Predictive clinical factors for the progression from idiopathic late-onset cerebellar ataxia to multiple system atrophy cerebellar type [0.03%]
特发性晚发小脑共济失调向多系统萎缩小脑型进展的预测临床因素
Seungmin Lee,Seoyeon Kim,Bora Jin et al.
Seungmin Lee et al.
Objectives: Patients initially diagnosed with idiopathic late-onset cerebellar ataxia (ILOCA) may develop multiple system atrophy cerebellar type (MSA-C). However, data on conversion time, associated clinical factors, and...
Characteristics of MRI lesions in AQP4 antibody-positive NMOSD, MOGAD, and multiple sclerosis: a systematic review and meta-analysis [0.03%]
AQP4抗体阳性NMOSD、MOGAD和多发硬化症的MRI病变特征：系统评价和Meta分析
Unnah Leitner,Sin Hong Chew,Jessica Blanch et al.
Unnah Leitner et al.
Background and objectives: Multiple sclerosis (MS), aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-Ab + ve NMOSD), and myelin oligodendrocyte glycoprotein-associated disease (MOGAD) are demyeli...
Meta-Analysis
Journal of neurology. 2025 Aug 7;272(9):560. DOI:10.1007/s00415-025-13303-w 2025
Real-world comparison of lymphopenia profiles in S1P receptor modulators for multiple sclerosis: a multicenter retrospective study [0.03%]
一种和MSRR中淋巴细胞减少谱系的现实世界对比研究：多中心回顾性研究
Giorgia Teresa Maniscalco,Maddalena Sparaco,Maria Di Gregorio et al.
Giorgia Teresa Maniscalco et al.
Introduction: Sphingosine-1-phosphate (S1P) receptor modulators, regulating the S1P/S1PR pathway, lead to lymphocyte sequestration in lymphoid organs, which results in peripheral lymphopenia. This study evaluates the degr...
Comparative Study
Journal of neurology. 2025 Aug 6;272(9):559. DOI:10.1007/s00415-025-13300-z 2025
Diagnostic challenges in vestibular migraine-clinical differentiation from Menière's disease and discrepancies with current classification criteria [0.03%]
前庭性偏头痛的诊断难题——与梅尼埃病的临床鉴别及对现行分类标准的质疑
Doreen Huppert,Eva Grill,Sandra Becker-Bense et al.
Doreen Huppert et al.
Background: Vestibular migraine (VM) and Menière's disease (MD) are spontaneous episodic vestibular syndromes and often present with overlapping features, making clinical differentiation challenging. This study aimed to ...
Spinal cord structural changes in SPG4: insights from a large cohort using advanced neuroimaging [0.03%]
SPG4型脊髓空洞症患者的脊髓结构改变：来自大样本的高级神经影像学见解
Carelis González-Salazar,Luciana R Pimentel-Silva,Thiago J R Rezende et al.
Carelis González-Salazar et al.
Background: SPG4 is the most common autosomal dominant hereditary spastic paraplegia (HSP), a neurodegenerative disorder characterized by progressive spasticity and weakness in the lower limbs due to corticospinal tract a...
Altered static and dynamic spontaneous brain activity patterns in spinocerebellar ataxia type3 patients [0.03%]
脊髓小脑性共济失调3型患者静息态大脑功能和功能连接的改变
Runhua Sha,Chao Wu,Haishan Qiu et al.
Runhua Sha et al.
Background: Spinocerebellar ataxia type 3 (SCA3) is characterized by extensive supra- and infra-tentorial brain injuries, beginning in the pre-symptomatic stage. However, the alterations and evolution of spontaneous brain...
Clinical efficacy of GLP-1 receptor agonists in the treatment of Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials [0.03%]
胰高血糖素样肽-1受体激动剂治疗帕金森病的临床疗效：随机对照试验的系统评价和.meta.分析
Yujing Zhang,Cong Wang,Yuqing Wang et al.
Yujing Zhang et al.
Background: Parkinson's disease (PD) is a degenerative disorder of the nervous system. The neurobiological implications of glucagon-like peptide-1 receptor agonists (GLP-1RAs) in modifying PD risk profile remain incomplet...
Hyesoo Kwon,Hyun Ah Kim
Hyesoo Kwon
Advanced multiple sclerosis: an exploratory study on a neglected patient population [0.03%]
对一个被忽视的患者群体进行的探索性研究——晚期多发性硬化症患者探究
Omar Keritam,Oliver Ascoli,Andrea Harsanyi et al.
Omar Keritam et al.
Background: Multiple sclerosis (MS) is a chronic immune-mediated disease that can cause severe physical and cognitive disability. While modern therapies have improved outcomes in relapsing MS, patients with advanced disea...
Distributions and network changes of brain activity in the acute phase of anti-NMDAR encephalitis: a MEG study [0.03%]
抗NMDAR脑炎急性期脑活动分布及网络变化的MEG研究
Qiqi Chen,Yun Ma,Zonghong Li et al.
Qiqi Chen et al.
Objective: This study aimed to elucidate the distributions of abnormal activities, as well as the functional connectivity and topological properties of brain networks, in patients diagnosed with anti-N-methyl-D-aspartate ...