Sabbiha Nadia Majumder,Marc Edwards,Robin Corkill
Sabbiha Nadia Majumder
Biological frameworks for Parkinson's disease: the heterogeneity SAAgged [0.03%]
帕金森病的生物学框架:SAAggregated异质性
Annamaria Landolfi,Cristiano Sorrentino,Paolo Barone et al.
Annamaria Landolfi et al.
Recent biological frameworks of Parkinson's disease (PD) rely on the new advances in α-synuclein detection in biological tissues, mostly through α-synuclein seed amplification assays, and are mainly aimed at intercepting pre-clinical or e...
Limited added value of systematic spinal cord MRI vs brain MRI alone to classify patients with MS as active or inactive during follow-up [0.03%]
在随访期间，系统性脊髓磁共振成像较脑部磁共振成像对MS患者进行分类的价值有限
Jérémy Hong,Malo Gaubert,Mathilde Lefort et al.
Jérémy Hong et al.
Background: The utility of systematic spinal cord (SC) MRI for monitoring disease activity after a multiple sclerosis (MS) diagnosis remains a topic of debate. ...
Comparative Study
Journal of neurology. 2025 Apr 5;272(4):316. DOI:10.1007/s00415-025-13068-2 2025
Recall vaccination increases detectable B-cell reactivity in persons with multiple sclerosis treated with ocrelizumab [0.03%]
加强免疫接种可增加奥瑞珠单抗治疗的多发性硬化症患者体内B细胞反应性
Lucia Moiola,Alessandra Mandelli,Maciej Tarkowski et al.
Lucia Moiola et al.
Background: Utility of repeated boosts of anti-SARS-CoV-2 vaccination in persons with MS (pwMS) treated with ocrelizumab is questioned. Objective: ...
Rate of change in upper and lower motor neuron burden is associated with survival in amyotrophic lateral sclerosis [0.03%]
渐冻症患者的上下运动神经元负担变化率与生存期相关性研究
A Maranzano,F Gentile,M Passaretti et al.
A Maranzano et al.
Background: We hypothesize that the rate of change in upper (ΔUMN) and lower (ΔLMN) motor neuron signs from symptom onset to first clinical assessment represent best predictors of survival and disease progression in amy...
Delayed neurological recovery in ischemic stroke patients undergoing endovascular treatment is associated with baseline hyperglycemia: a treatable cause of the stunned brain phenomenon? [0.03%]
缺血性卒中患者接受血管内治疗后延迟神经功能恢复与基线高血糖相关：脑“休克”现象的一个可治疗原因？
Susan Klapproth,Lukas Meyer,Helge Kniep et al.
Susan Klapproth et al.
Background and aims: In ischemic stroke, there is limited data regarding the impact of baseline hyperglycemia on the treatment effect of recanalization on neurological recovery. This study aimed to directly compare-how sh...
Observational Study
Journal of neurology. 2025 Apr 4;272(4):313. DOI:10.1007/s00415-025-13019-x 2025
Cerebrospinal fluid and blood neurofilament light chain in Parkinson's disease and atypical parkinsonian syndromes: a systematic review and Bayesian network meta-analysis [0.03%]
帕金森病和非典型帕金森综合征的脑脊液和血液神经丝轻链：系统评价与贝叶斯网状Meta分析
Wenyi Kou,Siming Li,Rui Yan et al.
Wenyi Kou et al.
Background and objective: The value of neurofilament light chain (NfL) levels as a biomarker for the diagnosis and differential diagnosis in patients with Parkinson's disease (PD) and atypical parkinsonian syndromes (APS)...
Does deep brain stimulation of the anterior nucleus of the thalamus represent the future of Lennox-Gastaut syndrome? [0.03%]
扣带回前核的深部脑刺激会是Lennox Gastaut综合征的治疗前景吗？
Gaëtan Poulen,Philippe Gélisse,Arielle Crespel et al.
Gaëtan Poulen et al.
Background: Some studies have indicated that deep brain stimulation (DBS) of the thalamus targeting the centromedian nucleus (CMN) may reduce the frequency of seizures in Lennox-Gastaut syndrome (LGS), albeit with incompl...
Clinical benefits of invasive intracranial pressure monitoring for spontaneous intracranial hemorrhage: a systematic review and meta-analysis [0.03%]
自发性颅内出血患者有创颅内压监测临床获益的系统评价和meta分析
Dan Shen,Lailai Shen,Xinjian Du et al.
Dan Shen et al.
Background: This meta-analysis evaluated the clinical benefits of invasive intracranial pressure (ICP) monitoring for spontaneous intracranial hemorrhage with specific focuses on the hypertensive intracerebral hemorrhage ...
Procedural and Clinical Outcome of Stroke after thrombectomy according to etiology: results from a nationwide registry [0.03%]
根据病因的机械取栓术后患者治疗及临床结局：一项全国性登记研究的结果分析
Ilaria Casetta,Giovanni Pracucci,Valentina Saia et al.
Ilaria Casetta et al.
Background: The impact of stroke etiology on outcomes in patients who underwent endovascular thrombectomy (EVT) is still a matter of debate. We studied the effect of aterosclerotic versus cardioembolic etiology on the cli...
Observational Study
Journal of neurology. 2025 Apr 2;272(4):308. DOI:10.1007/s00415-025-13026-y 2025