Association between weekend recovery sleep and risk of incident dementia: a prospective cohort study in the UK Biobank [0.03%]
英国生物银行中周末补觉与痴呆症发病风险之间关系的前瞻性队列研究
Bo Zhao,Shaojiong Zhou,Jie Chang et al.
Bo Zhao et al.
Background: Sleep deprivation has been linked to higher dementia risk, but the role of weekend recovery sleep (WRS) in mitigating this risk remains unclear. This study aims to evaluate the association between WRS and deme...
Giulia Sofia Cereda,Antonio Farina,Nolwenn Billet et al.
Giulia Sofia Cereda et al.
Age-related differences in switching highly effective disease-modifying therapy in patients with multiple sclerosis [0.03%]
多发性硬化症患者的高效疾病修正治疗转换与年龄相关的差异
David Ellenberger,Niklas Frahm,Alexander Stahmann et al.
David Ellenberger et al.
Background: High efficacy therapies (HET) play a crucial role in multiple sclerosis (MS) management. HET discontinuation/de-escalation is a critical decision, especially in different age groups, due to potential changes i...
A new screening tool for early recognition of ATTRv polyneuropathy in clinical practice: AmyloScan® [0.03%]
一种新的临床筛查工具：AmyloScan®，用于ATTRv多发性神经病变的早期识别
Juliane Sachau,Lena Rhode,Maike F Dohrn et al.
Juliane Sachau et al.
Hereditary transthyretin (ATTRv) amyloidosis is a progressive multisystem disorder, mainly characterized by cardiac dysfunction and polyneuropathy. Due to its rarity and heterogeneous presentation, diagnosis is often delayed, which has a di...
The impact of autoimmune comorbidities on multiple sclerosis progression: insights from a longitudinal single-center study [0.03%]
自身免疫合并症对多发性硬化病进展的影响：来自纵向单中心研究的新见解
Derya Aslan,Sabrina Bourabia,Bernd Kowall et al.
Derya Aslan et al.
Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system. The presence of other conditions alongside MS imposes a substantial personal and socioeconomic burden. In particular, the impact of comorbid au...
Progressive retinal and microvascular neurodegeneration in neuromyelitis optica spectrum disorders: a longitudinal SS-OCT/OCTA study [0.03%]
NMOSD视神经和视网膜微血管纵向SS-OCT/OCTA退行性改变研究
Lingyao Kong,Xiaofeng Tan,Hang Wang et al.
Lingyao Kong et al.
Background: Emerging evidence suggests that subclinical visual pathway impairment might occur in neuromyelitis optica spectrum disorder (NMOSD) independently of optic neuritis (ON). This prospective longitudinal cohort st...
Olfactory function is longitudinally associated with semantic fluency in Parkinson's disease: a cohort study [0.03%]
纵向队列研究嗅觉功能与帕金森病语义流畅度的关系
Dareia S Roos,Henk W Berendse,Richard L Doty et al.
Dareia S Roos et al.
Background: Olfactory dysfunction is an early, common, and progressive symptom in Parkinson's disease (PD). Whether the decline in olfactory function is longitudinally associated with a deterioration of (non-)motor sympto...
Advancing personalized spinal muscular atrophy care: matching the right biomarker to the right patient at the right time [0.03%]
推进脊髓性肌萎缩症的个性化治疗：在正确的时间为合适的患者匹配正确的生物标志物
Stefania Corti,Linda Ottoboni,Valeria Sansone
Stefania Corti
With the advent of survival motor neuron (SMN)-enhancing therapies, the natural course of spinal muscular atrophy (SMA) has been reshaped, unveiling new patient phenotypes. As therapeutic options expand, there is an increasing demand for ro...
Guidelines adherence in status epilepticus first steps treatment: factors associated with non-compliance and effect on outcome [0.03%]
癫痫持续状态初始治疗依从性指南的影响因素及其对预后的影响研究
Valérie Geiser-Micheloud,Andrea O Rossetti,Vincent Alvarez
Valérie Geiser-Micheloud
Objective: We investigate adherence to acute-phase treatment guidelines for status epilepticus (SE) in a university and a community hospital, assessing factors influencing compliance and its impact on SE duration and outc...
Dynamic visual acuity in bilateral vestibulopathy and healthy age-sex-matched participants [0.03%]
双侧前庭病变患者的动态视力与健康匹配对照组的比较研究
Meichan Zhu,Lisa van Stiphout,Benjamin Volpe et al.
Meichan Zhu et al.
Objectives: Dynamic visual acuity (DVA) can be assessed on a treadmill while walking at different speeds and is used to assess people with bilateral vestibulopathy (BVP). However, the effects and interactions of age, BVP,...