Beyond biological risk: socioeconomic vulnerability and adverse pediatric kidney transplant outcomes [0.03%]
超越生物学风险:社会经济脆弱性与儿科肾脏移植不良预后
Sarah Kizilbash,Chung-Ii Wi,Sandra Amaral et al.
Sarah Kizilbash et al.
Background: Adverse social determinants are known contributors to poorer long-term allograft outcomes. Yet optimal measures of social determinants are lacking. We sought to evaluate the association between socioeconomic s...
Evaluating construct validity of the PRO-Kid life participation tool for children living with chronic kidney disease [0.03%]
PRO-Kid生命参与工具的概念有效性的评估——慢性肾病儿童患者的参与体验
Karma Abukasm,Kimberley Widger,Adam Rapoport et al.
Karma Abukasm et al.
Background: Life participation is a priority outcome for children and families living with chronic kidney disease (CKD). This study aimed to assess the construct validity of the PRO-Kid-LP, a novel three-item tool measuri...
Clinical presentations, treatments, and outcomes of pediatric lupus nephritis: a prospective cohort study from the Pediatric Nephrology Research Consortium [0.03%]
儿童狼疮性肾炎的临床表现、治疗和转归:来自儿科肾脏病研究联盟的一篇前瞻性队列研究报告
Melonie Phillips,Mahmoud Kallash,Chloe Tang et al.
Melonie Phillips et al.
Background: There are few prospective studies of mycophenolate mofetil (MMF) versus cyclophosphamide (CYC) for pediatric lupus nephritis (pLN) and none evaluating rituximab (RTX). ...
Assessment of functional capacity in children with chronic kidney disease using various field tests [0.03%]
慢性肾脏病儿童功能状态的评测:不同场地测试方法的应用评估
Merve Firat,Aydan Asli Aksel-Uylar,Melda Saglam et al.
Merve Firat et al.
Background: Children with chronic kidney disease (CKD) often have a reduced functional capacity. The study aimed to evaluate the functional capacity of children with CKD by using three field tests: 6 min walk (6MWT), 2 mi...
Dual pathogenic variants in ADAMTS13 and CFHR1/CFHR3 deletion: divergent thrombotic microangiopathy phenotypes in siblings [0.03%]
ADAMTS13和CFHR1/CFHR3基因缺失的双致病突变:兄弟姐妹中不同的血栓性微血管病表型
Mona Hamed Gehad,Doaa M Youssef,Amal S El-Shal et al.
Mona Hamed Gehad et al.
Two male siblings, aged 15 and 13 years, born to consanguineous parents, presented with hereditary anemia and thrombocytopenia associated with unexplained hepatosplenomegaly. Both were initially diagnosed with hereditary cytopenia and maint...
Urinary podocalyxin identifies a pre-albuminuric kidney injury window and stratifies 12-year diabetic kidney disease risk in youth with type 1 diabetes mellitus [0.03%]
尿液podocalyxin可识别糖尿病肾病前期损伤阶段并可用于分层1型糖尿病青少年患者的12年发病风险
Seniha Kiremitci Yilmaz,Betul Ersoy,Nilay Tuğçe Işık Bayar et al.
Seniha Kiremitci Yilmaz et al.
Background: Microalbuminuria indices may miss early diabetic kidney disease (DKD) and can regress. Urinary podocyte and tubular injury biomarkers may detect subclinical kidney injury before albuminuria. We evaluated urina...
Systemic lupus erythematosus with lupus nephritis in a child with chronic granulomatous disease: a diagnostic and therapeutic challenge [0.03%]
慢性肉芽肿病患儿并发系统性红斑狼疮和狼疮肾炎的诊断与治疗挑战
Elisa Profeti,Stefania Ferradino,Dario Francesco DUrso et al.
Elisa Profeti et al.
Chronic granulomatous disease (CGD) is an inborn error of immunity (IEI) characterized by defective NADPH oxidase activity, leading to severe infections, hyperinflammation, and immune dysregulation. Autoimmune manifestations are increasingl...
Trends in chronic dialysis practices and outcomes in North American children: a 30-year NAPRTCS registry analysis [0.03%]
北美儿童慢性血液透析的现状和结局——来自NAPRTCS注册中心的一项为期30年的分析研究报告
Ankana Daga,Kathleen Altemose,Sarah Twichell et al.
Ankana Daga et al.
Background: The North American Pediatric Renal Trials and Collaborative Studies (NAPRTCS) registry has tracked outcomes of children receiving maintenance dialysis since 1992. ...
A systematic review of short-term outcomes in patients with anti-factor H associated atypical HUS managed with plasma exchanges versus eculizumab [0.03%]
补体抑制剂与血浆置换治疗抗因子H相关非典型溶血性尿毒症的疗效系统评价研究
Aditi Sinha,Tanvi Bindal,Federica Zotta et al.
Aditi Sinha et al.
Background: Antibodies to factor H (anti-FH) are a leading cause of atypical hemolytic uremic syndrome (aHUS) in school-going children. While terminal complement blockade with eculizumab (ECZ) is standard of care for all ...
Bile acid metabolites and carotid intima media thickness in the Chronic Kidney Disease in Children (CKiD) study [0.03%]
儿童慢性肾脏病研究中胆酸代谢产物与颈动脉内膜中层厚度的关系
Arthur M Lee,Mark M Mitsnefes,Jennifer Roem et al.
Arthur M Lee et al.