Diagnostic utility of tectal plate measures in clinical variants of progressive supranuclear palsy [0.03%]
临床进行性核上性麻痹变异型的诊断标志-tectal plate测量指标的价值研究
Neha Singh-Reilly,Morgan Blakey,Ryota Satoh et al.
Neha Singh-Reilly et al.
Background: The length of the tectal plate, which sits above the midbrain, is reduced in both the Richardson's syndrome (RS) and parkinsonism (P) variants of progressive supranuclear palsy (PSP). However, it is unclear wh...
Saccadic eye movements in neurological disease: cognitive mechanisms and clinical applications [0.03%]
神经疾病中的扫视眼动：认知机制及临床应用
Yong Lin Wang,Mahima Kapoor,Joanne Fielding et al.
Yong Lin Wang et al.
Saccadic eye movements are rapid, precisely coordinated shifts that centre the fovea on a visual target. Their control relies on the integration of cognitive processes spanning multiple brain regions. High-resolution video-oculography enabl...
Stroke thrombolysis for patients with intracranial aneurysms: a nationwide cohort study [0.03%]
颅内动脉瘤患者溶栓治疗：基于全国队列的研究
Huanwen Chen,Matthew K McIntyre,Ajay Malhotra et al.
Huanwen Chen et al.
Background: The safety of intravenous thrombolysis (IVT) in acute ischemic stroke (AIS) patients with underlying unruptured intracranial aneurysms (UIAs) is unclear. This study evaluates IVT safety and efficacy in AIS pat...
Lung function and the risk of Parkinson's disease: a population-based cohort study [0.03%]
基于人群的队列研究中肺功能和帕金森病发病风险的关系
Jiyong Liu,Shichan Wang,Xiaoting Zheng et al.
Jiyong Liu et al.
Objective: Some researchers have noted a faster decline in lung function among Parkinson's disease (PD) patients compared to healthy individuals. However, the relationship between lung function and the risk of developing ...
Comprehensive observations and multidisciplinary approaches (COMA) in the management of unconscious patients: a prospective high fidelity simulation study [0.03%]
综合观察和多学科方法（COMA）在意识障碍患者管理中的应用：前瞻性高保真模拟研究
Nüesch Liliane,Kai Tisljar,Sebastian Berger et al.
Nüesch Liliane et al.
Background: Managing patients with coma of unknown etiology presents a challenge requiring rapid, structured assessment. We aimed to examine how physicians from different specialties manage patients with coma of unknown e...
Observational Study
Journal of neurology. 2025 Jul 25;272(8):537. DOI:10.1007/s00415-025-13228-4 2025
Neurofilament light chain reference values in serum and cerebrospinal fluid: a bi-compartmental analysis in neurological diseases [0.03%]
神经疾病中神经丝轻链的参考值：血清和脑脊液中的双隔室分析
Steffen Halbgebauer,Veronika Klose,Badrieh Fazeli et al.
Steffen Halbgebauer et al.
Background: Concentrations of neurofilament light chain (NfL), a neuroaxonal damage marker, increase with age. Therefore, age-dependent reference values are important in clinical practice. However, so far these have only ...
Learning as a digital hallmark of cognition in multiple sclerosis: lessons from a digital symbol digit modalities test [0.03%]
作为认知障碍数字标志的学习：来自数字化符号数字模式测试的启示
Michelangelo Dini,Marta Tacchini,Giulia Gamberini et al.
Michelangelo Dini et al.
Background: Multiple Sclerosis (MS) often causes cognitive impairment that significantly impacts functional independence. The Symbol Digit Modalities Test (SDMT) is the gold standard for screening and monitoring cognitive...
Interaction of metabolic and inflammatory dysregulation on central degeneration and cognitive function in behavioral variant Frontotemporal dementia [0.03%]
代谢和炎症紊乱在行为变异型额颞叶痴呆中对中枢神经退行性和认知功能的交互作用
Jia-Hui Hou,Min Chu,Zhong-Yun Chen et al.
Jia-Hui Hou et al.
Background: Metabolic and inflammation dysregulation are important mechanisms in neurodegenerative diseases, but their study in behavioral variant frontotemporal dementia (bvFTD) is very scarce; we aimed to investigate th...
Variation in the reported prevalence of Huntington's disease: a systematic review and guide to interpretation [0.03%]
亨廷顿舞蹈病流行率的报告差异：系统评价及解读指南
Alexander Thompson,Oliver Quarrell,Mark Strong
Alexander Thompson
There is significant variation in the reported estimates of Huntington's disease (HD) prevalence in different settings. This systematic review was undertaken to describe and assess the sources of heterogeneity in estimated prevalence values...
Serum GFAP predicts survival in advanced ALS: a prospective multicenter study [0.03%]
前瞻性多中心研究血清GFAP预测晚期ALS患者的生存期
Hee-Jae Jung,Woo-Seung Jeong,Heung-Won Kang et al.
Hee-Jae Jung et al.
Background: Neurofilament light chain (NfL) is a well-established biomarker of axonal damage in amyotrophic lateral sclerosis (ALS), but its limited disease specificity warrants the identification of complementary markers...
Multicenter Study
Journal of neurology. 2025 Jul 24;272(8):532. DOI:10.1007/s00415-025-13272-0 2025