Alberto Arturo Vergani
Alberto Arturo Vergani
Locus coeruleus neuromelanin, cognitive dysfunction, and brain metabolism in multiple system atrophy [0.03%]
蓝斑黑素体、认知障碍和多系统萎缩患者的脑代谢关系
Jacopo Pasquini,Hilmar P Sigurdsson,Michael Firbank et al.
Jacopo Pasquini et al.
Background: Cognitive dysfunction is increasingly recognized in multiple system atrophy (MSA). Locus coeruleus (LC) integrity is associated with cognitive performance both in healthy controls (HC) and neurodegenerative co...
Isolated CSF RT-QuIC positivity associates with a less aggressive disease course and decreased levels of neuronal/glial damage biomarkers in patients with sporadic Creutzfeldt-Jakob disease [0.03%]
脑脊液RT-QUIC阳性与散发性克雅病患者的较温和疾病过程及神经元/星形胶质细胞损伤生物标志物水平降低相关
Laura Naranjo,Jordi Sarto,Carlos Nos et al.
Laura Naranjo et al.
Discrepancies in results between cerebrospinal fluid (CSF) 14-3-3 protein and prion protein detection using real-time quaking-induced conversion (RT-QuIC) might limit the confidence in ante-mortem clinical diagnosis of sporadic Creutzfeldt-...
Multicenter Study
Journal of neurology. 2025 Feb 11;272(3):198. DOI:10.1007/s00415-024-12757-8 2025
Orthostatic hypotension is involved in cognitive impairment in patients with multiple system atrophy: a multi-center cohort study in China [0.03%]
中国多中心队列研究发现姿势性低血压参与了多系统萎缩的认知障碍病理过程
Wanlin Li,Yan Ding,Zhenbo Zhao et al.
Wanlin Li et al.
Background: Orthostatic hypotension (OH) is a common symptom of multiple system atrophy (MSA), however, its role in cognitive impairment and the mechanism in these patients remains unclear. This study aims to assess the r...
Observational Study
Journal of neurology. 2025 Feb 11;272(3):186. DOI:10.1007/s00415-025-12936-1 2025
Outcome measurement in functional neurological disorder: A qualitative study on the views of patients, caregivers and healthcare professionals [0.03%]
功能性神经障碍的结局评估指标：患者、照料者和医护人员的观点分析研究
Sonja Rutten,Abigail Bradley-Westguard,Timothy R Nicholson et al.
Sonja Rutten et al.
Background: In this qualitative study, we aimed to obtain and synthesise the views of patients with functional neurological disorder (FND), their caregivers, and relevant healthcare professionals (HCPs) on outcome measure...
Persistent geotropic or apogeotropic nystagmus: recurrence and association with vestibular migraine [0.03%]
持续性地心引力性或离心引力性眼球震颤：复发及与前庭型偏头痛的关系
Tzu-Pu Chang,Ying-Chi Hong,Yu-Hung Kuo et al.
Tzu-Pu Chang et al.
Background: The underlying etiologies responsible for persistent geotropic nystagmus (PGN) and apogeotropic nystagmus (PAGN) remain elusive. In this study, we analyzed the symptoms of patients with PGN and PAGN and catego...
SOD1-related inherited peripheral neuropathies in a Japanese cohort: genetic variants and clinical insights [0.03%]
在日本队列中与SOD1相关的遗传性周围神经病的基因变异及临床特征研究
Masahiro Ando,Yujiro Higuchi,Jun-Hui Yuan et al.
Masahiro Ando et al.
Background: Inherited peripheral neuropathies (IPNs) encompass a wide range of disorders affecting the peripheral nervous system, often with complex genetic causes and frequent underdiagnosis. The variants in the superoxi...
A real-world study on the utility of regular rituximab treatment for neuromyelitis optica spectrum disorder [0.03%]
NMOSD患者利妥昔单抗维持治疗的疗效和安全性的真实世界研究
Xuefen Chen,Rui Wang,Rui Li et al.
Xuefen Chen et al.
Rituximab (RTX) is a monoclonal antibody targeting the B-cell CD20 surface antigen used as a prophylactic treatment for Aquaporin 4-immunoglobulin G (AQP4-IgG)-positive neuromyelitis optica spectrum disorder (NMOSD). However, a consensus re...
Portable ultra-low-field MRI for progressive multifocal leukoencephalopathy: Case studies, sensitivity, and potential applications [0.03%]
便携式极低场磁共振在多灶性白质脑病中的应用：病例研究、敏感性和潜在应用能力
Serhat V Okar,Karan D Kawatra,Ashley A Thommana et al.
Serhat V Okar et al.
Background and objective: Progressive multifocal leukoencephalopathy (PML) is a severe, disabling infection caused by JC virus reactivation. PML-related disability complicates the MRI monitoring needed to assess treatment...
Differences in functional outcome of COVID-19 and non-COVID-19 patients with critical illness polyneuropathy/ myopathy: a multicenter cohort study [0.03%]
一项多中心队列研究：比较新冠肺炎与非新冠肺炎患者重症神经肌肉病变的功能预后差异
Michael Klein,Bernadette Einhäupl,Eva Grill et al.
Michael Klein et al.
Background: Up to 80% of intensive care unit (ICU) patients suffer from neuromuscular disorders like critical illness polyneuropathy/myopathy (CIP/CIM), requiring further rehabilitation. ...
Observational Study
Journal of neurology. 2025 Feb 11;272(3):197. DOI:10.1007/s00415-024-12873-5 2025