Comparing the efficacy and safety of cyclophosphamide, infliximab and methotrexate in neurosarcoidosis: a multicenter retrospective study [0.03%]
环磷酰胺、英夫利昔单抗和甲氨蝶呤治疗神经系统结节病的疗效及安全性的多中心回顾性研究
Hélène Gomez,Nicolas Noël,Jean Schmidt et al.
Hélène Gomez et al.
Introduction: Neurosarcoidosis is a granulomatous disease affecting 10% of patients with sarcoidosis. In lack of standardized guidelines, various therapeutic strategies exist. Beyond corticosteroids, cyclophosphamide, inf...
Comparative Study
Journal of neurology. 2025 Jul 24;272(8):531. DOI:10.1007/s00415-025-13242-6 2025
Reliability of serum neurofilament light and glial fibrillary acidic protein for detecting disease activity upon discontinuation of first-line disease-modifying therapy in stable multiple sclerosis (DOT-MS) [0.03%]
一线疾病修正治疗停药的稳定型多发性硬化症患者血清神经丝轻链和胶质纤维酸性蛋白检测疾病活动性的可靠性(DOT-MS)研究
W H Fung,M H J Wessels,E M E Coerver et al.
W H Fung et al.
Background: Neurofilament light(NfL) and glial fibrillary acidic protein(GFAP) are associated with disease activity in multiple sclerosis(MS), however use in monitoring remains limited. The ability of these biomarkers to ...
Randomized Controlled Trial
Journal of neurology. 2025 Jul 23;272(8):530. DOI:10.1007/s00415-025-13231-9 2025
Management and burden of disease in people with myelin oligodendrocyte glycoprotein antibody-associated disease: data from an international, cross-sectional survey [0.03%]
髓少突胶质细胞糖蛋白抗体相关疾病的管理及疾病负担：来自国际横断面调查的数据
F Paul,S Zappacosta,S Narduzzi et al.
F Paul et al.
Background: There are challenges in the diagnosis of myelin-oligodendrocyte glycoprotein (MOG) antibody-associated disease (MOGAD), and a current lack of targeted treatments. This study investigated the disease management...
MOG-IgG detection in serum and cerebrospinal fluid: diagnostic implications and clinical correlates in adult-onset Chinese MOGAD patients [0.03%]
血清和脑脊液中MOG-IgG检测的诊断意义及成人发病中国MOGAD患者的临床特征分析
Yuwei Dai,Qing Yin,Binhong Han et al.
Yuwei Dai et al.
Objective: To assess the diagnostic significance and clinical features of cerebrospinal fluid (CSF)-restricted MOG-IgG in Chinese adults with MOG-IgG-associated disease (MOGAD), and to compare phenotypes across MOG-IgG st...
The predictive value of social cognition assessment for 1-year follow-up functional outcomes in behavioral variant frontotemporal dementia [0.03%]
行为变体额颞叶痴呆患者社会认知评估对1年随访功能结局的预测价值
Electra Chatzidimitriou,Yu Chen,Despina Moraitou et al.
Electra Chatzidimitriou et al.
Background and objectives: Behavioral variant frontotemporal dementia (bvFTD) is characterized by prominent socioemotional deficits that negatively impact daily living. This study aims to identify the strongest socioemoti...
Object but no room tilt illusion due to apperceptive visual agnosia in a right parieto-occipital lesion disconnecting visual-spatial integration [0.03%]
由于右顶枕区病变破坏视觉空间整合而导致的无房间倾斜错觉的物体知觉障碍性失认症
Philipp J Koch,Tabea Kürten,Anja Fellbrich et al.
Philipp J Koch et al.
Exploring the phenotypic fingerprints of ANXA11 variants in ALS: a population-based study in an European cohort [0.03%]
ANXA11基因变异在ALS中的表型特征的欧洲人群基于队列研究
Francesca Palumbo,Barbara Iazzolino,Cristina Moglia et al.
Francesca Palumbo et al.
Background: Annexin A11 (ANXA11) has emerged as a significant gene associated with amyotrophic lateral sclerosis (ALS) and cognitive impairments. This study aimed to evaluate the prevalence and clinical and cognitive feat...
Asleep versus awake deep brain stimulation in the treatment of Parkinson disease: a systematic review and meta-analysis [0.03%]
清醒与麻醉下深部脑刺激治疗帕金森病的系统评价和 meta 分析
Xin Wang,Lu Tian
Xin Wang
Objective: There remains controversies regarding the selection of anesthesia method in the procedure of deep brain stimulation (DBS) for Parkinson disease (PD). This study was to compare the efficacy and safety between as...
In search of the optimal MRI marker for progressive supranuclear palsy: a large, single-center, retrospective study on the effect of phenotype, diagnostic certainty and disease duration [0.03%]
寻找进行性核上性麻痹最佳MRI标志物：一项关于表型、诊断确定性和疾病持续时间影响的大样本单中心回顾性研究
Vasilios C Constantinides,Nikolaos Giagkou,Maria-Evgenia Brinia et al.
Vasilios C Constantinides et al.
Introduction: Multiple MRI markers have been introduced as surrogate markers of progressive supranuclear palsy (PSP). Midbrain surface, midbrain/pons surface ratio (M/P) and the Magnetic Resonance Parkinsonism Index (MRPI...
Serum GFAP and NFL as biomarkers for disease activity, severity and disability in NMOSD [0.03%]
NMOSD中血清GFAP和NFL作为疾病活动度、严重程度和残疾生物标志物的价值评估
Rui Wang,Xiaofei Wang,Dongren Sun et al.
Rui Wang et al.
Objective: Serum glial fibrillary acidic protein (sGFAP) and neurofilament light chain (sNfL) levels are potential biomarkers for disease activity and disability in Neuromyelitis Optica Spectrum Disorder (NMOSD), respecti...