Annual level changes of serum neuronal and glial biomarkers in a German professional football club [0.03%]
德国一家职业足球俱乐部的血清神经元和胶质生物标志物年度变化水平
Robert Marshall,Samir Abu-Rumeileh,Lisa Habeck et al.
Robert Marshall et al.
Background: Professional football players (PFP) experience repeated mild traumatic brain injuries (TBI) and have an increased long-term dementia risk. We aimed to assess annual level changes of blood neuronal (neurofilame...
Nisa Vorasoot,Cigdem Isitan-Alkawadri,Bharat Pillai et al.
Nisa Vorasoot et al.
Complement activation profiles in patients with immune checkpoint inhibitor-associated neuromuscular immune-related adverse events [0.03%]
免疫检查点抑制剂相关神经肌肉型免疫相关不良事件患者的补体激活模式
Leonie Müller-Jensen,Nora Möhn,Thomas Skripuletz et al.
Leonie Müller-Jensen et al.
Background: Immune-related neuropathy (irNeuropathy) and myositis (irMyositis) are the most common neurologic adverse events (irAE-n) associated with immune checkpoint inhibitors. Although case reports suggest benefits of...
Multicenter Study
Journal of neurology. 2025 Jun 12;272(7):459. DOI:10.1007/s00415-025-13181-2 2025
Prospective quantitative evaluation of gait and stance in patients with acute vertigo and dizziness [0.03%]
急性眩晕和头晕患者的步态和站立姿势的定量评估
Hristo Hadzhikolev,Ken Möhwald,Patricia Jaufenthaler et al.
Hristo Hadzhikolev et al.
Background: Patients with acute vertigo and dizziness often suffer from gait ataxia and postural imbalance. However, detailed and quantitative investigations of gait and stance are largely missing during the acute stage o...
Changes in corticosteroid and non-steroidal immunosuppressive therapy with long-term zilucoplan treatment in generalized myasthenia gravis [0.03%]
长期使用zilucoplan治疗全身性重症肌无力时糖皮质激素和非甾体类免疫抑制剂的调整变化研究
Channa Hewamadduma,Miriam Freimer,Angela Genge et al.
Channa Hewamadduma et al.
Background: The efficacy and safety of complement component 5 inhibitor zilucoplan in patients with anti-acetylcholine receptor antibody-positive generalized myasthenia gravis (gMG) were assessed in two double-blind studi...
Randomized Controlled Trial
Journal of neurology. 2025 Jun 12;272(7):457. DOI:10.1007/s00415-025-13113-0 2025
Patent foramen ovale diagnosis in young stroke patients: analysis of recurrence and mortality [0.03%]
年轻卒中患者卵圆孔未闭的诊断：复发和死亡率分析
Eva Giralt-Steinhauer,Elisa Cuadrado-Godia,Ana Rodriguez-Campello et al.
Eva Giralt-Steinhauer et al.
Background: Revised European Stroke Organization guidelines in 2018 recommend early patent foramen ovale (PFO) detection and closure in patients aged 60 or younger who suffered an ischemic stroke. Our primary aim was to a...
Burden of pathogenetic and likely pathogenetic variants in SPG7, SPG11 and AP4 genes in Amyotrophic Lateral Sclerosis. A case-control study [0.03%]
SPG7、SPG11和AP4基因的致病和可能致病突变在肌萎缩侧索硬化症中的负担。一项病例对照研究
Paolo Niccolò Doronzio,Serena Lattante,Daniela Bernardo et al.
Paolo Niccolò Doronzio et al.
Background: There is evidence that some Hereditary Spastic Paraplegia (HSP) genes are linked to Amyotrophic Lateral Sclerosis (ALS). In particular, KIF5A and SPG11 genes, which cause two different forms of HSP, are also a...
Retinal neuronal loss and progression independent of relapse activity in multiple sclerosis [0.03%]
多发性硬化症中与复发无关的视网膜神经元丢失和病情进展
Federico Burguet Villena,Nuria Cerdá-Fuertes,Lisa Hofer et al.
Federico Burguet Villena et al.
Background: In multiple sclerosis (MS), inner retinal thinning measured by optical coherence tomography (OCT) is related to lesional and gray matter changes of the brain. ...
The impact of autoimmune comorbidities on the onset attack recovery in adults with AQP4-NMOSD and MOGAD [0.03%]
自身免疫合并症对成人AQP4-NMOSD和MOGAD患者发作、病程及恢复的影响
Sara Samadzadeh,Fiona Chan,Anna Francis et al.
Sara Samadzadeh et al.
Background: Aquaporin-4 neuromyelitis optica spectrum disorder (AQP4-NMOSD) often coexists with other autoimmune diseases (AIDs), whereas such comorbidities are less common in myelin oligodendrocyte glycoprotein antibody ...
Osteopontin levels in the serum reflect anatomical disease progression in patients with amyotrophic lateral sclerosis [0.03%]
肌萎缩侧索硬化患者血清骨桥素水平反映其解剖位置的疾病进展状况
Tommaso Russo,Teuta Domi,Paride Schito et al.
Tommaso Russo et al.
Background: Amyotrophic lateral sclerosis (ALS) lacks biomarkers for diagnosis, prognostic stratification, and evaluation of response to potential treatments. Previous research supported the role of serum osteopontin (OPN...