AFAP1-AS1 regulates oral squamous cell carcinoma development through the miR-93-3p/CCND1 signaling pathway [0.03%]
AFAP1-AS1通过miR-93-3p/CCND1信号通路调节口腔鳞状细胞癌的发生发展
Kuangzheng Li,Chengwei Li,Qian He et al.
Kuangzheng Li et al.
Actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1) has been found to be closely associated with the initiation and progression of various tumors; however, its role in oral squamous cell carcinoma (OSCC) remains unclear. AFAP1-A...
Genome-wide association study of mature cow size traits in American Angus cattle [0.03%]
美国安格斯牛成熟母牛体尺性状的全基因组关联分析
Ayooluwa O Ojo,Henrique A Mulim,Milena A F Campos et al.
Ayooluwa O Ojo et al.
Mature cow weight (MWT), height (MHT), and body condition score (BCS) are economically important traits that significantly influence cowherd profitability by affecting maintenance feed requirements, which is the largest component of product...
Mapping genomic adaptation to environmental heterogeneity in Indian native goat populations through landscape genomics [0.03%]
印度土种山羊种群基因组适应环境异质性的全景基因组学研究
Pallavi Rathi,Nidhi Sukhija,Indrajit Ganguly et al.
Pallavi Rathi et al.
India harbours a diverse range of indigenous goat breeds that have adapted to varied climatic zones over centuries. This study investigated the genomic basis of local adaptation in these populations (n= 11) divided into seven agro-climatic ...
Primary biliary cirrhosis and rheumatoid arthritis: a comprehensive study combining genetics and transcriptomics [0.03%]
原发性胆汁性肝硬化和类风湿关节炎：结合遗传学和转录组学的综合研究
Mingyi Yang,Honghao Ren,Xiaodong Ren et al.
Mingyi Yang et al.
Observational investigations have discerned a correlation between primary biliary cirrhosis (PBC) and rheumatoid arthritis (RA). The primary objective of this study is to elucidate the disease risk correlation between them in terms of genet...
Genome-wide characterization of HSP70 and HSP90 subfamilies in Yak (Bos grunniens): expression patterns under cold and chemical hypoxia conditions [0.03%]
牦牛(HIS70和HSP90亚家族的全基因组特征鉴定：在寒冷及化学缺氧条件下的表达模式
Yufei Zan,Caiwei Ma,Ziqiang Ding et al.
Yufei Zan et al.
Assessment of genome-wide genetic variability and population divergence of four native Turkish sheep breeds [0.03%]
四种土库曼本地绵羊品种的全基因组遗传变异和种群分化评估
Bahar Argun Karslı,Eymen Demir,Umit Bilginer et al.
Bahar Argun Karslı et al.
Genetic variability is crucial for enhancing economically important traits and for developing effective conservation strategies in livestock populations. In this study, genome-wide genetic variability and population divergence were evaluate...
Integrative immunogenomic and experimental characterization reveals CXCL9, CXCL13, CCL5 and CD74 as key oncogenic drivers in breast cancer [0.03%]
整合的免疫基因组和实验分析揭示了CXCL9、CXCL13、CCL5和CD74是乳腺癌中的关键致癌驱动因素
Mohammed A Alshehri,Mohammed Alissa
Mohammed A Alshehri
Breast cancer remains the most prevalent malignancy among women worldwide, driven by complex interactions between tumor-intrinsic factors and the immune microenvironment. Understanding immune-related molecular regulators is essential to imp...
Tissue-specific transcriptional epistasis between Prkn and Lrrk2 during mycobacterial infection [0.03%]
帕金森病相关基因Prkn和Lrrk2在结核分枝杆菌感染下的组织特异性转录上位性作用机制研究
Monica Dallmann-Sauer,Yong Zhong Xu,Wilian Correa-Macedo et al.
Monica Dallmann-Sauer et al.
Unravelling male infertility through epigenetics: present understanding and future challenges [0.03%]
从表观遗传学视角解读男性不育：现状与挑战
S Amrita Malini,Almitra Abhijit Dravid,Ritwika Saha et al.
S Amrita Malini et al.
Hongwu mixture exerts inhibition on triple-negative breast cancer by regulating SAV1/Hippo signaling through ZNF143 [0.03%]
通过ZNF143调节SAV1/Hippo信号对三阴性乳腺癌的洪朴药方混合物作用研究
Aiping Wu,Jun Ma,Qiong Wang et al.
Aiping Wu et al.
Hongwu mixture (HWM) consists of Taxus chinensis, Marsdenia tenacissima, Rhizoma Curcumae, and Semen coicis. The objective of this study was to ascertain the potential role of the Hongwu mixture (HWM) in the treatment of triple-negative bre...