者
Michael Gekle
Michael Gekle
Current methods in explainable artificial intelligence and future prospects for integrative physiology [0.03%]
可解释的人工智能的当前方法及综合生理学中的未来前景
Bettina Finzel
Bettina Finzel
Explainable artificial intelligence (XAI) is gaining importance in physiological research, where artificial intelligence is now used as an analytical and predictive tool for many medical research questions. The primary goal of XAI is to mak...
Emerging roles of PCSK9 in kidney disease: lipid metabolism, megalin regulation and proteinuria [0.03%]
PCSK9在肾脏疾病中扮演的新角色：脂质代谢、megalin调控和蛋白尿
Sandra Hummelgaard,Jean-Claude Kresse,Michael Schou Jensen et al.
Sandra Hummelgaard et al.
Chronic kidney disease (CKD) is a significant risk factor for cardiovascular disease (CVD). Key features of CKD include proteinuria and reduced glomerular filtration rate, both of which are linked to disease progression and adverse outcomes...