Efficacy and safety of monoclonal antibodies in the treatment of relapsing remitting multiple sclerosis: a systematic review [0.03%]
治疗复发缓解型多发性硬化症的单克隆抗体疗效和安全性的系统综述
Ana Avedillo-Salas,Laura Baeza Martínez,Ana Fanlo-Villacampa et al.
Ana Avedillo-Salas et al.
Introduction: In relapsing-remitting multiple sclerosis (RRMS), conventional immunomodulatory and immunosuppressive therapies are widely used. However, in many cases, optimal control of inflammatory activity and disease p...
Longitudinal trajectories of apathy in Huntington's disease: a 6-year follow-up study [0.03%]
亨廷顿舞蹈病冷漠的纵向轨迹：一项为期六年的随访研究
Emilie Poulsen,Rebecca K Hendel,Birna Ásbjörnsdóttir et al.
Emilie Poulsen et al.
Objective: Apathy is a common and debilitating neuropsychiatric symptom in Huntington's disease (HD), yet its long-term trajectory remains poorly characterized. This study examined changes in apathy in HD gene expansion c...
Acute vertigo and dizziness: the diagnostic potential of static posturography in the neurological emergency department [0.03%]
急性眩晕和头晕：神经科急诊平衡功能检查的诊断价值
Laurin Schappe,HeimigEmily Heimig,Daniel Janitschke et al.
Laurin Schappe et al.
Background: Vertigo and dizziness are common in the emergency room, caused by a broad spectrum of conditions ranging from life-threatening to non-organic causes such as functional dizziness. The latter is often underdiagn...
Alzheimer's disease: disrupted communication between the endoplasmic reticulum and mitochondria [0.03%]
阿尔茨海默病：内质网和线粒体之间通信中断
Jiafu Guo,Ziying Yang,Shiyan Luo et al.
Jiafu Guo et al.
Alzheimer's disease (AD) remains a major, intractable neurodegenerative disorder and a serious threat to human health, characterized by a protracted clinical course, gradual progression, and irreversible cognitive decline. The current thera...
Optic chiasmal neuritis: clinical features, aetiologies, MRI patterns and prognosis in a real-world cohort [0.03%]
视交叉神经炎的临床特征、病因、MRI表现和预后：真实世界队列研究
Vincent Brochard,Augustin Lecler,Edouard Januel et al.
Vincent Brochard et al.
Background: Optic chiasmal neuritis (OCN) is considered atypical for multiple sclerosis (MS) and more frequently associated with neuromyelitis optica spectrum disorders (NMOSD). Yet the true aetiological spectrum of OCN i...
Predicting disease progression in multiple sclerosis with clinically accessible information and technology [0.03%]
基于临床可用信息和技术预测多发性硬化病的进展
Tom A N Fuchs,Menno M Schoonheim,Eva M M Strijbis et al.
Tom A N Fuchs et al.
Background: Predicting disease progression at the individual level is essential for personalized medicine. We previously developed machine-learning tools to estimate 5-year progression risk in people with multiple scleros...
Multicenter Study
Journal of neurology. 2026 Apr 19;273(5):281. DOI:10.1007/s00415-026-13802-4 2026
The association of night shift work with the risk of acute ischemic cerebrovascular syndrome: a longitudinal study of 204,261 UK Biobank participants [0.03%]
关于夜班工作与急性脑梗相关风险的纵向研究：英国生物银行204261名参与者的数据分析
Yanhao Huang,Min-Hui Tan,Guanghui Wang et al.
Yanhao Huang et al.
Background: Shift work is highly prevalent globally, yet evidence linking it to ischemic cerebrovascular disease remains inconsistent. Existing studies are limited by unsystematic quantification of night shift exposure an...
David Croteau,Anne Tobenkin,Vicky Chan et al.
David Croteau et al.
Background and objectives: To characterize a large case series of corneal edema associated with amantadine and to disseminate the information on that safety risk. ...
Correlations between peripheral neuropathy profiles and vascular skin lesions [0.03%]
外周神经病变与血管性皮肤病变的相关性研究
Morgan Dornadic,Didier Bessis,Florence Esselin et al.
Morgan Dornadic et al.
Background: Peripheral neuropathies may present with vascular skin lesions, such as livedo racemosa, ulcers, palpable purpura, or necrosis. These rare neurocutaneous associations can be severe and life-threatening. ...
Enhanced antibody detection via live cell-based assay among RIA negative myasthenia gravis patients: toward improved diagnosis and clinical correlates [0.03%]
针对RIA阴性重症肌无力患者的活细胞增强型抗体检测：改善诊断和临床相关性
Elena Rinaldi,Elisa Puleo,Angela Di Maro et al.
Elena Rinaldi et al.
Background: Radioimmunoprecipitation assay (RIA) is the gold standard for antibody detection in myasthenia gravis (MG), while fixed cell-based assays (CBAs) are widely used as second-line or first-line tests. Live CBA rep...