Clinical-functional dissociation in bilateral vestibulopathy: determinants of disability beyond peripheral vestibular loss [0.03%]
双侧前庭病的临床-功能分离：外周前庭丧失之外影响残疾性的决定因素
Joan Lorente-Piera,Ángel Ramos de Miguel,Raquel Manrique-Huarte et al.
Joan Lorente-Piera et al.
Background: Bilateral vestibulopathy (BVP) is characterized by bilateral vestibular hypofunction and classically manifests with oscillopsia and postural instability. However, clinical severity is highly heterogeneous and ...
Multicenter Study
Journal of neurology. 2026 Aug 2;273(8):500. DOI:10.1007/s00415-026-14019-1 2026
João Pedro do Couto Caetano,Juliana da Rosa Perez,Noéli Boscato
João Pedro do Couto Caetano
Carlos Estevez-Fraga,Rodrigo Alvarez-Velasco,Tariq Afroz et al.
Carlos Estevez-Fraga et al.
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive neurodegenerative disorder characterized by motor neuron degeneration leading to early mortality. Despite advances in understanding genetic and molecular contributors, effective d...
Central nervous system histopathological findings in classic infantile Pompe disease: a systematic review with clinical relevance [0.03%]
经典婴儿型庞贝病中枢神经系统组织病理特征的系统性回顾及其临床意义
Jan J A van den Dorpel,Martha C Faraguna,Robert M Verdijk et al.
Jan J A van den Dorpel et al.
Introduction: Classic infantile Pompe disease is the most severe phenotype within the clinical spectrum of Pompe disease and is characterized by central nervous system (CNS) involvement. ...
Estimating the minimal clinically important difference of functional outcomes in spinal and bulbar muscular atrophy [0.03%]
估算脊髓和球麻痹功能结果的最小临床重要差异性
Matteo Zanovello,Daniele Sabbatini,Federica Paredi et al.
Matteo Zanovello et al.
Background and objectives: Spinal and bulbar muscular atrophy (SBMA) is a slowly progressive X-linked neuromuscular disorder for which disease-modifying therapies are under investigation. SBMA Functional Rating Scale (SBM...
Prognostic factors in paediatric-onset multiple sclerosis: a narrative review [0.03%]
儿童期发病多发性硬化的预后因素：综述文章
Mariaclara Achille,Massimiliano Copetti,Tommaso Guerra et al.
Mariaclara Achille et al.
Background: Paediatric-onset multiple sclerosis (POMS) accounts for 3-10% of multiple sclerosis (MS) cases and differs from adult-onset disease in course, treatment response and long-term outcomes. Risk stratification is ...
Spatial analysis of paraneoplastic cerebellar degeneration in ovarian cancer with anti-Yo syndrome and SCA1 [0.03%]
卵巢癌抗Yo综合征并脊髓小脑共济失调1型患者副肿瘤性小脑变性的空间分布分析
Tamara Künzle,Lucas Rincon de la Rosa,Clément Vialatte de Pémille et al.
Tamara Künzle et al.
Background: Anti-Yo paraneoplastic cerebellar degeneration (PCD) is a rare autoimmune disorder linked to ovarian and breast cancers. Neurological symptoms often precede cancer diagnosis, yet conventional imaging technique...
Plasma cardiac troponin T complements neurofilament light chain by reflecting disease phase and phenotypic variation in amyotrophic lateral sclerosis [0.03%]
血浆心肌肌钙蛋白T补充神经丝轻链反映疾病阶段和肌萎缩侧索硬化表型变异
Julia Sellin,Linn Öijerstedt,Janina von der Gablentz et al.
Julia Sellin et al.
Background: Neurofilament light chain (NfL) is an established marker of neuronal injury and disease aggressiveness in amyotrophic lateral sclerosis (ALS). In contrast, the clinical and biological significance of cardiac t...
Clinical outcomes at 6 months after MRgFUS thalamotomy in Parkinson's disease: a large longitudinal cohort study [0.03%]
一项关于帕金森病的大规模纵向队列研究的临床结果：MRgFUS丘脑毁损术后6个月的情况
Francesca Pistoia,Federico Salfi,Francesco Arrigoni et al.
Francesca Pistoia et al.
Background: Magnetic resonance-guided focused ultrasound (MRgFUS) is an expanding therapy for tremor in Parkinson's disease (PD). This study aimed to characterize trajectories of tremor and cognitive functions following M...
Observational Study
Journal of neurology. 2026 Jul 26;273(8):492. DOI:10.1007/s00415-026-14021-7 2026
Right hemisphere involvement in intensive aphasia therapy outcomes: a multimodal neuroimaging concept study [0.03%]
右半球参与密集型失语症治疗效果的多模态神经影像概念研究
Nina Scholtes,Stefan Heim,Ferdinand Binkofski et al.
Nina Scholtes et al.
Background: Few studies investigated factors that predict intensive language therapy (ILT) outcome. This study aimed to analyze multimodal neural factors that possibly underly ILT success. ...