Long-term persistence, safety and effectiveness of nusinersen in spinal muscular atrophy: a population-based study [0.03%]
长期追访氯瑞森用于脊髓性肌萎缩的疗效和安全性：基于人群的研究
Karolina Aragon-Gawinska,Nancy Carolina Nungo-Garzon,Nuria Muelas et al.
Karolina Aragon-Gawinska et al.
Background and objective: Nusinersen was the first disease-modifying treatment approved for spinal muscular atrophy (SMA). However, long-term results of broad unselected populations-particularly adolescents and adults-rem...
Observational Study
Journal of neurology. 2026 Jun 29;273(7):430. DOI:10.1007/s00415-026-13965-0 2026
Quantification of amyotrophic lateral sclerosis (ALS) disease accumulation with T1-weighted high-resolution magnetic resonance imaging: validation in an independent cohort [0.03%]
使用T1加权高分辨率磁共振成像量化肌萎缩侧索硬化症（ALS）疾病累积：在独立队列中的验证研究
Philip Alexander Gremmler,Janina von der Gablentz,Julia Meyer et al.
Philip Alexander Gremmler et al.
Background: Amyotrophic Lateral Sclerosis (ALS) is a progressive neuromuscular disease with multifaceted phenotypic presentation thus obstructing objective disease staging. The D50 disease progression model is a framework...
Neuropsychological impairments in emotion recognition compared to general cognition: profiles across six different neurological disorders [0.03%]
六种神经精神疾病患者情绪识别与整体认知功能损害的差异及各疾病的认知亚型特征
Amber Heegers,Sandra E Rakers,Marieke E Timmerman et al.
Amber Heegers et al.
Objective: Social cognition, particularly emotion recognition, can be impaired in neurological disorders involving brain damage and neurocognitive deficits. However, it remains unclear whether distinctive profiles of soci...
The clinical, radiological and genetic spectrum AARS2-related leukoencephalopathy: a case series of 15 patients and review of the literature [0.03%]
AARS2相关性脑白质病的临床、影像及基因特点：15例报道和文献复习
Charles Wade,Anderson Rodrigues Brandão de Paiva,Paulo Ribeiro Nóbrega et al.
Charles Wade et al.
Background: AARS2-related leukoencephalopathy is a rare autosomal recessive leukodystrophy with overlapping clinical and radiological features with CSF1R-related disease but distinct genetic and phenotypic characteristics...
Marcello Cherchi
Marcello Cherchi
See-saw nystagmus (SSN), and the possibly related hemi-see-saw nystagmus (hSSN), occur in certain forms of visual loss and in some brainstem lesions. These disparate lesions have made it challenging for investigators to arrive at a unified ...
The relationship between cerebellar functional connectivity alterations and hand dexterity impairment in multiple sclerosis [0.03%]
多发性硬化患者小脑功能连接改变与手灵巧度损伤的关系研究
Emma Gangemi,Claudia Piervincenzi,Silvia Tommasin et al.
Emma Gangemi et al.
Background and purpose: Altered cerebellar resting-state functional connectivity (FC) may contribute to hand motor impairment in People with Multiple Sclerosis (PwMS). We aimed to assess whether: 1. FC abnormalities of th...
Plasma p-tau217 best captures early longitudinal cognitive changes in subjective cognitive decline compared with p-tau181 and NfL [0.03%]
与p-tau181和NfL相比，血浆p-tau217最能捕捉主观认知下降的早期纵向认知变化
Giulia Giacomucci,Alice Pieri,Silvia Bagnoli et al.
Giulia Giacomucci et al.
Background: Blood-based biomarkers are increasingly used to support the biological diagnosis of Alzheimer's disease (AD), but their prognostic value in subjective cognitive decline (SCD) remains incompletely understood. W...
Health-related quality of life outcomes with nipocalimab versus placebo in generalized myasthenia gravis: an analysis of the Vivacity-MG3 study [0.03%]
尼波卡利单抗与安慰剂治疗全身型重症肌无力的健康相关生活质量结局：Vivacity-MG3 研究分析结果
John Vissing,Sheryl Pease,Kayla Scippa et al.
John Vissing et al.
Background: Generalized myasthenia gravis (gMG) is an autoimmune disorder that is marked by fluctuating muscle weakness and poor health-related quality of life (HRQoL). This pre-specified analysis of the phase 3 Vivacity-...
Clinical Trial
Journal of neurology. 2026 Jun 26;273(7):423. DOI:10.1007/s00415-026-13978-9 2026
Social anxiety as a trigger for freezing of gait in Parkinson's disease: a case report [0.03%]
帕金森病冻结步态的社会焦虑触发因素：个案报告
Gijs Vissers,William R Young,Jorik Nonnekes
Gijs Vissers
Long-term outcomes after non-aneurysmal, non-traumatic subarachnoid hemorrhage: a prospective multicenter outcome study [0.03%]
非动脉瘤性、非创伤性的蛛网膜下腔出血的长期预后：一项前瞻性多中心结局研究
Wouter J Dronkers,Femke Geelen,Alyson Gross et al.
Wouter J Dronkers et al.
Objective: Non-aneurysmal, non-traumatic subarachnoid hemorrhage (nSAH) refers to cases where a causative aneurysm cannot be identified. Stratification into perimesencephalic non-aneurysmal SAH (PMSAH) and non-perimesence...
Multicenter Study
Journal of neurology. 2026 Jun 25;273(7):420. DOI:10.1007/s00415-026-13939-2 2026